Application of Asymmetric Flow Field-Flow Fractionation hyphenations for liposome–antimicrobial peptide interaction

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Professional activity, information demands, training and updating needs of occupational medicine physicians in Italy: National survey.

Objectives: Occupational medicine is a discipline continually evolving in response to technological advances, changes in workplaces and production processes, emergence of new occupational risks and diseases and modifications in regulatory framework for occupational health and safety. Therefore, the recurrent revaluation of professional activity, information demands and education and training needs of occupational physicians is essential in order to identify methodologies and tools that may contribute to improvement of their professional knowledge and competency. In this regard, we conducted the first large-scale national survey of Italian occupational medicine physicians to define their demographic and professional activity and to assess their information demands, training and updating needs. Material and Methods: A random sample of occupational physicians, listed in the national register of the Italian Ministry of Health, was selected to complete a voluntary survey. Subjects recruited in this study were asked to complete 3 different sections (personal and professional information, training and updating needs, professional activity and practice characteristics) of a questionnaire for a total of 35 questions. Results: Most of participants were specialized in occupational medicine, worked for a large number of companies and carried out health surveillance on a total number of workers that exceeds 1500. Occupational physicians would like to have a higher training offer towards practical aspects of health surveillance, risks assessment, manual handling of loads, chemical substances and upper limb biomechanical overload. Interestingly, statistically significant differences were observed subdividing the sample into different groups according to the legal requirements to perform the professional activity of occupational physicians in Italy or according to particular aspects of their professional activity. Conclusions: This study has provided interesting findings that may help to guide future discussion on alternative and additional instruments and/or methodologies that may be adopted to implement the quality and effectiveness of occupational medicine practice. Int J Occup Med Environ Health 2016;29(5):837–85

Quantification of interacting cognate odorants with olfactory receptors in nanovesicles

This study aims to improve our understanding of the interaction between olfactory receptors and odorants to develop highly selective biosensing devices. Natural nanovesicles (NVs) from Saccharomyces cerevisiae, ~100 nm in diameter, carrying either the human OR17-40 or the chimpanzee OR7D4 olfactory receptor (OR) tagged with the c-myc epitope at their N-terminus, are presented as model systems to quantify the interaction between odorant and olfactory receptors. The level of expression of olfactory receptors was determined at individual NVs using a novel competitive ELISA immunoassay comparing the values obtained against those from techniques involving the solubilization of cell membrane proteins and the identification of c-myc-carrying receptors. Surface Plasmon Resonance (SPR) measurements on L1 Biacore chips indicate that cognate odorants bind to their Ors, thereby quantifying the approximate number of odorants that interact with a given olfactory receptor. The selectivity of OR17-40-carrying NVs towards helional and OR7D4-carrying NVs towards androstenone has been proven in cross-check experiments with non-specific odorant molecules (heptanal and pentadecalactone, respectively) and in control receptors

Il lavoratore disabile tra ragionevoli accomodamenti e tutele di sicurezza

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Multiple sclerosis and work: the role of the occupational physicians

poster presentato al convegno internazionale dell'International Commission on Occupational Health sul ruolo del medico competente nei confronti dei lavoratori affetti da sclerosi multipl

Protection of worker with disability: reasonable accomodations

poster presentato all'EAOHP Conference di Londra sul tema dei ragionevoli accomodamenti che il datore di lavoro deve predisporre per il lavoratore disabil

Alcohol consumption in the road transport: the legal blood alcohol limit

poster presentato al convegno internazionale dell'International Commission on Occupational Health sul limite alcolemico per i lavoratori nel settore dei trasport

Le strategie degli organismi sovranazionali ed internazionali sull'alcol e le indicazioni per i luoghi di lavoro

rassegna sulle strategie, i documenti, le best practices elaborate dagli organismi internazionali e sovranazionali per prevenire ed affrontare problematiche legate all'abuso di alcol in relazione al luogo di lavor

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rassegna delle strategie, dei documenti e delle best practices elaborate dagli organismo internazionali e sovranazionali per agevole l'inserimento ed il reinserimento del lavoratore disabil