Финансирование выплат работникам системы здравоохранения в связи с новой коронавирусной инфекцией

Objective: to conduct an analysis of the channels, the volume of COVID payments to medical workers and assess the preliminary effectiveness of funding for coronavirus health worker payments.Material and methods. Statistical comparative analysis of data in the field of health care funding was carried out. The assessment of changes in the level of wages of medical workers was performed using the index method and the grouping method. Relative indicators of the structure were used to evaluate the distribution of transfers by region. The study was conducted on the basis of open Rosstat data on the salaries of medical workers.Results. The regional distribution of transfers was regulated in 2020 by the Federal Government. The main channel for financing COVID payments to medical workers was the allocation of transfers and subsidies. More than half of the funding was accounted for by transfers for incentive payments to health care workers for fulfilling particularly important works. The largest share of allocated transfers fell on the Moscow Region (5.6% of the total volume of transfers), Nizhny Novgorod Region (5.1%), and Saint Petersburg (5.0%), the lowest – on the Republic of Kalmykia, the Republic of Khakassia, the Amur Region (0.2% each), the Nenets Autonomous District (0.1%). Transfers for incentive payments for special working conditions and additional workload were paid in 2020 in a total of 670 thousand persons. Transfers for incentive payments for fulfilling particularly important works were paid in a total of 363 thousand medical workers and 53 thousand ambulance drivers. An assessment of the effectiveness of financing COVID payments in the form of transfers and subsidies showed that it was largely due to them that the medical workers’ mean salary increased.Conclusion. The distribution of aggregated amounts of transfers between the constituent entities of the Russian Federation was carried out until November 2020 on the basis of the number of persons insured under Compulsory Health Insurance program in a corresponding region. In the early months of fighting the pandemic, the use of this aggregate was appropriate.Цель: провести анализ каналов, объемов COVID-выплат медицинским работникам и оценить предварительную результативность финансирования выплат работникам системы здравоохранения в связи с новой коронавирусной инфекцией.Материал и методы. Проведен статистический сравнительный анализ данных в сфере финансирования здравоохранения. Оценка динамики изменения уровня заработной платы медицинских работников выполнена с помощью индексного метода и метода группировок. Для оценки распределения трансфертов по регионам использованы относительные показатели структуры. Исследование проведено на основе открытых данных Росстата по заработной плате медицинских работников.Результаты. Региональное распределение трансфертов регламентировалось в 2020 г. федеральным правительством. Основным каналом финансирования COVID-выплат медицинским работникам являлось выделение трансфертов и дотаций. Более половины объемов финансирования приходилось на долю трансфертов для стимулирующих выплат медицинским работникам за выполнение особо важных работ (ОВР). Наибольший удельный вес выделенных трансфертов приходился на Московскую обл. (5,6% от общего объема трансфертов), Нижегородскую обл. (5,1%) и г. Санкт-Петербург (5,0%), наименьший – на Республики Калмыкию и Хакасию, Амурскую обл. (по 0,2%), Ненецкий автономный округ (0,1%). Трансферты для стимулирующих выплат за особые условия труда и дополнительную нагрузку были выплачены в 2020 г. в совокупности 670 тыс. чел., за выполнение ОВР – 363 тыс. медицинских работников и 53 тыс. водителей машин скорой медицинской помощи. Оценка результативности финансирования COVID-выплат в форме трансфертов и дотаций показала, что в значительной степени именно за их счет произошел рост средней заработной платы медицинских работников.Заключение. Распределение между субъектами Российской Федерации агрегированных сумм трансфертов осуществлялось до ноября 2020 г. на основе количества лиц, застрахованных по программе обязательного медицинского страхования в соответствующем регионе. В первые месяцы борьбы с пандемией использование данного агрегированного показателя было вполне уместно

Lysosomal acid lipase deficiency – an underestimated cause of hypercholesterolemia in children

Lysosomal acid lipase deficiency (LAL-D) is a rare, progressive, autosomal recessive disease, which develops due to impaired degradation and subsequent intra-lysosomal accumulation of triglycerides and cholesterol esters causing dyslipidemia. The clinical manifestations of the disease presumably depend on the residual activity of the enzyme, lysosomal acid lipase. A profound deficiency of the enzyme known as Wolman’s disease has an onset in the first 6 months of life. The disease reveals itself by dyspeptic disorders in the form of vomiting and diarrhea, lack of weight gain, hepatosplenomegaly, and adrenal calcification. If the Wolman’s disease is not treated, children die within the first 6 months as a result of exhaustion caused by malabsorption syndrome combined with progressive deterioration of liver and adrenal glands. Partial deficiency of lysosomal acid lipase manifests itself at a later age and is called cholesterol ester storage disease. Its clinical presentations include hepatosplenomegaly, elevated transaminases, hypercholesterolemia, and, in some cases, hypertriglyceridemia. Liver failure is the main cause of death in the natural course of cholesterol ester storage disease. Delayed diagnosis of the disease leads to its progression causing irreversible liver damage. The implementation of mass screening programs with the determination of cholesterol levels in childhood is critical to identifying asymptomatic patients.The article presents a clinical case of a patient aged 3 years. The molecular genetic testing showed a mutation in exon 8 of the LIPA gene: NM_000235.3:c.894G>A synonymous variant in the homozygous state. It was also found that both parents of the girl had this type of mutation in the heterozygous state. The patient was prescribed sebelipase alfa in a dose of 1 mg/kg once every 14 days. The treatment was well tolerated. Due to the early verification of the diagnosis and timely pathogenetic therapy, the prognosis of the course of LAL-D, the duration and quality of life of the child were considered to be favourable.Raising the awareness of doctors along with the introduction of effective screening programs for the timely detection of dyslipidemia in children contributes to timely diagnosis and early initiation of pathogenetic therapy, which can increase the life expectancy of patients with lysosomal acid lipase deficiency and improve their quality of life

Typology of the headline complex elements in corporate university media (based on newspapers “Ural Federal” and “Gaceta UNAM”)

Исследование направлено на составление типологии элементов заголовочного комплекса в корпоративных вузовских изданиях. Материалом исследования послужили свыше 800 дотекстовых и внутритекстовых высказываний в изданиях «Уральский федеральный» и «Gaceta UNAM». Результаты демонстрируют наличие в обеих газетах четырех основных компонентов заголовочной системы, а именно заголовков, подзаголовков/надзаголовков, рубрик и вставок. Сравнение их подтипов свидетельствует о разнице в образах СМИ. «Уральский федеральный» стремится к сочетанию информативных и эмотивных составляющих заголовочной системы, в то время как UNAM подходит к их поиску и организации исключительно формально, ориентируясь на полноту содержания. Следовательно, одни и те же элементы можно модифицировать и по-разному применять в университетских СМИ в соответствии с их позиционированием.The research goal is to assemble the typology of headline complex elements in corporate university media. The study is based on 800 pretext and intertext statements in the “Ural Federal” and “Gaceta UNAM” issues. The results depict that both newspapers contain 4 main headline complex elements such as headlines, subheadings, columns and text insertions. The comparison to their subtypes indicates the difference between the images of media. “Ural Federal” intends to combine the informative and the emotional components of the headline system, whereas “Gaceta UNAM” has a merely formal approach to finding and organizing them and focuses on the completeness of the content. Consequently, the same elements can be modified and applied differently in university media according to their positioning

Geoecological validation of mechanisms and parameters of physical-chemical processes facilitating the in-depth processing of complex suphide ores and mining wastes

Abstract. The advisability of processing copper-nickel ore dressing tailings of current production has been substantiated. The optimal parameters of metal leaching with sulphuric acid have been determined. In laboratory experiments the geotechnological extraction of non-ferrous metals from a leaching layer representing a tailing material of fraction +0.063 mm has been studied. When investigating the geotechnological processes of nonferrous metal extraction on the basis of two copper-zinc ore deposits located in the Urals, the authors have come to the conclusion that heap leaching is of little use for the ores of the Letneye deposit. Leaching results for the Yaman-Kasy ore have shown more promise. Аннотация. Показана целесообразность переработки хвостов обогащения медно-никелевых руд текущего производства. Определены оптимальные параметры сернокислотного выщелачивания металлов. В лабораторных условиях исследовано геотехнологическое извлечение цветных металлов из выщелачиваемого слоя, подготовленного из хвостов фракции +0.063 мм. Изучение геотехнологических процессов извлечения цветных металлов из медно-цинковых руд двух месторождений Урала показало, что руды месторождения Летнего малоприемлемы для кучного выщелачивания. Существенно лучшие результаты получены при выщелачивании руды месторождения Яман-Касы

Эластичные наполнители - продукты вторичной переработки резин, получаемые методом высокотемпературного сдвигового измельчения

In this article matters of investigation of basic physical, chemical and technical properties of a product of recycling rubber by means of high-temperature shift crushing deformation are considered.В работе рассмотрены вопросы, связанные с изучением основных физико-химических и технических свойств продукта вторичной переработки резины, получаемого методом высокотемпературного сдвигового измельчения (ВСИ), на основе отработанных шин и резинотехнических изделий

Mining and validating grape (Vitis L.) ESTs to develop EST-SSR markers for genotyping and mapping

Grape expressed sequence tags (ESTs) are a new resource for developing simple sequence repeat (SSR) functional markers for genotyping and genetic mapping. An integrated pipeline including several computational tools for SSR identification and functional annotation was developed to identify 6,447 EST-SSR sequences from a total collection of 215,609 grape ESTs retrieved from NCBI. The 6,447 EST-SSRs were further reduced to 1,701 non-redundant sequences via clustering analysis, and 1,037 of them were successfully designed with primer pairs flanking the SSR motifs. From them, 150 pairs of primers were randomly selected for PCR amplification, polymorphism and heterozygosity analysis in V. vinifera cvs. Riesling and Cabernet Sauvignon, and V. rotundifolia (muscadine grape) cvs. Summit and Noble, and 145 pairs of these primers yielded PCR products. Pairwise comparisons of loci between the parents Riesling and Cabernet Sauvignon showed that 72 were homozygous in both cultivars, while 70 loci were heterozygous in at least one cultivar of the two. Muscadine parents Noble and Summit had 90 homozygous SSR loci in both parents and contained 50 heterozygous loci in at least one of the two. These EST-SSR functional markers are a useful addition for grape genotyping and genome mapping

The influence of supplementary lighting sources on agro-biological performance in greenhouse-grown cucumbers

The paper presents the research of the influence of supplementary lighting sources on growth and yielding capacity of cucumber hybrids. The experiment was carried out in 2020-2021 in commercial greenhouses. Two sources of supplementary lighting were studied (option 1 – high-pressure sodium arc reflector lamps (SRL) “super” (Reflux), option 2 – LED-lamps (Phillips) on two cucumber hybrids: F1 Meva and F1 Svyatogor. The present research revealed statistically significant influence of factor B (source of supplementary lighting) on the overall crop productivity. To obtain the maximal yield (Meva F1 – 20,86 kg/m 2 , Svyatogor F1 – 18,21 kg/m 2 ), we recommend using LED-lamps as supplementary lighting sources