Dynamics of magnetization on the topological surface

We investigate theoretically the dynamics of magnetization coupled to the surface Dirac fermions of a three dimensional topological insulator, by deriving the Landau-Lifshitz-Gilbert (LLG) equation in the presence of charge current. Both the inverse spin-Galvanic effect and the Gilbert damping coefficient $\alpha$ are related to the two-dimensional diagonal conductivity $\sigma_{xx}$ of the Dirac fermion, while the Berry phase of the ferromagnetic moment to the Hall conductivity $\sigma_{xy}$. The spin transfer torque and the so-called $\beta$-terms are shown to be negligibly small. Anomalous behaviors in various phenomena including the ferromagnetic resonance are predicted in terms of this LLG equation.Comment: 4+ pages, 1 figur

Interchain Coupling Effects and Solitons in CuGeO_3

The effects of interchain coupling on solitons and soliton lattice structures in CuGeO3 are explored. It is shown that interchain coupling substantially increases the soliton width and changes the soliton lattice structures in the incommensurate phase. It is proposed that the experimentally observed large soliton width in CuGeO3 is mainly due to interchain coupling effects.Comment: 4 pages, LaTex, one eps figure included. No essential changes except forma

High power photon collimators for the ILC.

An undulator-based source has been chosen as a part of the baseline configuration for the International Linear Collider (ILC) to generate an intense beam of polarised positrons. A photon collimator placed between the undulator and the target can be used to adjust the size, intensity and polarisation of the photon beam impacting the target, and can also protect the target station and limit the activation of downstream components. In this paper, we calculate quantities such as the energy deposition, temperature change, activation and dose rate for different designs of the photon collimator, and consider the advantages and disadvantages for each case

On the soliton width in the incommensurate phase of spin-Peierls systems

We study using bosonization techniques the effects of frustration due to competing interactions and of the interchain elastic couplings on the soliton width and soliton structure in spin-Peierls systems. We compare the predictions of this study with numerical results obtained by exact diagonalization of finite chains. We conclude that frustration produces in general a reduction of the soliton width while the interchain elastic coupling increases it. We discuss these results in connection with recent measurements of the soliton width in the incommensurate phase of CuGeO_3.Comment: 4 pages, latex, 2 figures embedded in the tex

Mode Shape Description and Model Updating of Axisymmetric Structures Using Radial Tchebichef Moment Descriptors

A novel approach for mode shape feature extraction and model updating of axisymmetric structures based on radial Tchebichef moment (RTM) descriptors is proposed in this study. The mode shape features extracted by RTM descriptors can effectively compress the full-field modal vibration data and retain the most important information. The reconstruction of mode shapes using RTM descriptors can accurately describe the mode shapes, and the simulation shows that the RTM function is superior to Zernike moment function in terms of its mathematical properties and its shape reconstruction ability. In addition, the proposed modal correlation coefficient of the RTM amplitude can overcome the main disadvantage of using the modal assurance criterion (MAC), which has difficulty in identifying double or close modes of symmetric structures. Furthermore, the model updating of axisymmetric structures based on RTM descriptors appears to be more efficient and effective than the normal model updating method directly using modal vibration data, avoids manipulating large amounts of mode shape data, and speeds up the convergence of updating parameters. The RTM descriptors used in correlation analysis and model updating are demonstrated with a cover of an aeroengine rig. The frequency deviation between the test and the FE model was reduced from 17.13% to 1.23% for the first 13 modes via the model updating process. It verified the potential to industrial application with the proposed method

Cell-Based Assays in High-Throughput Screening for Drug Discovery

Drug screening is a long and costly process confronted with low productivity and challenges in using animals, which limit the discovery of new drugs.  To improve drug screening efficacy and minimize animal testing, recent efforts have been dedicated to developing cell-based high throughput screening (HTS) platforms that can provide more relevant in vivo biological information than biochemical assays and thus reduce the number of animal tests and accelerate the drug discovery process. Today, cell-based assays are used in more than half of all high-throughput drug screenings for target validation and ADMET (absorption, distribution, metabolism, elimination and toxicity) in the early stage of drug discovery. In this review, we discuss the uses of different types of cells and cell culture systems, including 2D, 3D and perfusion cell cultures, in cell-based HTS for drug discovery. Optical and electrochemical methods for online, non-invasive detection and quantification of cells or cellular activities are discussed. Recent progresses and applications of 3D cultures and microfluidic systems for cell-based HTS are also discussed, followed with several successful examples of using cell-based HTS in commercial development of new drugs. Finally, a brief discussion on potential applications of cell-based HTS for screening phytochemicals and herbal medicines is provided in this review

Low-Temperature Spin Dynamics of Doped Manganites: roles of Mn-t2g and eg and O-2p states

The low-temperature spin dynamics of doped manganites have been analyzed within a tight-binding model, the parameters of which are estimated by mapping the results of ab initio density functional calculations onto the model. This approach is found to provide a good description of the spin dynamics of the doped manganites, observed earlier within the ab initio calculations. Our analysis not only provides some insight into the roles of the eg and the t2g states but also indicates that the oxygen p states play an important role in the spin dynamics. This may cast doubt on the adaptability of the conventional model Hamiltonian approaches to the analysis of spin dynamics of doped manganites.Comment: 12 pages; Includes 5 figure