573 research outputs found
Clusters of Super Massive Black Holes in the Central Region of Our Galaxy Observed by Decameter Radio Wave Pulses: - Discovery of 24 Super Massive Black Holes and Their Motions
Discovery of a Pulsating Component in a Decametric Frequency Range Suggesting a Rotating Super Black Hole at the Galactic Center as a Source
Influence of Pb and La Contents on the Lattice Configuration of La-Substituted Pb(Zr,Ti)O3 Films Fabricated by CSD method
Further evidence for a male-selective genetic association of synapse-associated protein 97 (SAP97) gene with schizophrenia
Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle
The concept of the plasticity or transdifferentiation of adult stem cells has been challenged by the phenomenon of cell fusion. In this work, we examined whether neonatal cardiomyocytes fuse with various somatic cells including endothelial cells, cardiac fibroblasts, bone marrow cells, and endothelial progenitor cells spontaneously in vitro. When cardiomyocytes were cocultured with endothelial cells or cardiac fibroblasts, they fused and showed phenotypes of cardiomyocytes. Furthermore, cardiomyocytes reentered the G2-M phase in the cell cycle after fusing with proliferative noncardiomyocytes. Transplanted endothelial cells or skeletal muscle–derived cells fused with adult cardiomyocytes in vivo. In the cryoinjured heart, there were Ki67-positive cells that expressed both cardiac and endothelial lineage marker proteins. These results suggest that cardiomyocytes fuse with other cells and enter the cell cycle by maintaining their phenotypes
Enhancement of ferroelectric and magnetic properties in BiFeO3 films by small amount of cobalt addition
- …