88 research outputs found
Integrability of a conducting elastic rod in a magnetic field
We consider the equilibrium equations for a conducting elastic rod placed in
a uniform magnetic field, motivated by the problem of electrodynamic space
tethers. When expressed in body coordinates the equations are found to sit in a
hierarchy of non-canonical Hamiltonian systems involving an increasing number
of vector fields. These systems, which include the classical Euler and
Kirchhoff rods, are shown to be completely integrable in the case of a
transversely isotropic rod; they are in fact generated by a Lax pair. For the
magnetic rod this gives a physical interpretation to a previously proposed
abstract nine-dimensional integrable system. We use the conserved quantities to
reduce the equations to a four-dimensional canonical Hamiltonian system,
allowing the geometry of the phase space to be investigated through Poincar\'e
sections. In the special case where the force in the rod is aligned with the
magnetic field the system turns out to be superintegrable, meaning that the
phase space breaks down completely into periodic orbits, corresponding to
straight twisted rods.Comment: 19 pages, 1 figur
3 year report on activities for the Working Group on Phytoplankton and Microbial Ecology (WGPME)
The ICES Working Group on Phytoplankton and Microbial Ecology (WGPME) provides tools
and expert perspectives on the sampling methods, ecology and diversity of phytoplankton and
other planktonic microbes. The group set out terms of reference to improve access to data, crossdisciplinary approaches and to develop ecological interpretations of the changing phytoplankton seascape. The group published 16 papers between 2019–2021, including key tools, high-profile synthesis papers and science reports.
Tools: The group has progressed efforts to collect images of commonly used Lugol’s-preserved
phytoplankton, alongside live images to aid those in correctly identifying species. Members have
noticed and published records of new phytoplankton species. The group aims to produce a New
Records database to assist in notifying new or reoccurrence of a species. WGPME work, with
other Expert Groups (EG) to improve access to molecular genetic tools and records. A multi-EG
thematic session has been submitted for ICES ASC 2022 in cooperation with other EGs, whilst
phytoplankton barcoding information will be incorporated into the Working Group on Integrated Morphological and Molecular Taxonomy (WGIMT) barcoding Atlas (https://metazoogene.org/atlas).
Information and access: The group is gathering information on nano and picoplankton (small
phytoplankton less than 10 and 2µm respectively) to incorporate into global datasets such as
GLOMICON. Multiple data sources point to an increasing trend in picoplankton and few indicators exist in current EU or national legislation to measure their impact on marine ecology.
Many members are involved in indicator development for governmental and pan-governmental
organisations such as OSPAR. However, the number and level of indicators vary in each country.
Long-term ecology: The cooperative zooplankton and phytoplankton report has been delayed
but initial analysis has indicated ≥30 years of data reliably shows spatio-temporal trends in phytoplankton and the effects of temperature on key phytoplankton groups. Two research papers
are being produced on climate change effects on key marine phytoplankton species with the
additional aim of improving indicators of change using species-specific information
Biology Teachers Designing Context-Based Lessons for Their Classroom Practice—The importance of rules-of-thumb
Cannabinoid type 1 receptor mediates depot-specific effects on differentiation, inflammation and oxidative metabolism in inguinal and epididymal white adipocytes
Epidemiology of intra-abdominal infection and sepsis in critically ill patients: “AbSeS”, a multinational observational cohort study and ESICM Trials Group Project
Purpose: To describe the epidemiology of intra-abdominal infection in an international cohort of ICU patients according to a new system that classifies cases according to setting of infection acquisition (community-acquired, early onset hospital-acquired, and late-onset hospital-acquired), anatomical disruption (absent or present with localized or diffuse peritonitis), and severity of disease expression (infection, sepsis, and septic shock). Methods: We performed a multicenter (n = 309), observational, epidemiological study including adult ICU patients diagnosed with intra-abdominal infection. Risk factors for mortality were assessed by logistic regression analysis. Results: The cohort included 2621 patients. Setting of infection acquisition was community-acquired in 31.6%, early onset hospital-acquired in 25%, and late-onset hospital-acquired in 43.4% of patients. Overall prevalence of antimicrobial resistance was 26.3% and difficult-to-treat resistant Gram-negative bacteria 4.3%, with great variation according to geographic region. No difference in prevalence of antimicrobial resistance was observed according to setting of infection acquisition. Overall mortality was 29.1%. Independent risk factors for mortality included late-onset hospital-acquired infection, diffuse peritonitis, sepsis, septic shock, older age, malnutrition, liver failure, congestive heart failure, antimicrobial resistance (either methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, extended-spectrum beta-lactamase-producing Gram-negative bacteria, or carbapenem-resistant Gram-negative bacteria) and source control failure evidenced by either the need for surgical revision or persistent inflammation. Conclusion: This multinational, heterogeneous cohort of ICU patients with intra-abdominal infection revealed that setting of infection acquisition, anatomical disruption, and severity of disease expression are disease-specific phenotypic characteristics associated with outcome, irrespective of the type of infection. Antimicrobial resistance is equally common in community-acquired as in hospital-acquired infection
Value of risk scores in the decision to palliate patients with ruptured abdominal aortic aneurysm
Background: The aim of this study was to develop a 48-h mortality risk score, which included morphology data, for patients with ruptured abdominal aortic aneurysm presenting to an emergency department, and to assess its predictive accuracy and clinical effectiveness in triaging patients to immediate aneurysm repair, transfer or palliative care. Methods: Data from patients in the IMPROVE (Immediate Management of the Patient With Ruptured Aneurysm: Open Versus Endovascular Repair) randomized trial were used to develop the risk score. Variables considered included age, sex, haemodynamic markers and aortic morphology. Backwards selection was used to identify relevant predictors. Predictive performance was assessed using calibration plots and the C-statistic. Validation of the newly developed and other previously published scores was conducted in four external populations. The net benefit of treating patients based on a risk threshold compared with treating none was quantified. Results: Data from 536 patients in the IMPROVE trial were included. The final variables retained were age, sex, haemoglobin level, serum creatinine level, systolic BP, aortic neck length and angle, and acute myocardial ischaemia. The discrimination of the score for 48-h mortality in the IMPROVE data was reasonable (C-statistic 0·710, 95 per cent c.i. 0·659 to 0·760), but varied in external populations (from 0·652 to 0·761). The new score outperformed other published risk scores in some, but not all, populations. An 8 (95 per cent c.i. 5 to 11) per cent improvement in the C-statistic was estimated compared with using age alone. Conclusion: The assessed risk scores did not have sufficient accuracy to enable potentially life-saving decisions to be made regarding intervention. Focus should therefore shift to offering repair to more patients and reducing non-intervention rates, while respecting the wishes of the patient and family
A neuronal activation correlate in striatum and prefrontal cortex of prolonged cocaine intake
- …