3 research outputs found
Rhodium-Catalyzed Dehydrogenative Coupling of Phenylheteroarenes with Alkynes or Alkenes
Benzo-fused
tri- to heptacyclic heteroarenes were effectively constructed
by the rhodium-catalyzed dehydrogenative coupling of phenylheteroarenes
with alkynes. Using alkenes as coupling partners, dehydrogenative
alkenylation took place selectively on the phenyl moiety of phenylheteroarenes.
Several experiments with deuterium-labeled substrates indicated that
double C–H bond cleavages take place even in the reaction with
alkenes
Rhodium-Catalyzed C3-Selective Alkenylation of Substituted Thiophene-2-carboxylic Acids and Related Compounds
The
regioselective C3-alkenylation of thiophene-2-carboxylic acids
can be achieved effectively via rhodium/silver-catalyzed oxidative
coupling with alkenes, unaccompanied by decarboxylation. A wide range
of substrates including brominated thiophenecarboxylic acids and furan-2-carboxylic
acids can be employed together with styrenes as well as acrylates.
The present catalyst system is also applicable to ortho-alkenylation
of benzoic acids