Temperature-dependent transformation of biogas-producing microbial communities points to the increased importance of hydrogenotrophic methanogenesis under thermophilic operation

Stability of biogas production is highly dependent on the microbial community composition of the bioreactors. This composition is basically determined by the nature of biomass substrate and the physical-chemical parameters of the anaerobic digestion. Operational temperature is a major factor in the determination of the anaerobic degradation process. Next-generation sequencing (NGS)-based metagenomic approach was used to monitor the organization and operation of the microbial community throughout an experiment where mesophilic reactors (37. °C) were gradually switched to thermophilic (55. °C) operation. Temperature adaptation resulted in a clearly thermophilic community having a generally decreased complexity compared to the mesophilic system. A temporary destabilization of the system was observed, indicating a lag phase in the community development in response to temperature stress. Increased role of hydrogenotrophic methanogens under thermophilic conditions was shown, as well as considerably elevated levels of Fe-hydrogenases and hydrogen producer bacteria were observed in the thermophilic system

Capsaicin-Sensitive Sensory Nerves Mediate the Cellular and Microvascular Effects of H2S via TRPA1 Receptor Activation and Neuropeptide Release

This study was supported by Hungarian Research Grant BOTKA NN-114458^, by the Hungarian Brain Research Program and National Development Agency KTIA_NAP_13-1-2013-0001, and MTA-PTE NAP B Chronic Pain Research Group, 888819. E. Pintér was supported by János Szentágothai Scholarship (A2-SZJÖ-TOK-13-0149) of the Hungarian National Excellence Program TÁMOP-4.2.4. A/2-11-1- 2012-0001. A. A. Aubdool is supported by the British Heart Foundation PG/12/34/29557. É. Sághy and M. Payrits were supported by Gedeon Richter's Talentum Foundatio

Correlation between Na/K ratio and electron densities in blood samples of breast cancer patients

The main purpose of this study was to investigate the relationship between the electron densities and Na/K ratio which has important role in breast cancer disease. Determinations of sodium and potassium concentrations in blood samples performed with inductive coupled plasma-atomic emission spectrometry. Electron density values of blood samples were determined via ZXCOM. Statistical analyses were performed for electron densities and Na/K ratio including Kolmogorov-Smirnov normality tests, Spearman's rank correlation test and Mann-Whitney U test. It was found that the electron densities significantly differ between control and breast cancer groups. In addition, statistically significant positive correlation was found between the electron density and Na/K ratios in breast cancer group