Design and implementation of a landslide early warning system

Abstract In this paper all the phases for the realization of the early warning system for the rockslide of Torgiovannetto in Central Italy are described. The landslide consists in a 182,000 m3 rock wedge threatening two roads which are important for local transportation. The present work encompasses all the components of an early warning system, including the geological knowledge, the risk scenarios, the kinematic characterization of the landslide, the choice and installation of the monitoring system, the setting of appropriate alarm levels and the definition of plans of civil protection. The focus is on practical and logistical issues met in all these phases and the counter-measures adopted. At present the system consists in 13 wire extensometers, 1 thermometer, 1 rain gauge and 3 cameras. Should a velocity threshold be exceeded by two or more sensors, the attention level would be entered, causing improved monitoring and surveillance. In case the behavior of the landslide changes and, by using expert judgment and forecasting methods, an imminent failure is hinted, then an alarm is issued and the upper road is closed. This paper can provide ideas and solutions for a landslide early warning system that aims to be simple, flexible, versatile and with a low probability of giving false alarms

Ruptured Left Subclavian Artery Aneurysm in a 41-Year-Old Woman with Neurofibromatosis Type 1

Abstract Introduction Intrinsic lesions of the arterial wall are important manifestations of Neurofibromatosis type 1. Report A 41-year-old woman with Neurofibromatosis type 1, suffering sudden onset of upper back as well as left shoulder and upper chest pain is addressed to our hospital. The contrast-enhanced thoracic computed tomogram demonstrated a huge hematoma due to ruptured left subclavian artery aneurysm treated with endovascular therapy. Discussion A ruptured left subclavian artery is an uncommon but life threatening manifestation in Neurofibromatosis type 1

Combined Finite–Discrete Numerical Modeling of Runout of the Torgiovannetto di Assisi Rockslide in Central Italy

The combined finite–discrete-element method (FDEM) is an advanced and relatively new numerical modeling technique that combines the features of the FEM with those of the discrete-element method. It simulates the transition of brittle geomaterials from continua to discontinua through fracture growth, coalescence, and propagation. With FDEM, it is possible to simulate landslides from triggering to runout and carry out landslide scenario analyses, the results of which can be successively adopted for cost-effective early warning systems. The purpose of this paper is to describe the results of the FDEM simulations of the triggering mechanism and the evolution scenarios of the Torgiovannetto di Assisi rockslide (central Italy), a depleted limestone quarry face where a rock wedge with an approximate volume of 182,000 m3 lies in limit equilibrium conditions, posing relevant issues in terms of civil protection. The results obtained demonstrate that the FDEM is able to realistically simulate the different phases of such a complex slope’s failure as well as to estimate both its runout distances and velocity, key features for landslide risk assessment, and management

Review of ten years of volcano deformations recorded by the ground-based InSAR monitoring system at Stromboli volcano: a tool to mitigate volcano flank dynamics and intense volcanic activity

AbstractStromboli volcano (Southern Italy) is one of the most monitored volcano in the world with a surveillance network that includes a permanently sited ground-based SAR interferometer (GBInSAR). This work is the review of the GBInSAR data gained from the last decade of monitoring activity. The analysis of the entire dataset of GBInSAR measurements allowed the assessment of the deformation field of the northern part of the summit crater area and the Sciara del Fuoco depression. In detail, the main displacements recognized can be related to different factors: 1) the inflation/deflation respectively immediately before and after each new effusive event; 2) the bulging of localized sectors of the volcano involved in the vent opening; 3) the gravitational sliding of the Sciara del Fuoco infill; 4) the movement of lava flows. Accelerations in this sector are related to sheet intrusions, while the possibility of vent opening, associated with small sliding, or catastrophic flank failure are related to highly overpressurized sheets, able to produce high displacement rate in the Sciara del Fuoco.In the summit crater area, the increases in the displacement rate are related to the pressurization of the shallow conduit system, as the consequence of the variation in the magma level (magmastatic pressure) or to the lateral magma migration (lateral conduit expansion or dike intrusion) in response to the increase of the overpressure component. Fluctuations in the displacement rate in the summit crater area can be related to the magma overturning within the conduit, with the increases in displacement rate during the upwelling of less dense magma, while displacement rate decreases as the degassed magma column is pushed out from the conduit (lava flows or overflows). Instead, the decrease in the displacement rate without coeval lava outpouring could be related to the sink of the degassed magma due to density contrast between the gas-poor and the gas-charged magmas. Using the displacement rate in the summit crater area as a proxy for the variation in the pressure condition in conduit (both magmastatic and overpressure components), thresholds for the crises characterized by the occurrence of overflows (eventually associated with major explosions) and flank effusions (eventually associated with paroxysmal explosions) are identified. Small conduit overpressure will produce overflows (sometimes associated with crater-rim collapses), while large magma overpressure will laterally expand the conduit forming NE-SW striking sheets, feeding eruptive vents at the base of the summit crater area and within the Sciara del Fuoco, generating conditions of instability that can evolve into catastrophic collapse of the instable flank

Molecular analysis of Duchenne/Becker muscular dystrophy

n/

Infezione sistemica da Salmonella Arizona: discussione di un raro caso chirurgico.

Salmonella arizona enteritis has been described in patients resident in the southern states of the USA and in Mexico, whereas in Europe it is rarer. The virulence of this bacillus is, however, still little known and we have few descriptions of severe systemic infections, which are all present in patients with immune system impairment. Only two cases have been reported in Italy where the infection has occurred as severe sepsis with the pathogenic agent being isolated in the blood. Here we report what is, on the basis of our knowledge, the third case in Italy of a systemic Salmonella arizona infection

How the First Year of the COVID-19 Pandemic Impacted Patients’ Hospital Admission and Care in the Vascular Surgery Divisions of the Southern Regions of the Italian Peninsula

Background: To investigate the effects of the COVID-19 lockdowns on the vasculopathic population. Methods: The Divisions of Vascular Surgery of the southern Italian peninsula joined this multicenter retrospective study. Each received a 13-point questionnaire investigating the hospitalization rate of vascular patients in the first 11 months of the COVID-19 pandemic and in the preceding 11 months. Results: 27 out of 29 Centers were enrolled. April-December 2020 (7092 patients) vs. 2019 (9161 patients): post-EVAR surveillance, hospitalization for Rutherford category 3 peripheral arterial disease, and asymptomatic carotid stenosis revascularization significantly decreased (1484 (16.2%) vs. 1014 (14.3%), p = 0.0009; 1401 (15.29%) vs. 959 (13.52%), p = 0.0006; and 1558 (17.01%) vs. 934 (13.17%), p < 0.0001, respectively), while admissions for revascularization or major amputations for chronic limb-threatening ischemia and urgent revascularization for symptomatic carotid stenosis significantly increased (1204 (16.98%) vs. 1245 (13.59%), p < 0.0001; 355 (5.01%) vs. 358 (3.91%), p = 0.0007; and 153 (2.16%) vs. 140 (1.53%), p = 0.0009, respectively). Conclusions: The suspension of elective procedures during the COVID-19 pandemic caused a significant reduction in post-EVAR surveillance, and in the hospitalization of asymptomatic carotid stenosis revascularization and Rutherford 3 peripheral arterial disease. Consequentially, we observed a significant increase in admissions for urgent revascularization for symptomatic carotid stenosis, as well as for revascularization or major amputations for chronic limb-threatening ischemia

Cancer data quality and harmonization in Europe: the experience of the BENCHISTA Project – international benchmarking of childhood cancer survival by stage

IntroductionVariation in stage at diagnosis of childhood cancers (CC) may explain differences in survival rates observed across geographical regions. The BENCHISTA project aims to understand these differences and to encourage the application of the Toronto Staging Guidelines (TG) by Population-Based Cancer Registries (PBCRs) to the most common solid paediatric cancers.MethodsPBCRs within and outside Europe were invited to participate and identify all cases of Neuroblastoma, Wilms Tumour, Medulloblastoma, Ewing Sarcoma, Rhabdomyosarcoma and Osteosarcoma diagnosed in a consecutive three-year period (2014-2017) and apply TG at diagnosis. Other non-stage prognostic factors, treatment, progression/recurrence, and cause of death information were collected as optional variables. A minimum of three-year follow-up was required. To standardise TG application by PBCRs, on-line workshops led by six tumour-specific clinical experts were held. To understand the role of data availability and quality, a survey focused on data collection/sharing processes and a quality assurance exercise were generated. To support data harmonization and query resolution a dedicated email and a question-and-answers bank were created.Results67 PBCRs from 28 countries participated and provided a maximally de-personalized, patient-level dataset. For 26 PBCRs, data format and ethical approval obtained by the two sponsoring institutions (UCL and INT) was sufficient for data sharing. 41 participating PBCRs required a Data Transfer Agreement (DTA) to comply with data protection regulations. Due to heterogeneity found in legal aspects, 18 months were spent on finalizing the DTA. The data collection survey was answered by 68 respondents from 63 PBCRs; 44% of them confirmed the ability to re-consult a clinician in cases where stage ascertainment was difficult/uncertain. Of the total participating PBCRs, 75% completed the staging quality assurance exercise, with a median correct answer proportion of 92% [range: 70% (rhabdomyosarcoma) to 100% (Wilms tumour)].ConclusionDifferences in interpretation and processes required to harmonize general data protection regulations across countries were encountered causing delays in data transfer. Despite challenges, the BENCHISTA Project has established a large collaboration between PBCRs and clinicians to collect detailed and standardised TG at a population-level enhancing the understanding of the reasons for variation in overall survival rates for CC, stimulate research and improve national/regional child health plans