ВЛИЯНИЕ СРЕДЫ ТЕРМООБРАБОТКИ НА СТРУКТУРНЫЕ ПАРАМЕТРЫ ТОНКИХ ПЛЕНОК NiO

Nickel oxide NiO is a light-plane antiferromagnet of the second type (S = 1) with a nickel temperature TN = 523 K. The crystal structure of NiO belongs to the NaCl type (Fm-3m spatial group) unit cell parameter a = 0.4182 nm [1]. Thin films of nickel oxide are of great interest for modern antiferrom.Работа выполнена в рамках государственного задания МИНОБРНАУКИ России (тема «Функция», номер госрегистрации 122021000035–6)

INFLUENCE OF ANNEALING TEMPERATURE ON THE PHASE COMPOSITION OF α-Fe2O3 THIN FILMS

The phase composition of hematite α-Fe2O3 thin films with the thickness of 100 nm on the c-Al2O3 substrates was studied. The dependence of the lattice parameter c on the annealing temperature was determined

Effects of Neurexan® on the stress-induced activity of the anterior cingulate cortex

Background: Two areas of importance in stress reaction are the anterior cingulated cortex (ACC) and the Amygdala. Previous studies showed that especially the dorsal ACC (dACC) influences the generation of autonomic arousal (Critchley et al., 2003). It was also found that the dACC is activated under cognitive stress (Falkenbeg et al., 2012). Thus, the dACC seems to be an important area controlling stress reactivity. Neurexan®, a medicinal product sold over the counter (OTC), contains four ingredients, Passiflora incarnata (passionflower), Avena sativa (oats), Coffea arabica (coffee) and Zincum isovalerianicum (zinc valerianate). Neurexan® has been investigated in patients with symptoms related to acute stress, nervousness/restlessness, and insomnia. The underlying neuronal mechanisms that lead to the reduction of those symptoms are less clear. In this study we explore whether Neurexan® induces changes in the activation of dACC and associated areas during a stress task. Method: Thirty-nine healthy male volunteers participated in a randomized, placebo-controlled, double-blind, two-period-crossover trial. The effects of treatment were measured after a single dose of Neurexan or placebo by 3 Tesla fMRI. The stress response was induced using the ScanSTRESS (Streit et al., 2014), which uses arithmetic tasks as well as mental rotation tasks. Additionally the stress response was measured by saliva cortisol concentration and visual analogue scales (VAS) for nervousness and anxiety. Results: After correcting for multiple testing in the region of interest (right dACC) paired t-test analysis showed a significant activation cluster (peak level p=0.027, FWE-corrected) in rotation stress condition as compared to stress control. Stress induced activity in the right dACC was reduced by Neurexan treatment as compared to placebo. No effect in dACC was found for arithmetics conditions. Conclusion: The intake of single dose of Neurexan® significantly reduces right dACC activation during psychosocial stress compared to the intake of placebo

Evidence for modulation of EEG microstate sequence by vigilance level

The momentary global functional state of the brain is reflected in its electric field configuration and cluster analytical approaches have consistently shown four configurations, referred to as EEG microstate classes A to D. Changes in microstate parameters are associated with a number of neuropsychiatric disorders, task performance, and mental state establishing their relevance for cognition. However, the common practice to use eye-closed resting state data to assess the temporal dynamics of microstate parameters might induce systematic confounds related to vigilance levels. Here, we studied the dynamics of microstate parameters in two independent data sets and showed that the parameters of microstates are strongly associated with vigilance level assessed both by EEG power analysis and fMRI global signal. We found that the duration and contribution of microstate class C, as well as transition probabilities towards microstate class C were positively associated with vigilance, whereas the sign was reversed for microstate classes A and B. Furthermore, in looking for the origins of the correspondence between microstates and vigilance level, we found Granger-causal effects of vigilance levels on microstate sequence parameters. Collectively, our findings suggest that duration and occurrence of microstates have a different origin and possibly reflect different physiological processes. Finally, our findings indicate the need for taking vigilance levels into consideration in resting-sate EEG investigations