226 research outputs found

    THE INFLUENCE OF PHYSICAL METHODS OF VEGETABLES PROCESSING ON THE QUALITY OF FROZEN PRODUCTS

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    The indicators of quality and microbiological safety of frozen vegetable semi-finished products (for example, cut beet) processed in a microwave field for subsequent storage for 18 months at a temperature of minus 20Β±2Β Β°C. Treatment with a microwave field was carried out under the following conditions: power 600Β W and duration 5Β min (180 kJ); power 1000Β W and duration 4 min (240 kJ). It is established that treatment in the microwave field contributes to the preservation of consumer qualities of the product (total solids content, mass fraction of soluble solids, bound moisture content, microbiological effect) in the process of long-term low-temperature storage.The indicators of quality and microbiological safety of frozen vegetable semi-finished products (for example, cut beet) processed in a microwave field for subsequent storage for 18 months at a temperature of minus 20Β±2Β Β°C. Treatment with a microwave field was carried out under the following conditions: power 600Β W and duration 5Β min (180 kJ); power 1000Β W and duration 4 min (240 kJ). It is established that treatment in the microwave field contributes to the preservation of consumer qualities of the product (total solids content, mass fraction of soluble solids, bound moisture content, microbiological effect) in the process of long-term low-temperature storage

    El moderno sistema de tributaciΓ³n de los bienes inmuebles

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    Taxation has long been an integral part of the functioning of the state, and if earlier the so-called β€œtaxes” were used exclusively for the ruling elite and the bureaucratic apparatus, today taxes, forming the state budget revenue item, are subsequently redistributed to support programs various spheres of society, be it medicine, education, science, etc. The article is devoted to the study of the modern system of taxation of real estate, in particular, the specific features of real estate as objects of taxation, the main types of property taxes, regulatory legal acts in the field of taxation, as well as the advantages and disadvantages of the tax structure of the Russian Federation.Los impuestos han sido durante mucho tiempo una parte integral del funcionamiento del estado, y si antes los llamados Β«impuestosΒ» se usaban exclusivamente para la Γ©lite gobernante y el aparato burocrΓ‘tico, hoy los impuestos, que forman la partida de ingresos del presupuesto estatal, se redistribuyen posteriormente a programas de apoyo en diversas esferas de la sociedad, ya sea medicina, educaciΓ³n, ciencia, etc. El artΓ­culo estΓ‘ dedicado al estudio del sistema moderno de tributaciΓ³n de bienes inmuebles, en particular, las caracterΓ­sticas especΓ­ficas de los bienes inmuebles como objetos impositivos, los principales tipos de impuestos a la propiedad, actos legales regulatorios en el campo de los impuestos, asΓ­ como las ventajas y desventajas de la estructura tributaria de la FederaciΓ³n de Rusia

    The Categories of Chronotope and Tonality in a Literary Translation: Homothematic Aspect

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    Π‘Ρ‚Π°Ρ‚ΡŒΡ поступила Π² Ρ€Π΅Π΄Π°ΠΊΡ†ΠΈΡŽ 30.12.2021 Π³.Π‘Ρ‚Π°Ρ‚ΡŒΡ посвящСна Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ΅ Ρ‚Π΅Ρ€ΠΌΠΈΠ½Π° «омотСмия», ΠΏΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½Π½ΠΎΠ³ΠΎ Π² ΡΡ‚Π°Ρ‚ΡŒΡΡ… Π’. Н. ΠœΠ°Ρ€ΠΎΠ²Π° 2015–2020 Π³Π³., Π² лингвотСкстовом аспСктС. Π’ философском смыслС омотСмия Π΅ΡΡ‚ΡŒ согласованиС Π² тСкстС Ρ€Π°Π·Π½Ρ‹Ρ… эпистСмичСских ΡƒΡ€ΠΎΠ²Π½Π΅ΠΉ; с ΠΏΠΎΠ·ΠΈΡ†ΠΈΠΉ ΠΆΠ΅ лингвистики тСкста это Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡ‚ΡŒ выраТСния ΠΎΠ΄Π½ΠΎΠΉ ΠΊΠ°Ρ‚Π΅Π³ΠΎΡ€ΠΈΠΈ срСдствами Ρ€Π°Π·Π½Ρ‹Ρ… языковых ΡƒΡ€ΠΎΠ²Π½Π΅ΠΉ. На ΠΏΡ€ΠΈΠΌΠ΅Ρ€Π΅ ΠΎΠ±ΡŠΠ΅ΠΌΠ½Ρ‹Ρ… структур-сСток «топос-Ρ‚Π΅ΠΌΡ‹Β» (Ρ‚Π΅ΠΌΡ‹-Ρ…Ρ€ΠΎΠ½ΠΎΡ‚ΠΎΠΏΠ°) ΠΈ «тропос-Ρ‚Π΅ΠΌΡ‹Β» (Ρ‚Π΅ΠΌΡ‹-Ρ‚ΠΎΠ½Π°Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ) Π² пьСсС Π’. Уильямса Β«Π’Ρ€Π°ΠΌΠ²Π°ΠΉ β€œΠ–Π΅Π»Π°Π½ΠΈΠ΅β€Β» ΠΏΠΎΠΊΠ°Π·Π°Π½Π° омотСмия описания обстановки, выявлСны основныС спСцифичСскиС особСнности русского ΠΏΠ΅Ρ€Π΅Π²ΠΎΠ΄Π° Π’. НСдСлина Π² сопоставлСнии с английским ΠΎΡ€ΠΈΠ³ΠΈΠ½Π°Π»ΠΎΠΌ.The article is focused on homothemy term development, suggested by V. N. Marov in his works of 2015–2020 referring to the linguotextual aspect. In the philosophical sense, homothemy is the agreement of different epistemic levels in the text; within text linguistics, it is the ability of one category to be expressed by means of different language levels. On the example of grid structures β€œtopos-theme” (chronotope as a theme) and Β«tropos-themesΒ» (tonality as a theme) in the play β€œA Streetcar Named Desire” by T. Williams, the homothemy of the surroundings description is shown, and the main specific features of the Russian translation by V. Nedelin are revealed as compared to the English original

    Manifestation of systemic toxicity in rats after a short-time inhalation of lead oxide nanoparticles

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    Outbred female rats were exposed to inhalation of lead oxide nanoparticle aerosol produced right then and there at a concentration of 1.30 Β± 0.10 mg/m3 during 5 days for 4 h a day in a nose-only setup. A control group of rats were sham-exposed in parallel under similar conditions. Even this short-time exposure of a relatively low level was associated with nanoparticles retention demonstrable by transmission electron microscopy in the lungs and the olfactory brain. Some impairments were found in the organism’s status in the exposed group, some of which might be considered lead-specific toxicological outcomes (in particular, increase in reticulocytes proportion, in Ξ΄-aminolevulinic acid (Ξ΄-ALA) urine excretion, and the arterial hypertension’s development). Β© 2020 by the authors. Licensee MDPI, Basel, Switzerland.Funding: This work was funded by the budget of the Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers

    ΠœΠ°Ρ‚Π΅ΠΌΠ°Ρ‚ΠΈΡ‡Π΅ΡΠΊΠ°Ρ модСль ΠΎΠ΄Π½ΠΎΠΏΠΎΠ»ΡŒΠ·ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΡΠΊΠΎΠΉ ΠΊΠΎΠΌΠΏΡŒΡŽΡ‚Π΅Ρ€Π½ΠΎΠΉ ΠΈΠ³Ρ€Ρ‹, воспроизводящСй Π΄ΡƒΡΠ»ΡŒΠ½Ρ‹ΠΉ Π±ΠΎΠΉ Ρ‚Π°Π½ΠΊΠΎΠ²

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    In improving computer games, which reproduce a battle of tanks, two tasks can be distinguished: increasing a collection of game tools to represent virtual prototypes of real tank models and ensuring a realistic game. To solve these problems, a tool is necessary that allows us to compare gaming capabilities of virtual tank brands with combat capabilities of their real prototypes. A mathematical model of a computer game that reproduces a duel battle of tanks can be used as the tool. The specified model satisfies the following requirements: the sequence of operations reproduced in the model is in line with the sequence of operations implemented by the player in the course of the game; the maximum amount of ammunition that a tank can use in a model must correspond to the amount of tank ammunition. The duel lasts until one of the tanks is hit, or until all the gunshots available to hit the enemy are expended. It is necessary to find the probabilities of possible outcomes of a duel battle, the mathematical expectation of its duration, the mathematical expectation of the ammunition consumption of each side.The solution to the problem is obtained by constructing a mathematical model according to the scheme of Markov random process with discrete states and continuous time. It is implemented as a program for a model of a duel battle of tanks and can be used when developing a computer game of the genre of tank simulators to assess the gaming capabilities of the virtual tanks in a duel battle from the data on the amount of their ammunition and on the intensity of the game process transition from one state to another; for selecting the intensity values of the game process transition from one state to another, based on the data on the estimated game capabilities of virtual tanks in a duel battle. Thus, game participants can use this model to conduct their own research. Developers of computer games can use it for setting up the game and setting such intensity values of the game process transition from one state to another, at which the gaming capabilities of virtual tanks will correspond to the combat capabilities of their real prototypes on the battlefield.Π’ ΡΠΎΠ²Π΅Ρ€ΡˆΠ΅Π½ΡΡ‚Π²ΠΎΠ²Π°Π½ΠΈΠΈ ΠΊΠΎΠΌΠΏΡŒΡŽΡ‚Π΅Ρ€Π½Ρ‹Ρ… ΠΈΠ³Ρ€, воспроизводящих Π±ΠΎΠΉ Ρ‚Π°Π½ΠΊΠΎΠ², ΠΌΠΎΠΆΠ½ΠΎ Π²Ρ‹Π΄Π΅Π»ΠΈΡ‚ΡŒ Π΄Π²Π΅ Π·Π°Π΄Π°Ρ‡ΠΈ: ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠ΅ ΠΊΠΎΠ»Π»Π΅ΠΊΡ†ΠΈΠΈ ΠΈΠ³Ρ€ΠΎΠ²Ρ‹Ρ… срСдств, ΠΏΡ€Π΅Π΄ΡΡ‚Π°Π²Π»ΡΡŽΡ‰ΠΈΡ… собой Π²ΠΈΡ€Ρ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹Π΅ ΠΏΡ€ΠΎΡ‚ΠΎΡ‚ΠΈΠΏΡ‹ Ρ€Π΅Π°Π»ΡŒΠ½Ρ‹Ρ… ΠΎΠ±Ρ€Π°Π·Ρ†ΠΎΠ² Ρ‚Π°Π½ΠΊΠΎΠ²; обСспСчСнии рСалистичности ΠΈΠ³Ρ€Ρ‹. Для Ρ€Π΅ΡˆΠ΅Π½ΠΈΡ этих Π·Π°Π΄Π°Ρ‡ Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌ инструмСнт, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡŽΡ‰ΠΈΠΉ ΡΠΎΠΏΠΎΡΡ‚Π°Π²ΠΈΡ‚ΡŒ ΠΈΠ³Ρ€ΠΎΠ²Ρ‹Π΅ возмоТности Π²ΠΈΡ€Ρ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹Ρ… ΠΌΠ°Ρ€ΠΎΠΊ Ρ‚Π°Π½ΠΊΠΎΠ² с Π±ΠΎΠ΅Π²Ρ‹ΠΌΠΈ возмоТностями ΠΈΡ… Ρ€Π΅Π°Π»ΡŒΠ½Ρ‹Ρ… ΠΏΡ€ΠΎΡ‚ΠΎΡ‚ΠΈΠΏΠΎΠ², Π² качСствС ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠ³ΠΎ ΠΌΠΎΠΆΠ½ΠΎ ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΠΎΠ²Π°Ρ‚ΡŒ ΠΌΠ°Ρ‚Π΅ΠΌΠ°Ρ‚ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ модСль ΠΊΠΎΠΌΠΏΡŒΡŽΡ‚Π΅Ρ€Π½ΠΎΠΉ ΠΈΠ³Ρ€Ρ‹, Π²ΠΎΡΠΏΡ€ΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡ‰ΡƒΡŽ Π΄ΡƒΡΠ»ΡŒΠ½Ρ‹ΠΉ Π±ΠΎΠΉ Ρ‚Π°Π½ΠΊΠΎΠ². Указанная модСль удовлСтворяСт ΡΠ»Π΅Π΄ΡƒΡŽΡ‰ΠΈΠΌ трСбованиям: ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΉ, воспроизводимых Π² ΠΌΠΎΠ΄Π΅Π»ΠΈ, соотвСтствуСт ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΉ, Ρ€Π΅Π°Π»ΠΈΠ·ΡƒΠ΅ΠΌΡ‹Ρ… ΠΈΠ³Ρ€ΠΎΠΊΠΎΠΌ Π² процСссС ΠΈΠ³Ρ€Ρ‹; максимальноС количСство боСприпасов, ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠ΅ ΠΌΠΎΠΆΠ΅Ρ‚ ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΠΎΠ²Π°Ρ‚ΡŒΡΡ Ρ‚Π°Π½ΠΊΠΎΠΌ Π² ΠΌΠΎΠ΄Π΅Π»ΠΈ, Π΄ΠΎΠ»ΠΆΠ½ΠΎ ΡΠΎΠΎΡ‚Π²Π΅Ρ‚ΡΡ‚Π²ΠΎΠ²Π°Ρ‚ΡŒ Ρ€Π°Π·ΠΌΠ΅Ρ€Ρƒ Π±ΠΎΠ΅ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡ‚Π° Ρ‚Π°Π½ΠΊΠ°. Π”ΡƒΡΠ»ΡŒ продолТаСтся Π΄ΠΎ Ρ‚Π΅Ρ… ΠΏΠΎΡ€, ΠΏΠΎΠΊΠ° Π½Π΅ Π±ΡƒΠ΄Π΅Ρ‚ ΠΏΠΎΡ€Π°ΠΆΡ‘Π½ ΠΎΠ΄ΠΈΠ½ ΠΈΠ· Ρ‚Π°Π½ΠΊΠΎΠ², ΠΈΠ»ΠΈ ΠΏΠΎΠΊΠ° Π½Π΅ Π±ΡƒΠ΄ΡƒΡ‚ израсходованы всС ΠΈΠΌΠ΅ΡŽΡ‰ΠΈΠ΅ΡΡ для пораТСния ΠΏΡ€ΠΎΡ‚ΠΈΠ²Π½ΠΈΠΊΠ° ΠΏΡƒΡˆΠ΅Ρ‡Π½Ρ‹Π΅ выстрСлы. НСобходимо Π½Π°ΠΉΡ‚ΠΈ вСроятности Π²ΠΎΠ·ΠΌΠΎΠΆΠ½Ρ‹Ρ… исходов Π΄ΡƒΡΠ»ΡŒΠ½ΠΎΠ³ΠΎ боя, матСматичСскоС ΠΎΠΆΠΈΠ΄Π°Π½ΠΈΠ΅ Π΅Π³ΠΎ ΠΏΡ€ΠΎΠ΄ΠΎΠ»ΠΆΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ, матСматичСскоС ΠΎΠΆΠΈΠ΄Π°Π½ΠΈΠ΅ расхода боСприпасов ΠΊΠ°ΠΆΠ΄ΠΎΠΉ ΠΈΠ· сторон.РСшСниС Π·Π°Π΄Π°Ρ‡ΠΈ ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½ΠΎ ΠΏΡƒΡ‚Ρ‘ΠΌ построСния матСматичСской ΠΌΠΎΠ΄Π΅Π»ΠΈ ΠΏΠΎ схСмС ΠœΠ°Ρ€ΠΊΠΎΠ²ΡΠΊΠΎΠ³ΠΎ случайного процСсса с дискрСтными состояниями ΠΈ Π½Π΅ΠΏΡ€Π΅Ρ€Ρ‹Π²Π½Ρ‹ΠΌ Π²Ρ€Π΅ΠΌΠ΅Π½Π΅ΠΌ. Π Π΅Π°Π»ΠΈΠ·ΠΎΠ²Π°Π½ΠΎ Π² Π²ΠΈΠ΄Π΅ ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΡ‹ ΠΌΠΎΠ΄Π΅Π»ΠΈ Π΄ΡƒΡΠ»ΡŒΠ½ΠΎΠ³ΠΎ боя Ρ‚Π°Π½ΠΊΠΎΠ² ΠΈ ΠΌΠΎΠΆΠ΅Ρ‚ Π±Ρ‹Ρ‚ΡŒ использовано ΠΏΡ€ΠΈ Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ΅ ΠΊΠΎΠΌΠΏΡŒΡŽΡ‚Π΅Ρ€Π½ΠΎΠΉ ΠΈΠ³Ρ€Ρ‹ ΠΆΠ°Π½Ρ€Π° Ρ‚Π°Π½ΠΊΠΎΠ²Ρ‹Ρ… симуляторов для ΠΎΡ†Π΅Π½ΠΊΠΈ ΠΈΠ³Ρ€ΠΎΠ²Ρ‹Ρ… возмоТностСй Π²ΠΈΡ€Ρ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹Ρ… Ρ‚Π°Π½ΠΊΠΎΠ² Π² Π΄ΡƒΡΠ»ΡŒΠ½ΠΎΠΌ бою ΠΏΠΎ Π΄Π°Π½Π½Ρ‹ΠΌ ΠΎ Ρ€Π°Π·ΠΌΠ΅Ρ€Π°Ρ… ΠΈΡ… Π±ΠΎΠ΅ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡ‚ΠΎΠ² ΠΈ интСнсивностях ΠΏΠ΅Ρ€Π΅Ρ…ΠΎΠ΄Π° ΠΈΠ³Ρ€ΠΎΠ²ΠΎΠ³ΠΎ процСсса ΠΈΠ· ΠΎΠ΄Π½ΠΎΠ³ΠΎ состояния Π² Π΄Ρ€ΡƒΠ³ΠΎΠ΅; для ΠΏΠΎΠ΄Π±ΠΎΡ€Π° Π·Π½Π°Ρ‡Π΅Π½ΠΈΠΉ интСнсивностСй ΠΏΠ΅Ρ€Π΅Ρ…ΠΎΠ΄Π° ΠΈΠ³Ρ€ΠΎΠ²ΠΎΠ³ΠΎ процСсса ΠΈΠ· ΠΎΠ΄Π½ΠΎΠ³ΠΎ состояния Π² Π΄Ρ€ΡƒΠ³ΠΎΠ΅, исходя ΠΈΠ· Π΄Π°Π½Π½Ρ‹Ρ… ΠΎ ΠΏΡ€Π΅Π΄ΠΏΠΎΠ»Π°Π³Π°Π΅ΠΌΡ‹Ρ… ΠΈΠ³Ρ€ΠΎΠ²Ρ‹Ρ… возмоТностях Π²ΠΈΡ€Ρ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹Ρ… Ρ‚Π°Π½ΠΊΠΎΠ² Π² Π΄ΡƒΡΠ»ΡŒΠ½ΠΎΠΌ бою. Π’Π°ΠΊΠΈΠΌ ΠΎΠ±Ρ€Π°Π·ΠΎΠΌ, данная модСль ΠΌΠΎΠΆΠ΅Ρ‚ Π±Ρ‹Ρ‚ΡŒ использована участниками ΠΈΠ³Ρ€Ρ‹ для провСдСния собствСнных исслСдований; Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚Ρ‡ΠΈΠΊΠ°ΠΌΠΈ ΠΊΠΎΠΌΠΏΡŒΡŽΡ‚Π΅Ρ€Π½Ρ‹Ρ… ΠΈΠ³Ρ€, для настройки ΠΈΠ³Ρ€Ρ‹, задания Ρ‚Π°ΠΊΠΈΡ… Π·Π½Π°Ρ‡Π΅Π½ΠΈΠΉ интСнсивностСй ΠΏΠ΅Ρ€Π΅Ρ…ΠΎΠ΄Π° ΠΈΠ³Ρ€ΠΎΠ²ΠΎΠ³ΠΎ процСсса ΠΈΠ· ΠΎΠ΄Π½ΠΎΠ³ΠΎ состояния Π² Π΄Ρ€ΡƒΠ³ΠΈΠ΅, ΠΏΡ€ΠΈ ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… ΠΈΠ³Ρ€ΠΎΠ²Ρ‹Π΅ возмоТности Π²ΠΈΡ€Ρ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹Ρ… Ρ‚Π°Π½ΠΊΠΎΠ², Π±ΡƒΠ΄ΡƒΡ‚ ΡΠΎΠΎΡ‚Π²Π΅Ρ‚ΡΡ‚Π²ΠΎΠ²Π°Ρ‚ΡŒ Π±ΠΎΠ΅Π²Ρ‹ΠΌ возмоТностям ΠΈΡ… Ρ€Π΅Π°Π»ΡŒΠ½Ρ‹Ρ… ΠΏΡ€ΠΎΡ‚ΠΎΡ‚ΠΈΠΏΠΎΠ² Π½Π° ΠΏΠΎΠ»Π΅ боя

    Isolation of two strains of West Nile virus during an outbreak in southern Russia, 1999.

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    From July to September 1999, a widespread outbreak of meningoencephalitis associated with West Nile virus (Flavivirus, Flaviviridae) occurred in southern Russia, with hundreds of cases and dozens of deaths. Two strains of West Nile virus isolated from patient serum and brain-tissue samples reacted in hemagglutination-inhibition and neutralization tests with patients' convalescent-phase sera and immune ascites fluid from other strains of West Nile virus

    Impact of toxicity effects of zinc oxide nanoparticles in rats within acute and subacute experiments

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    Introduction. Occupational air is contaminated with zinc oxide nanoparticles in the copper smelting industry, especially in the smelting of brass and copper. A wide range of toxic effects with varied clinical symptomatology is observed in zinc and its compounds. Competitive relations with many other metals, including calcium, copper, and iron, are the foundation of most cases of zinc intoxication. Long-term administration of zinc or its compounds to laboratory rodents affects enzymes, carbohydrates and mineral metabolism. Materials and methods. Subchronic intoxication with repeated intraperitoneal injections and acute low respiratory tract reaction to a single intratracheal injection of zinc nanoparticles were simulated in outbred white rats. Water suspensions of zinc oxide nanoparticles with a 30-80 nm diameter were applied in both experimental models. Upon completion of the exposure, the condition of the rats in all groups was evaluated in many generally accepted criteria for toxicity. The student’s t-test was applied for statistical analysis of the obtained data. Results. Moderate intoxication development in a subchronic experiment is demonstrated. Homogeneous ultrastructural changes in the spleen tissue were revealed. Mitochondrial damage with partial or complete loss of crista is the most common. The fragmentation ratio of DNA was found by a statistically significant increase. A single intratracheal injection of zinc oxide nanoparticles revealed the increase in the attraction of cells capable of their phagocytosis (mainly neutrophils) into the low respiratory tract. This shows their cytotoxicity. Conclusion. Moderate general toxic and cytotoxic effects of zinc oxide nanoparticles on the rat body were identified. Β© 2021 Izdatel'stvo Meditsina. All rights reserved
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