COVID-19 and ophthalmology practice at University Hospital “Policlinico Umberto I” in Rome

COVID-19 is a newly defined disease, affecting the respiratory system. It is caused by a novel coronavirus, called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The growing importance of the outbreak led the World Health Organization (WHO) to declare it a public health emergency of international concern on 30 January 2020 and to later officially describe it as a pandemic on 11 March 2020. Italy was the first European country to be heavily impacted by COVID-19, with the number of cases and deaths caused by the virus surging in the months of March and April 2020. Ophthalmologists represent a high-risk category for the spread of the infection, mainly because the examination demands close contact with the patient, exposing the clinician to tear, conjunctival secretions and to aerosol droplets

Effect of dephasing on the current statistics of mesoscopic devices

We investigate the effects of dephasing on the current statistics of mesoscopic conductors with a recently developed statistical model, focusing in particular on mesoscopic cavities and Aharonov-Bohm rings. For such devices, we analyze the influence of an arbitrary degree of decoherence on the cumulants of the current. We recover known results for the limiting cases of fully coherent and totally incoherent transport and are able to obtain detailed information on the intermediate regime of partial coherence for a varying number of open channels. We show that dephasing affects the average current, shot noise, and higher order cumulants in a quantitatively and qualitatively similar way, and that consequently shot noise or higher order cumulants of the current do not provide information on decoherence additional or complementary to what can be already obtained from the average current.Comment: 4 pages, 4 figure

Three Dimensional Visualization and Fractal Analysis of Mosaic Patches in Rat Chimeras: Cell Assortment in Liver, Adrenal Cortex and Cornea

The production of organ parenchyma in a rapid and reproducible manner is critical to normal development. In chimeras produced by the combination of genetically distinguishable tissues, mosaic patterns of cells derived from the combined genotypes can be visualized. These patterns comprise patches of contiguously similar genotypes and are different in different organs but similar in a given organ from individual to individual. Thus, the processes that produce the patterns are regulated and conserved. We have previously established that mosaic patches in multiple tissues are fractal, consistent with an iterative, recursive growth model with simple stereotypical division rules. Fractal dimensions of various tissues are consistent with algorithmic models in which changing a single variable (e.g. daughter cell placement after division) switches the mosaic pattern from islands to stripes of cells. Here we show that the spiral pattern previously observed in mouse cornea can also be visualized in rat chimeras. While it is generally held that the pattern is induced by stem cell division dynamics, there is an unexplained discrepancy in the speed of cellular migration and the emergence of the pattern. We demonstrate in chimeric rat corneas both island and striped patterns exist depending on the age of the animal. The patches that comprise the pattern are fractal, and the fractal dimension changes with the age of the animal and indicates the constraint in patch complexity as the spiral pattern emerges. The spiral patterns are consistent with a loxodrome. Such data are likely to be relevant to growth and cell division in organ systems and will help in understanding how organ parenchyma are generated and maintained from multipotent stem cell populations located in specific topographical locations within the organ. Ultimately, understanding algorithmic growth is likely to be essential in achieving organ regeneration in vivo or in vitro from stem cell populations

Mechanical Systems: Symmetry and Reduction

Reduction theory is concerned with mechanical systems with symmetries. It constructs a lower dimensional reduced space in which associated conservation laws are taken out and symmetries are \factored out" and studies the relation between the dynamics of the given system with the dynamics on the reduced space. This subject is important in many areas, such as stability of relative equilibria, geometric phases and integrable systems

Analysis of shot noise suppression in mesoscopic cavities in a magnetic field

We present a numerical investigation of shot noise suppression in mesoscopic cavities and an intuitive semiclassical explanation of the behavior observed in the presence of an orthogonal magnetic field. In particular, we conclude that the decrease of shot noise for increasing magnetic field is the result of the interplay between the diameter of classical cyclotron orbits and the width of the apertures defining the cavity. Good agreement with published experimental results is obtained, without the need of introducing fitting parameters.Comment: 5 pages, 3 figures, contents changed (final version

Theoretical Analysis of a 2D Metallic/Semiconducting Transition-Metal Dichalcogenide NbS2//WSe2 Hybrid Interface

A first-principles theoretical study of a monolayer-thick lateral heterostructure (LH) joining two different transition metal dichalcogenides, NbS2 and WSe2, is reported. The NbS2//WSe2 LH can be considered a prototypical example of a metal (NbS2)/semiconductor (WSe2) 2D hybrid heterojunction. First, realistic atomistic models of the NbS2//WSe2 LH are generated and validated, its band structure is derived, and it is subjected to a fragment decomposition and electrostatic potential analysis to extract a simple but quantitative model of this interfacial system. Stoichiometric fluctuations models are also investigated and found not to alter the qualitative picture. Then, electron transport simulations are conducted and they are analyzed via band alignment analysis. It is concluded that the NbS2//WSe2 LH appears as a robust seamless in-plane 2D modular junction for potential use in optoelectronic devices going beyond the present miniaturization technology

Non Equilibrium Electronic Distribution in Single Electron Devices

The electronic distribution in devices with sufficiently small diemnsions may not be in thermal equilibrium with their surroundings. Systems where the occupancies of electronic states are solely determined by tunneling processes are analyzed. It is shown that the effective temperature of the device may be higher, or lower, than that of its environment, depending on the applied voltage and the energy dependence of the tunneling rates. The I-V characteristics become asymmetric. Comparison with recent experiments is made

Shot Noise Enhancement in Resonant Tunneling Structures in a Magnetic Field

We have observed that the shot noise of tunnel current, I, in GaSb-AlSb-InAs-AlSb-GaSb double-barrier structure under a magnetic field can exceed 2qI. The measurements were done at T=4K in fields up to 5T parallel to the current. The noise enhancement occurred at each of the several negative-differential conductance regions induced by the tunneling of holes through Landau levels in the InAs quantum well. The amount of the enhancement increased with the strength of the negative conductance and reached values up to 8qI. These results are explained qualitatively by fluctuations of the density of states in the well, but point out the need for a detailed theory of shot noise enhancement in resonant tunneling devices.Comment: 4 pages, RevTex, 3 figure

CUMAS: a seafloor multi-sensor module for volcanic hazard monitoring - First long-term experiment and performance assessment

A seafloor multi-sensor module with real-time data transmission, named CUMAS (Cabled Underwater Module for Acquisition of Seismological data), has been deployed in January 2008 in the Gulf of Pozzuoli, in the Campi Flegrei caldera (southern Italy), which is one of the most active volcanic areas in the world. The sensors installed in CUMAS were selected to monitor a set of signals related to the local seismicity as well as the ground uplift and subsidence of the seafloor that are related to the bradyseismic phenomenon. In particular, together with a broad-band three-component seismometer and a low-frequency hydrophone, a seafloor water-pressure sensor is used to assess the feasibility of measurements of the slow vertical movement of the seafloor (bradyseism). Further sensors are acquired by two embedded Linux computers, namely tilt and heading sensors for the measure of the actual module orientation on the seafloor, and status sensors that monitor the state of health of the vessel (e.g., internal temperature, power absorption, water intrusion). The underwater acquisition systems are linked to a support infrastructure, a floating buoy (elastic beacon), through an electro-mechanical cable with an Ethernet line. The buoy provides the needed power supply thanks to batteries charged by solar panels and a wind- generator. A Wi-Fi antenna on the buoy is used to transmit the seafloor data from the sea surface to the land acquisition centre in the city of Naples. A meteorological station is also mounted on the buoy, to allow the correlation of the air and seafloor data. CUMAS, although based on commercial sensors, relies on an original system for the centralized management of a wide set of geophysical and physical oceanographic sensors, that handles the continuous data acquisition and real-time data transmission. After the installation in the Gulf of Pozzuoli at about 100 m w.d., and after a test period, CUMAS uninterruptedly operated from May 2008 to June 2009, thus providing continuous geophysical data to the Monitoring Center of the Campi Flegrei volcanic areas, managed by the Istituto Nazionale di Geofisica e Vulcanologia. The long-term operational performance of CUMAS is presented here, together with the first results from the analysis of the geophysical long time-series acquired. Examples of the acquired signals, especially geophysical data, will be presented to point out the high quality in term of signal-to-noise ratio. In particular, earthquake recordings obtained from the hydrophone resulted of comparable quality to the seismic data acquired on land by the permanent network, thus demonstrating the suitability of hydrophones to monitor the seismic activity of the caldera