Ronsard, la Fortune et la Providence: deux élégies au sujet de Mary Stuart, reine d’Écosse

Issue d’une tradition antique et médiévale, la Fortune demeure vivace chez les auteurs français du xvie siècle. Mais la lointaine ascendance païenne de ce personnage peut inquiéter, à une époque où les théologiens sont bien méfiants; on sait, par exemple, qu’à Rome Montaigne dut justifier certains aspects des Essais, dont «l’esser ricorso alla parola ‘fortuna’». En général, l’un des points les plus délicats est celui des rapports de la Fortune et de la Providence. Comme nous le verrons, deux ..

GMOS Spectroscopy of SCUBA Galaxies Behind A851

We have identified counterparts to two submillimeter (submm) sources, SMM J09429+4659 and SMM J09431+4700, seen through the core of the z=0.41 cluster Abell 851. We employ deep 1.4-GHz observations and the far-infrared/radio correlation to refine the submm positions and then optical and near-infrared imaging to locate their counterparts. We identify an extremely red counterpart to SMM J09429+4659, while GMOS spectroscopy with Gemini-North shows that the R=23.8 radio source identified with SMM J09431+4700 is a hyperluminous infrared galaxy (L_FIR~1.5x10^13 L_sun) at z=3.35, the highest spectroscopic redshift so far for a galaxy discovered in the submm. The emission line properties of this galaxy are characteristic of a narrow-line Seyfert-1, although the lack of detected X-ray emission in a deep XMM-Newton observation suggests that the bulk of the luminosity of this galaxy is derived from massive star formation. We suggest that active nuclei, and the outflows they engender, may be an important part of the evolution of the brightest submm galaxies at high redshifts.Comment: to appear in the Oct 1 issue of ApJ Letter

Trauma Immediately Preceding REM-Behavior Disorder:A Valuable Prognostic Marker?

Background: The definition of rapid eye movement (REM) sleep behavior disorder (RBD) has varied over the years. Rapid eye movement sleep behavior disorder can be considered isolated or idiopathic or can occur in the context of other disorders, including trauma-associated sleep disorder (TSD) and overlap parasomnia. However, whether trauma in RBD carries any prognostic specificity is currently unknown. Study Objectives: To test the hypothesis that RBD secondary to trauma is less likely to result in the development of neurodegeneration compared to idiopathic RBD (iRBD) without trauma in the general population. Methods: A retrospective cohort study of 122 consecutive RBD patients (103 males) at two tertiary sleep clinics in Europe between 2005 and 2020 was studied. Patients were diagnosed as having iRBD by video polysomnography (vPSG) and had a semi-structured interview at presentation, including specifically eliciting any history of trauma. Patients with secondary RBD to recognized causes were excluded from the study. Patients with iRBD were categorized into three groups according to reported trauma history: (1) No history of trauma, (2) traumatic experience at least 12 months prior to RBD symptom onset, and (3) traumatic experience within 12 months of RBD symptom onset. Idiopathic RBD duration was defined as the interval between estimated onset of RBD symptoms and last hospital visit or death. Follow-up duration was defined as the interval between iRBD diagnosis and last hospital visit or death. Results: In a follow-up period of up to 18 years, no patient who experienced trauma within 12 months preceding their iRBD diagnosis received a diagnosis of a neurodegenerative disorder (n = 35), whereas 38% of patients without trauma within the 12 months of symptom onset developed a neurodegenerative illness. These patients were also significantly more likely to have a family history of α-synucleinopathy or tauopathy. Conclusions: The development of RBD within 12 months of experiencing a traumatic life event, indistinguishable clinically from iRBD, did not lead to phenoconversion to a neurodegenerative disorder even after 18 years (mean follow up 6 years). We suggest that a sub-type of RBD be established and classified as secondary RBD due to trauma. Additionally, we advocate that a thorough psychological and trauma history be undertaken in all patients presenting with dream enactment behaviors (DEB)

Effect of H on the crystalline and magnetic structures of the YCo3-H(D) system. I. YCo3 from neutron powder diffraction and first-principles calculations

This paper reports investigations into the influence of hydrogen on the magnetic properties of the YCo3-H system. We report results on the magnetic structure and magnetic transitions of YCo3 using a combination of neutron powder diffraction measurements and first-principles full potential augmented plane wave + local orbital calculations under the generalized gradient approximation. The ferromagnetic and ferrimagnetic structures are examined on an equal footing. However, we identify that, no matter which structure is used as the starting point, the neutron diffraction data always refines down to the ferrimagnetic structure with the Co2 atoms having antiparallel spins. In the ab initio calculations, the inclusion of spin-orbit coupling is found to be important in the prediction of the correct magnetic ground state. Here, the results suggest that, for zero external field and sufficiently low temperatures, the spin arrangement of YCo3 is ferrimagnetic rather than ferromagnetic as previously believed. The fixed spin moment calculation technique has been employed to understand the two successive field-induced magnetic transitions observed in previous magnetization measurements under increasing ultrahigh magnetic fields. We find that the magnetic transitions start from the ferrimagnetic phase �0.61�B/Co� and terminate with the ferromagnetic phase �1.16�B/Co�, while the spin on the Co2 atoms progressively changes from antiparallel ferrimagnetic to paramagnetic and then to ferromagnetic. Our neutron diffraction measurements, ab initio calculations, and the high field magnetization measurements are thus entirely self-consistent

Expanding Paramedicine in the Community (EPIC): study protocol for a randomized controlled trial.

BackgroundThe incidence of chronic diseases, including diabetes mellitus (DM), heart failure (HF) and chronic obstructive pulmonary disease (COPD) is on the rise. The existing health care system must evolve to meet the growing needs of patients with these chronic diseases and reduce the strain on both acute care and hospital-based health care resources. Paramedics are an allied health care resource consisting of highly-trained practitioners who are comfortable working independently and in collaboration with other resources in the out-of-hospital setting. Expanding the paramedic's scope of practice to include community-based care may decrease the utilization of acute care and hospital-based health care resources by patients with chronic disease.Methods/designThis will be a pragmatic, randomized controlled trial comparing a community paramedic intervention to standard of care for patients with one of three chronic diseases. The objective of the trial is to determine whether community paramedics conducting regular home visits, including health assessments and evidence-based treatments, in partnership with primary care physicians and other community based resources, will decrease the rate of hospitalization and emergency department use for patients with DM, HF and COPD. The primary outcome measure will be the rate of hospitalization at one year. Secondary outcomes will include measures of health system utilization, overall health status, and cost-effectiveness of the intervention over the same time period. Outcome measures will be assessed using both Poisson regression and negative binomial regression analyses to assess the primary outcome.DiscussionThe results of this study will be used to inform decisions around the implementation of community paramedic programs. If successful in preventing hospitalizations, it has the ability to be scaled up to other regions, both nationally and internationally. The methods described in this paper will serve as a basis for future work related to this study.Trial registrationClinicalTrials.gov: NCT02034045. Date: 9 January 2014

Multicolour correlative imaging using phosphor probes

Correlative light and electron microscopy exploits the advantages of optical methods, such as multicolour probes and their use in hydrated live biological samples, to locate functional units, which are then correlated with structural details that can be revealed by the superior resolution of electron microscopes. One difficulty is locating the area imaged by the electron beam in the much larger optical field of view. Multifunctional probes that can be imaged in both modalities and thus register the two images are required. Phosphor materials give cathodoluminescence (CL) optical emissions under electron excitation. Lanthanum phosphate containing thulium or terbium or europium emits narrow bands in the blue, green and red regions of the CL spectrum; they may be synthesised with very uniform-sized crystals in the 10- to 50-nm range. Such crystals can be imaged by CL in the electron microscope, at resolutions limited by the particle size, and with colour discrimination to identify different probes. These materials also give emissions in the optical microscope, by multiphoton excitation. They have been deposited on the surface of glioblastoma cells and imaged by CL. Gadolinium oxysulphide doped with terbium emits green photons by either ultraviolet or electron excitation. Sixty-nanometre crystals of this phosphor have been imaged in the atmospheric scanning electron microscope (JEOL ClairScope). This probe and microscope combination allow correlative imaging in hydrated samples. Phosphor probes should prove to be very useful in correlative light and electron microscopy, as fiducial markers to assist in image registration, and in high/super resolution imaging studies

Evaporation, seepage and water quality management in storage dams: a review of research methods

One of the most significant sources of water wastage in Australia is loss from small storage dams, either by seepage or evaporation. Over much of Australia, evaporative demand routinely exceeds precipitation. This paper outlines first, methodologies and measurement techniques to quantify the rate of evaporative loss from fresh water storages. These encompass high-accuracy water balance monitoring; determination of the validity of alternative estimation equations, in particular the FAO56 Penman- Monteith ETo methodology; and the commencement of CFD modeling to determine a 'dam factor' in relation to practical atmospheric measurement techniques. Second, because the application of chemical monolayers is the only feasible alternative to the high cost of physically covering the storages to retard evaporation, the use of cetyl alcohol-based monolayers is reviewed, and preliminary research on their degradation by photolytic action, by wind break-up and by microbial degradation reported. Similarly, preliminary research on monolayer visualisation techniques for field application is reported; and potential enhancement of monolayers by other chemicals and attendant water quality issues are considered

Group Averaging for de Sitter free fields

Perturbative gravity about global de Sitter space is subject to linearization-stability constraints. Such constraints imply that quantum states of matter fields couple consistently to gravity {\it only} if the matter state has vanishing de Sitter charges; i.e., only if the state is invariant under the symmetries of de Sitter space. As noted by Higuchi, the usual Fock spaces for matter fields contain no de Sitter-invariant states except the vacuum, though a new Hilbert space of de Sitter invariant states can be constructed via so-called group-averaging techniques. We study this construction for free scalar fields of arbitrary positive mass in any dimension, and for linear vector and tensor gauge fields in any dimension. Our main result is to show in each case that group averaging converges for states containing a sufficient number of particles. We consider general $N$-particle states with smooth wavefunctions, though we obtain somewhat stronger results when the wavefunctions are finite linear combinations of de Sitter harmonics. Along the way we obtain explicit expressions for general boost matrix elements in a familiar basis.Comment: 33 pages, 2 figure