Quantum theory of damped harmonic oscillator

The exact solutions of the Schrödinger equation for damped harmonic oscillator with pulsating mass and modified Caldirola-Kanai Hamiltonian are evaluated. We also investigated the case of under-damped for the twomodels constructed and the results obtained in both cases do not violate Heisenberg uncertainty principle

Patient Retention and Adherence to Antiretrovirals in a Large Antiretroviral Therapy Program in Nigeria: A Longitudinal Analysis for Risk Factors

Substantial resources and patient commitment are required to successfully scale-up antiretroviral therapy (ART) and provide appropriate HIV management in resource-limited settings. We used pharmacy refill records to evaluate risk factors for loss to follow-up (LTFU) and non-adherence to ART in a large treatment cohort in Nigeria.We reviewed clinic records of adult patients initiating ART between March 2005 and July 2006 at five health facilities. Patients were classified as LTFU if they did not return >60 days from their expected visit. Pharmacy refill rates were calculated and used to assess non-adherence. We identified risk factors associated with LTFU and non-adherence using Cox and Generalized Estimating Equation (GEE) regressions, respectively. Of 5,760 patients initiating ART, 26% were LTFU. Female gender (p < 0.001), post-secondary education (p = 0.03), and initiating treatment with zidovudine-containing (p = 0.004) or tenofovir-containing (p = 0.05) regimens were associated with decreased risk of LTFU, while patients with only primary education (p = 0.02) and those with baseline CD4 counts (cell/ml(3)) >350 and <100 were at a higher risk of LTFU compared to patients with baseline CD4 counts of 100-200. The adjusted GEE analysis showed that patients aged <35 years (p = 0.005), who traveled for >2 hours to the clinic (p = 0.03), had total ART duration of >6 months (p<0.001), and CD4 counts >200 at ART initiation were at a higher risk of non-adherence. Patients who disclosed their HIV status to spouse/family (p = 0.01) and were treated with tenofovir-containing regimens (p < or = 0.001) were more likely to be adherent.These findings formed the basis for implementing multiple pre-treatment visit preparation that promote disclosure and active community outreaching to support retention and adherence. Expansion of treatment access points of care to communities to diminish travel time may have a positive impact on adherence

Bacterial meningitis in adults at the University of Calabar Teaching Hospital. A5-year retrospective study 1993-97

A retrospective study of cases of adult Bacterial meningitis managed at the University of Calabar Teaching Hospital Calabar over a 5 –Year period (1993-97) was carried out to determine the Clinical presentation, morbidity and the management outcomes during the survey period. A total of 68 patients whose case records were found intact were selected for the study. The case records of these patients were reviewed for clinical features on presentation, the initial results of investigations mainly lumber puncture and cerebrospinal fluid analysis and nature of culprit organism. The management outcome of each patient was also noted. The study reveled that forty one out of 66 patients recovered fully from the illness after treatment, nineteen patients died and six patients left against medical advice. The predicator of morbidity and mortality were (a) late presentation with altered levels of consciousness or outright coma; (b) early presentation while fully conscious and (c) inadequate/ inappropriate medication prior to arrived in hospital. Mortality rate was higher among patients who received inadequate antibiotics, presented late for treatment; and in those presenting with altered level of consciousness. The mortality rate was 59 and 52% respectively. The values for each category were statistically significant when compared with mortality rates of patients who presented very early for treatment, had adequate doses of antibiotics, and were fully conscious on arrival and during treatment,

Paragonimiasis

[Extract] Paragonimiasis is a zoonotic disease caused by lung flukes of the genus Paragonimus. Humans usually become infected by eating freshwater crabs or crayfish containing encysted metacercariae of these worms. However, an alternative route of infection exists: ingestion of raw meat from a mammalian paratenic host. Adult worms normally occur in pairs in cysts in the lungs from which they void their eggs via air passages. The pulmonary form is typical in cases of human infection due to P. westermani, P. heterotremus and a few other species (Table 5.1). Worms may occupy other sites in the body, notably the brain, but lung flukes have made their presence felt in almost every organ. Ectopic paragonimiasis is particularly common when infection is due to members of the P. skrjabini complex (Table 5.1). Human paragonimiasis occurs primarily in the tropics and subtropics of Asia, Africa, and the Americas, with different species being responsible in different areas (Table 5.1)

Paragonimiasis

[Extract] Paragonimiasis is a zoonotic disease caused by lung flukes of the genus Paragonimus. Humans usually become infected by eating freshwater crabs or crayfish containing encysted metacercariae of these worms. However, an alternative route of infection exists: ingestion of raw meat from a mammalian paratenic host. Adult worms normally occur in pairs in cysts in the lungs from which they void their eggs via air passages. The pulmonary form is typical in cases of human infection due to P. westermani, P. heterotremus, and a few other species (Table 5.1). Worms may occupy other sites in the body, notably the brain, but lung flukes have made their presence felt in almost every organ. Ectopic paragonimiasis is particularly common when infection is due to members of the P. skrjabini complex (Table 5.1). Human paragonimiasis occurs primarily in the tropics and subtropics of Asia, Africa, and the Americas, with different species being responsible in different areas (Table 5.1)