Cross sectional evaluation of the gut-microbiome metabolome axis in an Italian cohort of IBD patients.

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract of uncertain origin, which includes ulcerative colitis (UC) and Crohn's disease (CD). The composition of gut microbiota may change in IBD affected individuals, but whether dysbiosis is the cause or the consequence of inflammatory processes in the intestinal tissue is still unclear. Here, the composition of the microbiota and the metabolites in stool of 183 subjects (82 UC, 50 CD, and 51 healthy controls) were determined. The metabolites content and the microbiological profiles were significantly different between IBD and healthy subjects. In the IBD group, Firmicutes, Proteobacteria, Verrucomicrobia, and Fusobacteria were significantly increased, whereas Bacteroidetes and Cyanobacteria were decreased. At genus level Escherichia, Faecalibacterium, Streptococcus, Sutterella and Veillonella were increased, whereas Bacteroides, Flavobacterium, and Oscillospira decreased. Various metabolites including biogenic amines, amino acids, lipids, were significantly increased in IBD, while others, such as two B group vitamins, were decreased in IBD compared to healthy subjects. This study underlines the potential role of an inter-omics approach in understanding the metabolic pathways involved in IBD. The combined evaluation of metabolites and fecal microbiome can be useful to discriminate between healthy subjects and patients with IBD

Fifth European Dirofilaria and Angiostrongylus Days (FiEDAD) 2016

Peer reviewe

Delle societ\ue0 di interesse nazionale

Si individuano le societ\ue0 ad interesse nazionale e la relativa disciplin

Il fallimento dell'impresa pubblica in forma societaria

Si analizzano le problematiche relative alla dichiarazione di fallimento delle imprese pubbliche in forma societaria e le modalit\ue0 attraverso le quali gestire il falliment

Comparative analysis of torsional and bending stresses in two mathematical models of nichel-titanium rotary instruments: ProTaper versus ProFile

During root canal instrumentation, nickel-titanium rotary instruments are subjected to continual stresses inside the canal due to its anatomy and the hardness of the dentin they must cut. They must therefore be both stress-resistant and elastic. This study aimed to compare the mechanical behavior of two nickel-titanium rotary instruments (ProTaper and ProFile) by applying the finite element analysis method to produce a numerical evaluation. The nonlinear mechanical behavior of the alloy was taken into account during the study. The distribution of stresses due to torsional and bending moments was compared in the two experimental models. The ProFile model was found to be more elastic than the ProTaper model. Under equal loads, the ProTaper model showed lower and better distributed stresses than the ProFile model. Copyright © 2002 by The American Association of Endodontists

Societ\ue0 con partecipazione dello Stato o di enti pubblici

Si analizza la disciplina delle nomine dirette delle cariche sociale da parte dello Stato o di altri enti pubblici soc

La crisi d'impresa

Si analizza la crisi d'impresa delle società pubbliche a seguito delle novità introdotte dal testo unico sulle società a partecipazione pubblica (dlgs 175/2016

Skin Lesions in Feline Leishmaniosis: A Systematic Review

Feline leishmaniosis (FeL) is increasingly reported throughout the world and skin lesions predominate in the clinical picture. There are, however, few evidence-based data on cutaneous feline leishmaniosis and directions are strongly needed for a better management of the disease. In this study, we systematically reviewed what is currently known about the clinical dermatological presentation of FeL through analysis of the literature and, further, by adding unpublished cases managed by Italian veterinary dermatologists. Sixty-six feline cases of cutaneous leishmaniosis published in 33 articles between 1990 and 2020 met the inclusion criteria and were analyzed. Six unpublished cases of cutaneous FeL managed by Italian dermatologists were also reviewed. The majority of cases were reported from South America, followed by Europe and North America. Nodules were the most frequently reported clinical signs and the presence of Leishmania in lesioned skin was assessed mainly by cytology. A total of six Leishmania species have been identified as being responsible for skin lesions. Coinfections by FIV or FeLV were reported in 12.1% and 9.1% of the cases, respectively. Clinical data including treatment have been analyzed and discussed to provide directives for proper management of the disease for which cats may also serve as domestic reservoirs for human infections