27 research outputs found

    The Relationship of Cyclooxygenase -2 (COX-2) Expression with Clinical Presentation, Staging, and Degree of Differentiation in Colorectal Cancer

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    Colorectal cancer (CRC) is a common malignancy worldwide. Although the recent development of adjuvant treatment has developed rapidly, it has only slightly Increased the survival rate of CRC Patients in an advanced stage. The prognosis of CRC patient strongly influenced by Several factors, such as tumor stage, clinical manifestations, histopathology and molecular oncogenicity of the tumor. COX-2 is an enzyme that plays a role in converting arachidonic acid into prostaglandins. The end product of COX-2 contributes to various biological factors in triggering tumor growth. The purpose of this research is to know the relationship of COX-2 expression with the clinical presentation such as patient age, location, and size of the tumor and histopathology in CRC patients

    Multi-Locus Variable-Number Tandem Repeat Profiling of Salmonella enterica Serovar Typhi Isolates from Blood Cultures and Gallbladder Specimens from Makassar, South-Sulawesi, Indonesia

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    Multi-locus variable-number tandem repeat analysis differentiated 297 Salmonella enterica serovar Typhi blood culture isolates from Makassar in 76 genotypes and a single unique S. Typhi genotype was isolated from the cholecystectomy specimens of four patients with cholelithiasis. The high diversity in S. Typhi genotypes circulating in Makassar indicates that the number of carriers could be very large, which may complicate disease prevention and control
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