66 research outputs found

    Effect of Instrumental Polarization with a Half-Wave Plate on the BB-Mode Signal: Prediction and Correction

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    We evaluate the effect of half-wave plate (HWP) imperfections inducing intensity leakage to the measurement of Cosmic Microwave Background (CMB) BB-mode polarization signal with future satellite missions focusing on the tensor-to-scalar ratio rr. The HWP is modeled with the Mueller formalism, and coefficients are decomposed for any incident angle into harmonics of the HWP rotation frequency due to azimuthal angle dependence. Although we use a general formalism, band-averaged matrix coefficients are calculated as an example for a 9-layer sapphire HWP using EM propagation simulations. We perform simulations of multi-detector observations in a band centered at 140\,GHz using \LB instrumental configuration. We show both theoretically and with the simulations that most of the artefacts on Stokes parameter maps are produced by the dipole leakage on BB-modes induced by the fourth harmonics MQI(4f)M^{(4f)}_{QI} and MUI(4f)M^{(4f)}_{UI}. The resulting effect is strongly linked to the spin-2 focal plane scanning cross linking parameters. We develop a maximum likelihood-based method to correct the IP leakage by joint fitting of the Mueller matrix coefficients as well as the Stokes parameter maps. % by modifying the standard map-making procedure. We show that the residual leakage after correction leads to an additional noise limited uncertainty on rr of the order of 10710^{-7}, independently of the value of the Mueller matrix coefficients. We discuss the impact of the monopole signal and the potential coupling with other systematic effects such as gain variations and detector nonlinearities.Comment: 36 pages, 10 figures, submitted to JCA

    Measurement of the solar neutrino energy spectrum at Super-Kamiokande

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    報告番号: 甲14020 ; 学位授与年月日: 1999-03-29 ; 学位の種別: 課程博士 ; 学位の種類: 博士(理学) ; 学位記番号: 博理第3509号 ; 研究科・専攻: 理学系研究科物理学専

    From Structure-Function Analyses to Protein Engineering for Practical Applications of DNA Ligase

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    DNA ligases are indispensable in all living cells and ubiquitous in all organs. DNA ligases are broadly utilized in molecular biology research fields, such as genetic engineering and DNA sequencing technologies. Here we review the utilization of DNA ligases in a variety of in vitro gene manipulations, developed over the past several decades. During this period, fewer protein engineering attempts for DNA ligases have been made, as compared to those for DNA polymerases. We summarize the recent progress in the elucidation of the DNA ligation mechanisms obtained from the tertiary structures solved thus far, in each step of the ligation reaction scheme. We also present some examples of engineered DNA ligases, developed from the viewpoint of their three-dimensional structures
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