Immunocytochemical localization of casein kinase II during interphase and mitosis

We have developed specific antibodies to synthetic peptide antigens that react with the individual subunits of casein kinase II (CKII). Using these antibodies, we studied the localization of CKII in asynchronous HeLa cells by immunofluorescence and immunoelectron microscopy. Further studies were done on HeLa cells arrested at the G1/S transition by hydroxyurea treatment. Our results indicate that the CKII alpha and beta subunits are localized in the cytoplasm during interphase and are distributed throughout the cell during mitosis. Further electron microscopic investigation revealed that CKII alpha subunit is associated with spindle fibers during metaphase and anaphase. In contrast, the CKII alpha' subunit is localized in the nucleus during G1 and in the cytoplasm during S. Taken together, our results suggest that CKII may play significant roles in cell division control by shifting its localization between the cytoplasm and nucleus

Confirmation of Parity Violation in the Gamma Decay of 180Hfm^{180}Hf^{m}

This paper reports measurements using the technique of On Line Nuclear Orientation (OLNO) which reexamine the gamma decay of isomeric $^{\rm 180}$Hf$^{\rm m}$ and specifically the 501 keV 8$^{\rm -}$ -- 6$^{\rm +}$ transition. The irregular admixture of E2 to M2/E3 multipolarity in this transition, deduced from the forward-backward asymmetry of its angular distribution, has for decades stood as the prime evidence for parity mixing in nuclear states. The experiment, based on ion implantation of the newly developed mass-separated $^{\rm 180}$Hf$^{\rm m}$ beam at ISOLDE, CERN into an iron foil maintained at millikelvin temperatures, produces higher degrees of polarization than were achieved in previous studies of this system. The value found for the E2/M2 mixing ratio, $\epsilon$ = -0.0324(16)(17), is in close agreement with the previous published average value $\epsilon$ = - 0.030(2), in full confirmation of the presence of the irregular E2 admixture in the 501 keV transition. The temperature dependence of the forward-backward asymmetry has been measured over a more extended range of nuclear polarization than previously possible, giving further evidence for parity mixing of the 8$^{\rm -}$ and 8$^{\rm +}$ levels and the deduced E2/M2 mixing ratio.Comment: 28 pages, 9 figures, accepted for publication in Physical Review

Self-interacting Elko dark matter with an axis of locality

This communication is a natural and nontrivial continuation of the 2005 work of Ahluwalia and Grumiller on Elko. Here we report that Elko breaks Lorentz symmetry in a rather subtle and unexpected way by containing a `hidden' preferred direction. Along this preferred direction, a quantum field based on Elko enjoys locality. In the form reported here, Elko offers a mass dimension one fermionic dark matter with a quartic self-interaction and a preferred axis of locality. The locality result crucially depends on a judicious choice of phases.Comment: 14 pages (RevTex

Measurement of quasi-elastic 12C(p,2p) scattering at high momentum transfer

We measured the high-momentum quasi-elastic 12C(p,2p) reaction (at center of mass angle near 90 degrees) for 6 and 7.5 GeV/c incident protons. The three-momentum components of both final state protons were measured and the missing energy and momentum of the target proton in the nucleus were determined. The validity of the quasi-elastic picture was verified up to Fermi momenta of about 450 MeV/c, where it might be questionable. Transverse and longitudinal Fermi momentum distributions of the target proton were measured and compared to independent particle models which do not reproduce the large momentum tails. We also observed that the transverse Fermi distribution gets wider as the longitudinal component increases in the beam direction, in contrast to a simple Fermi gas model.Comment: 4 pages including 3 figure

Alternative Signature of TeV Strings

In string theory, it is well known that any hard scattering amplitude inevitably suffers exponential suppression. We demonstrate that, if the string scale is M_s < 2TeV, this intrinsically stringy behavior leads to a dramatic reduction in the QCD jet production rate with very high transverse momenta p_T > 2TeV at LHC. This suppression is sufficient to be observed in the first year of low-luminosity running. Our prediction is based on the universal behavior of string theory, and therefore is qualitatively model-independent. This signature is alternative and complementary to conventional ones such as Regge resonance (or string ball/black hole) production.Comment: a note added; version to appear in Phys. Rev. D; 11 pages, 1 eps figure, LaTeX2e; BibTeX with utphys style use

Noncyclic geometric phase for neutrino oscillation

We provide explicit formulae for the noncyclic geometric phases or Pancharatnam phases of neutrino oscillations. Since Pancharatnam phase is a generalization of the Berry phase, our results generalize the previous findings for Berry phase in a recent paper [Phys. Lett. B, 466 (1999) 262]. Unlike the Berry phase, the noncyclic geometric phase offers distinctive advantage in terms of measurement and prediction. In particular, for three-flavor mixing, our explicit formula offers an alternative means of determining the CP-violating phase. Our results can also be extended easily to explore geometric phase associated with neutron-antineutron oscillations

On the phenomenology of a Z' coupling only to third-family fermions

The phenomenology of an additional U(1) neutral gauge boson Z' coupled to the third family of fermions is discussed. One might expect such a particle to contribute to processes where taus, b and t quarks are produced. Precision data from LEP1 put severe constraints on the mixing and heavy-boson mass. We find that the effects of such a particle could not be observed at hadronic colliders, be it at the Tevatron or the LHC, because of the QCD background. At LEP2 and future e^+e^- linear colliders, one could instead hope to observe such effects, in particular for b\bar b final states.Comment: 36 pages, LaTeX, including 12 figure