25 research outputs found
Mathematical model of diagnostics of perinatal damage of the central nervous system in infants in the neonatal period
Questions of relevance and timeliness of diagnostics of perinatal disturbances of the central nervous system in newborns are considered in the article. Research objective was to determine the reliable recognition of the development of newborn encephalopathy at the age of the first two weeks of life according to neurological examination and neurosonography parameters with Doppler study of cerebral vessels. Features of the neurology status and data of ultrasonic examination of brain with Doppler study of cerebral vessels in 58 newborns with pathology of the nervous system and 23 healthy newborns are investigated. 10 sings of the neurological status and 10 parameters of ultrasonic examination are analyzed. By results of the obtained findings, prognostic rule is developed, governed by application of discriminant analysis of the studied signs, allowing to diagnose encephalopathy in newborn with sensitivity and specificity of 95% in the first week of life. Its application promotes timely identification and the beginning of therapy at infants from risk group of development of severe neurological dysfunction and preventing the growth of disability among infants. © 2017 Team of Authors
Clinical manifestations of the onset and diagnostic problems in children with moyamoya disease
Moyamoya disease in children is a rarely diagnosed entity. Frequent headache is the first symptom of the disease. Headache associated with moya-moya disease (HAMD) is a separated entity reported in the literature. Variants of onset, a spectrum of primary diagnoses and diagnosis verification rate of moyamoya disease in 7 children are presented. A clinical case of moya-moya disease in a 9-year boy, who was primarily diagnosed with migraine with aura, is reported. The results presented by the authors as well as literature data indicate the necessity of using magnetic-resonance angiography in children with headache attacks and focal neurologic symptoms to identify this progressive vascular pathology and timely recommend a surgical treatment. © 2016, Media Sphera. All rights reserved
Irreversible Aging Dynamics and Generic Phase Behavior of Aqueous Suspensions of Laponite
In this work we study the aging behavior of aqueous suspension of Laponite
having 2.8 weight % concentration using rheological tools. At various salt
concentration all the samples demonstrate orientational order when observed
using crossed polarizers. In rheological experiments we observe inherent
irreversibility in the aging dynamics which forces the system not to rejuvenate
to the same state in the shear melting experiment carried out at a later date
since preparation. The extensive rheological experiments carried out as a
function of time elapsed since preparation demonstrate the self similar trend
in the aging behavior irrespective of the concentration of salt. We observe
that the exploration of the low energy states as a function of aging time is
only kinetically affected by the presence of salt. We estimate that the energy
barrier to attain the low energy states decreases linearly with increase in the
concentration of salt. The observed superposition of all the elapsed time and
the salt concentration dependent data suggests that the aging that occurs in
low salt concentration systems over a very long period is qualitatively similar
to the aging behavior observed in systems with high salt concentration over a
shorter period.Comment: 27 pages, 8 figures. Langmuir, in pres
Predictors of epilepsy in children after ischemic stroke
Objective. To determine clinical/instrumental predictors of symptomatic epilepsy after ischemic stroke in children. Material and methods. One hundred and thirty-six patients, aged 0-15 years, with the diagnosis of ischemic stroke (ICD-10 I63.0-I63.9) were examined. The duration of the study was 18 months - 12 years. Patients were stratified into post-stroke (n=22) and control (n=114) groups, the latter included patients without epilepsy regardless of the presence of convulsive seizures in the acute stage of stroke. Predictors were determined based on EEG and characteristics of convulsive syndrome in the acute stage of stroke. Results and conclusion. The following prognostic criteria were found: generalized type of seizures, focal type of seizures with secondary generalization, epileptiform (peak and/or peak-wave) activity, focal character of epileptiform activity, generalized type of seizures in the combination with slow wave background activity on EEG, generalized type of seizures in the combination with slow wave activity and disorganized activity on EEG. © 2016, Media Sphera. All Rights Reserved
Controlling Clusters of Colloidal Platelets:The Effects of Edge and Face Surface Chemistries on the Behaviour of Montmorillonite Suspensions
MATHEMATICAL MODEL OF DIAGNOSTICS OF PERINATAL DAMAGE OF THE CENTRAL NERVOUS SYSTEM IN INFANTS IN THE NEONATAL PERIOD
Questions of relevance and timeliness of diagnostics of perinatal disturbances of the central nervous system in newborns are considered in the article. Research objective was to determine the reliable recognition of the development of newborn encephalopathy at the age of the first two weeks of life according to neurological examination and neurosonography parameters with Doppler study of cerebral vessels. Features of the neurology status and data of ultrasonic examination of brain with Doppler study of cerebral vessels in 58 newborns with pathology of the nervous system and 23 healthy newborns are investigated. 10 sings of the neurological status and 10 parameters of ultrasonic examination are analyzed. By results of the obtained findings, prognostic rule is developed, governed by application of discriminant analysis of the studied signs, allowing to diagnose encephalopathy in newborn with sensitivity and specificity of 95% in the first week of life. Its application promotes timely identification and the beginning of therapy at infants from risk group of development of severe neurological dysfunction and preventing the growth of disability among infants
SOMATIC COMORBID ITY AND DE VELOPIN G EPILEPSY IN CHILDREN AFTER A SINGLE SEI ZURE
Aim – to study chronic somatic comorbidity as a possible predictor of epilepsy in children after a single seizure.Materials and methods. Based on the follow-up results, 279 cases were studied and compared: the study group – epilepsy – included 166 children with two or more seizures developed at least 24 hours after the first seizure; the control group – 113 children with a single seizure that remained isolated for the subsequent three years.Results. We found that at the time of the first (single) attack, the background of chronic ocular morbidity (myopia, hypermetropia, optic nerve atrophy, retinal dystrophy) was significantly more common among children in the control group as compared with the confirmed epilepsy group where cardiovascular disorders prevailed. Other concomitant diseases had no statistically significant correlations with the occurrence of epilepsy after a single seizure.Conclusion. Diagnosis of somatic comorbidity in children with a single seizure may be a prognostic factor of subsequent epilepsy
THE PARENTS OF CHILDREN WITH EPILEPSY EMOTIONAL STATUS
Purpose – to study mental and emotional status of parents raising children with epilepsy.Materials and methods. The level of mental and emotional state in 23 parents in families where children with epilepsy are raising was studied. Control group consisted 29 parents raising healthy children. The following questionnaires were used in our study:Torontoalexithimia scale (TAS) and the assessment of the quality of life by SF-36 questionnaire.Results. Parents of children with epilepsy have showed a higher score on a scale of alexithimia and a higher chance of having an increased or high score on this test compared with parents of healthy children. Parents of children with epilepsy also have lower rates of almost all scales of SF-36, and a statistically significant lower score on the total mental health component.Conclusion. The parents of children with epilepsy mental and emotional state is exposed to disorders and this fact need to be considered when developing treatment tactics of pediatric patients with epilepsy