CMB and SZ effect separation with Constrained Internal Linear Combinations

The `Internal Linear Combination' (ILC) component separation method has been extensively used on the data of the WMAP space mission, to extract a single component, the CMB, from the WMAP multifrequency data. We extend the ILC approach for reconstructing millimeter astrophysical emissions beyond the CMB alone. In particular, we construct a Constrained ILC to extract clean maps of both the CMB or the thermal Sunyaev Zeldovich (SZ) effect, with vanishing contamination from the other. The performance of the Constrained ILC is tested on simulations of Planck mission observations, for which we successfully reconstruct independent estimates of the CMB and of the thermal SZ.Comment: 7 pages, 3 figures, submitted to MNRA

Foreground component separation with generalised ILC

The 'Internal Linear Combination' (ILC) component separation method has been extensively used to extract a single component, the CMB, from the WMAP multifrequency data. We generalise the ILC approach for separating other millimetre astrophysical emissions. We construct in particular a multidimensional ILC filter, which can be used, for instance, to estimate the diffuse emission of a complex component originating from multiple correlated emissions, such as the total emission of the Galactic interstellar medium. The performance of such generalised ILC methods, implemented on a needlet frame, is tested on simulations of Planck mission observations, for which we successfully reconstruct a low noise estimate of emission from astrophysical foregrounds with vanishing CMB and SZ contamination.Comment: 11 pages, 6 figures (2 figures added), 1 reference added, introduction expanded, V2: version accepted by MNRA

The International Linear Collider

In this article, we describe the key features of the recently completed technical design for the International Linear Collider (ILC), a 200-500 GeV linear electron-positron collider (expandable to 1 TeV) that is based on 1.3 GHz superconducting radio-frequency (SCRF) technology. The machine parameters and detector characteristics have been chosen to complement the Large Hadron Collider physics, including the discovery of the Higgs boson, and to further exploit this new particle physics energy frontier with a precision instrument. The linear collider design is the result of nearly twenty years of R&D, resulting in a mature conceptual design for the ILC project that reflects an international consensus. We summarize the physics goals and capability of the ILC, the enabling R&D and resulting accelerator design, as well as the concepts for two complementary detectors. The ILC is technically ready to be proposed and built as a next generation lepton collider, perhaps to be built in stages beginning as a Higgs factory.Comment: 41 page

Learning for Advanced Motion Control

Iterative Learning Control (ILC) can achieve perfect tracking performance for mechatronic systems. The aim of this paper is to present an ILC design tutorial for industrial mechatronic systems. First, a preliminary analysis reveals the potential performance improvement of ILC prior to its actual implementation. Second, a frequency domain approach is presented, where fast learning is achieved through noncausal model inversion, and safe and robust learning is achieved by employing a contraction mapping theorem in conjunction with nonparametric frequency response functions. The approach is demonstrated on a desktop printer. Finally, a detailed analysis of industrial motion systems leads to several shortcomings that obstruct the widespread implementation of ILC algorithms. An overview of recently developed algorithms, including extensions using machine learning algorithms, is outlined that are aimed to facilitate broad industrial deployment.Comment: 8 pages, 15 figures, IEEE 16th International Workshop on Advanced Motion Control, 202

ILC Cosmology

Recent breakthroughs in cosmology pose questions that require particle physics answers. I review the problems of dark matter, baryogenesis, and dark energy and discuss how particle colliders, particularly the International Linear Collider, may advance our understanding of the contents and evolution of the Universe.Comment: 18 pages, Plenary Colloquium presented at the 2005 International Linear Collider Workshop, Stanford, California, USA, 18-22 March 200

Success rates of re-excision after positive margins for invasive lobular carcinoma of the breast.

Rates of positive margins after surgical resection of invasive lobular carcinoma (ILC) are high (ranging from 18 to 60%), yet the efficacy of re-excision lumpReceptor subtypeectomy for clearing positive margins is unknown. Concerns about the diffuse nature of ILC may drive increased rates of completion mastectomy to treat positive margins, thus lowering breast conservation rates. We therefore determined the success rate of re-excision lumpectomy in women with ILC and positive margins after surgical resection. We identified 314 cases of stage I-III ILC treated with breast conserving surgery (BCS) at the University of California, San Francisco. Surgical procedures, pathology reports, and outcomes were analyzed using univariate and multivariate statistics and Cox-proportional hazards models. We evaluated outcomes before and after the year 2014, when new margin management consensus guidelines were published. Positive initial margins occurred in 118 (37.6%) cases. Of these, 62 (52.5%) underwent re-excision lumpectomy, which cleared the margin in 74.2%. On multivariate analysis, node negativity was significantly associated with successful re-excision (odds ratio [OR] 3.99, 95% CI 1.15-13.81, p = 0.029). After 2014, we saw fewer initial positive margins (42.7% versus 25.5%, p = 0.009), second surgeries (54.6% versus 20.2%, p < 0.001), and completion mastectomies (27.7% versus 4.5%, p < 0.001). In this large cohort of women with ILC, re-excision lumpectomy was highly successful at clearing positive margins. Additionally, positive margins and completion mastectomy rates significantly decreased over time. These findings highlight improvements in management of ILC, and suggest that completion mastectomy may not be required for those with positive margins after initial BCS