What can GLAST say about the origin of cosmic rays in other galaxies ?

Gamma rays in the band from 20 MeV to 300 GeV, used in combination with data from radio and X-ray bands, provide a powerful tool for studying the origin of cosmic rays in our sister galaxies Andromeda and the Magellanic Clouds. Gamma-ray Large Area Space Telescope (GLAST) will spatially resolve these galaxies and measure the spectrum and intensity of diffuse gamma radiation from the collisions of cosmic rays with gas and dust in them. Observations of Andromeda will give an external perspective on a spiral galaxy like the Milky Way. Observations of the Magellanic Clouds will permit a study of cosmic rays in dwarf irregular galaxies, where the confinement is certainly different and the massive star formation rate is much greater.Comment: 4 pages including 6 figures; to appear in Proc. ACE-2000 Symp. "The Acceleration and Transport of Energetic Particles Observed in the Heliosphere" (Jan. 5-8, 2000, Indian Wells, CA), AIP Conf. Proc. More details can be found at the LHEA GLAST page at http://lhea-glast.gsfc.nasa.gov/pub/science/index.htm

Multi-wavelength constraints on cosmic-ray leptons in the Galaxy

Cosmic rays (CRs) interact with the gas, the radiation field and the magnetic field in the Milky Way, producing diffuse emission from radio to gamma rays. Observations of this diffuse emission and comparison with detailed predictions are powerful tools to unveil the CR properties and to study CR propagation. We present various GALPROP CR propagation scenarios based on current CR measurements. The predicted synchrotron emission is compared to radio surveys, and synchrotron temperature maps from WMAP and Planck, while the predicted interstellar gamma-ray emission is compared to Fermi-LAT observations. We show how multi-wavelength observations of the Galactic diffuse emission can be used to help constrain the CR lepton spectrum and propagation. Finally we discuss how radio and microwave data could be used in understanding the diffuse Galactic gamma-ray emission observed with Fermi-LAT, especially at low energies.Comment: 8 pages, 5 figures; in Proceedings of the 34th International Cosmic Ray Conference (ICRC 2015), The Hague (The Netherlands); Oral contributio

Fermi-LAT Observations of High- and Intermediate-Velocity Clouds: Tracing Cosmic Rays in the Halo of the Milky Way

It is widely accepted that cosmic rays (CRs) up to at least PeV energies are Galactic in origin. Accelerated particles are injected into the interstellar medium where they propagate to the farthest reaches of the Milky Way, including a surrounding halo. The composition of CRs coming to the solar system can be measured directly and has been used to infer the details of CR propagation that are extrapolated to the whole Galaxy. In contrast, indirect methods, such as observations of gamma-ray emission from CR interactions with interstellar gas, have been employed to directly probe the CR densities in distant locations throughout the Galactic plane. In this article we use 73 months of data from the Fermi Large Area Telescope in the energy range between 300 MeV and 10 GeV to search for gamma-ray emission produced by CR interactions in several high- and intermediate-velocity clouds located at up to ~ 7 kpc above the Galactic plane. We achieve the first detection of intermediate-velocity clouds in gamma rays and set upper limits on the emission from the remaining targets, thereby tracing the distribution of CR nuclei in the halo for the first time. We find that the gamma-ray emissivity per H atom decreases with increasing distance from the plane at 97.5% confidence level. This corroborates the notion that CRs at the relevant energies originate in the Galactic disk. The emissivity of the upper intermediate-velocity Arch hints at a 50% decline of CR densities within 2 kpc from the plane. We compare our results to predictions of CR propagation models.Comment: Accepted for publication in the Astrophysical Journa

The Origin of Cosmic Rays and the Diffuse Galactic Gamma-Ray Emission

Cosmic-ray interactions with interstellar gas and photons produce diffuse gamma-ray emission. In this talk we will review the current understanding of this diffuse emission and its relationship to the problem of the origin of cosmic rays. We will discuss the open issues and what progress might be possible with GLAST, which is planned for launch in 2006.Comment: 10 pages, 5 figures. Invited talk at the "Gamma 2001" Symp., April 4-6, 2001, Baltimore, MD. AIP Conf. Proc. v.587, eds. S. Ritz, N. Gehrels, & C. R. Shrader, in pres

Physicochemical and Antibacterial Properties of Composite Films Based on Bacterial Cellulose and Chitosan for Wound Dressing Materials

New bacterial cellulose/chitosan (BC/Ch) nanocomposite films were obtained using a simple procedure by immersing BC synthesized by Komagataeibacter xylinus in 1% acetic acid solutions of Ch with the degree of deacetylation 75‒85% of medium molecular weight. The BC and BC/Ch composites chemical composition was examined by FTIR, the mechanical properties by a tensile tester, surface morphology by scanning electron microscopy, and antibacterial activity against S. aureus, E. coli and P. aeruginosa by diffusion and joint incubation methods. The FTIR spectra indicated the intermolecular interaction between BC and Ch. Due to addition of 0.6% (w/v) Ch, the films of BC/Ch become more homogeneous with a significantly denser fibril structure, smaller pore diameter and higher surface area in comparison to those of pure BC films. Micro- (15‒35 nm) and macrofibrils (50‒150 nm) in both BC and BC/Ch films are joined in ribbon-like fibers, providing a high degree of mechanical strength (Young’s modulus: 33‒36 MPa, tensile strength and elongation et break: 17, 22 MPa). The obtained hybrid material is transparent, flexible and displays good water absorption capacity and water vapor permeability. The films have reasonable thermal stability to be in contact with body or during steam sterilization, since maximum degradation temperature (Td) of both biocomposites is around 400‒600 °C. The disc diffusion method confirmed that the BC/Ch films have predominantly non-diffusible antibacterial properties. Antibacterial assessment by the joint incubation method proved that addition of Ch to BC films resulted in significant growth inhibition against target bacteria. The BC/Ch biocomposites’ notable properties make them suitable for wound healing applications

The distribution of cosmic-ray sources in the Galaxy, gamma-rays, and the gradient in the CO-to-H2 relation

We present a solution to the apparent discrepancy between the radial gradient in the diffuse Galactic gamma-ray emissivity and the distribution of supernova remnants, believed to be the sources of cosmic rays. Recent determinations of the pulsar distribution have made the discrepancy even more apparent. The problem is shown to be plausibly solved by a variation in the CO-to-N(H2) scaling factor. If this factor increases by a factor of 5-10 from the inner to the outer Galaxy, as expected from the Galactic metallicity gradient, we show that the source distribution required to match the radial gradient of gamma-ray can be reconciled with the distribution of supernova remnants as traced by current studies of pulsars. The resulting model fits the EGRET gamma-ray profiles extremely well in longitude, and reproduces the mid-latitude inner Galaxy intensities better than previous models.Comment: Accepted for publication in Astronomy & Astrophysics Letter

From powder to solution: hydration dependence of human hemoglobin dynamics correlated to body temperature

A transition in hemoglobin (Hb), involving partial unfolding and aggregation, has been shown previously by various biophysical methods. The correlation between the transition temperature and body temperature for Hb from different species, suggested that it might be significant for biological function. In order to focus on such biologically relevant human Hb dynamics, we studied the protein internal picosecond motions as a response to hydration, by elastic and quasielastic neutron scattering. Rates of fast diffusive motions were found to be significantly enhanced with increasing hydration from fully hydrated powder to concentrated Hb solution. In concentrated protein solution, the data revealed that amino acid side-chains can explore larger volumes above body temperature than expected from normal temperature dependence. The body temperature transition in protein dynamics was absent in fully hydrated powder, indicating that picosecond protein dynamics responsible for the transition is activated only at a sufficient level of hydration. A collateral result from the study is that fully hydrated protein powder samples do not accurately describe all aspects of protein picosecond dynamics that might be necessary for biological function