Comparative study of the reproduction and the fattening performance of Creole and Large White pigs in Guadeloupe

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A Phase I/II Study of a 72-h Continuous Infusion of Etoposide in Advanced Soft Tissue Sarcoma

Purpose. The study was performed to assess the antitumour activity and toxicity of a 72-h continuous infusion of single-agent etoposide as second-line treatment for patients with locally advanced or metastatic soft tissue sarcoma (STS), following reports of substantial activity using this schedule of etoposide administration as first-line treatment in combination with ifosfamide

Hypercontractivity on the qq-Araki-Woods algebras

Extending a work of Carlen and Lieb, Biane has obtained the optimal hypercontractivity of the $q$-Ornstein-Uhlenbeck semigroup on the $q$-deformation of the free group algebra. In this note, we look for an extension of this result to the type III situation, that is for the $q$-Araki-Woods algebras. We show that hypercontractivity from $L^p$ to $L^2$ can occur if and only if the generator of the deformation is bounded.Comment: 17 page

Comprehensive Characterization of Mesenchymal Stem Cells from Human Placenta and Fetal Membrane and Their Response to Osteoactivin Stimulation

Mesenchymal stem cells (MSCs) are the most promising seed cells for cell therapy and can be isolated from various sources of human adult tissues such as bone marrow (BM-MSC) and adipose tissue. However, cells from these tissues must be obtained through invasive procedures. We, therefore, characterized MSCs isolated from fresh placenta (Pl-MSC) and fetal membrane (Mb-MSC) through morphological and fluorescent-activated cell sorting (FACS). MSC frequency is higher in membrane than placenta (2.14%  ± 0.65 versus 15.67%  ± 0.29%). Pl/Mb-MSCs in vitro expansion potential was significantly higher than BM-MSCs. We demonstrated that one of the MSC-specific marker is sufficient for MSC isolation and that culture in specific media is the optimal way for selecting very homogenous MSC population. These MSCs could be differentiated into mesodermal cells expressing cell markers and cytologic staining consistent with mature osteoblasts and adipocytes. Transcriptomic analysis and cytokine arrays demonstrated broad similarity between placenta- and membrane-derived MSCs and only discrete differences with BM-MSCs with enrichment of networks involved in bone differentiation. Pl/Mb-MSCs displayed higher osteogenic differentiation potential than BM-MSC when their response to osteoactivin was evaluated. Fetal-tissue-derived mesenchymal cells may, therefore, be considered as a major source of MSCs to reach clinical scale banking in particular for bone regeneration

A note on the Mittag–Leffler condition for Bredon-modules

In this note we show the Bredon-analogue of a result by Emmanouil and Talelli, which gives a criterion when the homological and cohomological dimensions of a countable group $G$ agree. We also present some applications to groups of Bredon-homological dimension $1$.Comment: 10 page