A COMPARISON OF METHODS FOR SELECTING PREFERRED SOLUTIONS IN MULTIOBJECTIVE DECISION MAKING

ISBN : 978-94-91216-77-0In multiobjective optimization problems, the identified Pareto Frontiers and Sets often contain too many solutions, which make it difficult for the decision maker to select a preferred alternative. To facilitate the selection task, decision making support tools can be used in different instances of the multiobjective optimization search to introduce preferences on the objectives or to give a condensed representation of the solutions on the Pareto Frontier, so as to offer to the decision maker a manageable picture of the solution alternatives. This paper presents a comparison of some a priori and a posteriori decision making support methods, aimed at aiding the decision maker in the selection of the preferred solutions. The considered methods are compared with respect to their application to a case study concerning the optimization of the test intervals of the components of a safety system of a nuclear power plant. The engine for the multiobjective optimization search is based on genetic algorithms

A comprehensive overview of radioguided surgery using gamma detection probe technology

The concept of radioguided surgery, which was first developed some 60 years ago, involves the use of a radiation detection probe system for the intraoperative detection of radionuclides. The use of gamma detection probe technology in radioguided surgery has tremendously expanded and has evolved into what is now considered an established discipline within the practice of surgery, revolutionizing the surgical management of many malignancies, including breast cancer, melanoma, and colorectal cancer, as well as the surgical management of parathyroid disease. The impact of radioguided surgery on the surgical management of cancer patients includes providing vital and real-time information to the surgeon regarding the location and extent of disease, as well as regarding the assessment of surgical resection margins. Additionally, it has allowed the surgeon to minimize the surgical invasiveness of many diagnostic and therapeutic procedures, while still maintaining maximum benefit to the cancer patient. In the current review, we have attempted to comprehensively evaluate the history, technical aspects, and clinical applications of radioguided surgery using gamma detection probe technology

I-ImaS: intelligent imaging sensors

Conventional x-radiography uniformly irradiates the relevant region of the patient. Across that region, however, there is likely to be significant variation in both the thickness and pathological composition of the tissues present, which means that the x-ray exposure conditions selected, and consequently the image quality achieved, are a compromise. The I-ImaS concept eliminates this compromise by intelligently scanning the patient to identify the important diagnostic features, which are then used to adaptively control the x-ray exposure conditions at each point in the patient. In this way optimal image quality is achieved throughout the region of interest whilst maintaining or reducing the dose. An I-ImaS system has been built under an EU Framework 6 project and has undergone preclinical testing. The system is based upon two rows of sensors controlled via an FPGA based DAQ board. Each row consists of a 160mm ×1 mm linear array of ten scintillator coated 3T CMOS APS devices with 32 μm pixels and a readable array of 520×40 pixels. The first sensor row scans the patient using a fraction of the total radiation dose to produce a preview image, which is then interrogated to identify the optimal exposure conditions at each point in the image. A signal is then sent to control a beam filter mechanism to appropriately moderate x-ray beam intensity at the patient as the second row of sensors follows behind. Tests performed on breast tissue sections found that the contrast-to-noise ratio in over 70% of the images was increased by an average of 15% at an average dose reduction of 9%. The same technology is currently also being applied to baggage scanning for airport security. © 2010 IOP Publishing Ltd and SISSA