The Educational Attainment of Looked After Children - Local Authority Pilot Projects : Final Research Report

The aim of the research was to identify interventions that appeared to make the most difference in terms of both the educational experience and outcomes of the looked after children and young people participating in the local authority pilot projects. Data on attendance, exclusions and attainment were collected for a population of more than 600 children and young people. The research also analysed qualitative data, based on interviews with project co-ordinators, professionals, children and young people, and their parents and carers

Recombinant human epoetin beta in the treatment of chemotherapy-related anemia

Anemia is a common complication of systemic anti-cancer treatment. In this context epoetin beta, like other erythropoiesis-stimulating agents (ESAs), has demonstrable efficacy in raising Hb concentration and reducing the requirement for red cell transfusion. Consequently ESA therapy has gained increasing prominence in the management of chemotherapy-related anemia. However, recent trial data have suggested a higher rate of thromboembolic events, enhanced tumor progression and reduced survival in some patients with cancer who receive ESA therapy. In response, regulatory authorities have mandated increasingly restrictive label changes. In light of these new developments we consider the current role of epoetin beta in the management of chemotherapy-related anemia

Tipping Points of Digitisation: The Case of Legal Services

This paper contributes to the literature by challenges the value proposition of digitalisation across three sectors of professional services namely: law, and accounting/finance services. Our study aims to reflect on the knowledge and application of new technologies, deliberating a case for improving the value proposition challenging the existing business models of legal services. The study makes a contribution through a reflection new technologies and business models, through the ‘arcs of integration’. An exploratory research design, embracing an abductive approach, was adopted to new technologies, perceived performance through 224 quantitative data responses. The findings identified the issues professional service firms face, particularly the scope of adoption new technologies and perceived value of digitisation. This research has created a model that impact of legal and financial services. It adds much needed value to the concepts of the value proposition and technology transfer

NuSTAR detection of X-ray heating events in the quiet Sun

The explanation of the coronal heating problem potentially lies in the existence of nanoflares, numerous small-scale heating events occurring across the whole solar disk. In this Letter, we present the first imaging spectroscopy X-ray observations of three quiet Sun flares during the Nuclear Spectroscopic Telescope ARray (NuSTAR) solar campaigns on 2016 July 26 and 2017 March 21, concurrent with the Solar Dynamics Observatory/Atmospheric Imaging Assembly (SDO/AIA) observations. Two of the three events showed time lags of a few minutes between peak X-ray and extreme ultraviolet emissions. Isothermal fits with rather low temperatures in the range 3.2–4.1 MK and emission measures of (0.6–15) × 1044 cm−3 describe their spectra well, resulting in thermal energies in the range (2–6) × 1026 erg. NuSTAR spectra did not show any signs of a nonthermal or higher temperature component. However, as the estimated upper limits of (hidden) nonthermal energy are comparable to the thermal energy estimates, the lack of a nonthermal component in the observed spectra is not a constraining result. The estimated Geostationary Operational Environmental Satellite (GOES) classes from the fitted values of temperature and emission measure fall between 1/1000 and 1/100 A class level, making them eight orders of magnitude fainter in soft X-ray flux than the largest solar flares

Physiology students can use a quality improvement approach to support a safe and efficient medication pathway in geriatric rehabilitation

Peer reviewedPublisher PD

NuSTAR hard X-ray observation of a sub-A class solar flare

We report a NuSTAR observation of a solar microflare, SOL2015-09-01T04. Although it was too faint to be observed by the GOES X-ray Sensor, we estimate the event to be an A0.1 class flare in brightness. This microflare, with only 5 counts per second per detector observed by RHESSI, is fainter than any hard X-ray (HXR) flare in the existing literature. The microflare occurred during a solar pointing by the highly sensitive NuSTAR astrophysical observatory, which used its direct focusing optics to produce detailed HXR microflare spectra and images. The microflare exhibits HXR properties commonly observed in larger flares, including a fast rise and more gradual decay, earlier peak time with higher energy, spatial dimensions similar to the RHESSI microflares, and a high-energy excess beyond an isothermal spectral component during the impulsive phase. The microflare is small in emission measure, temperature, and energy, though not in physical size; observations are consistent with an origin via the interaction of at least two magnetic loops. We estimate the increase in thermal energy at the time of the microflare to be 2.4x10^27 ergs. The observation suggests that flares do indeed scale down to extremely small energies and retain what we customarily think of as "flarelike" properties.Comment: Status: Accepted by the Astrophysical Journal, 2017 July 1