Design and Simulation of Wind Pump System for Ban Village

The significance of water to human existence can never be overemphasized. Most rural areas do not have access to portable drinking water. Underground water has been adjudged by World Health Organization (WHO) to be a relatively better alternative source of portable drinking water. Hand pump may not provide adequate water for larger community; diesel engine pump emits Green House Gases (GHG). Thus a relatively better alternative source of energy is the wind. Wind pump is designed for Ban village to pump water from borehole to an overhead tank to be supplied to the village, since Ban village is considered to be one of the locations in Nigeria that has high wind speed that can be harnessed for wind pump technology. Design results show that a 3.6 m diameter wind mill will be required to pump water from borehole through a total head of 35 m to the village to meet the daily water need of 25 m3. Results from the Wind Energy Resources Analysis (WERA) software simulation using the wind speed characteristics of the region shows that the monthly water discharge by wind pump is proportional to the monthly average wind speed with the peak monthly discharge of about 3000 m3 in January which declines to about 1,000 m3 in October. This volume of water is enough to meet the monthly water need of the village. Keywords: Wind speed, Wind pump, Simulation

Energy Exploitation And Environmental Impact In Nigeria: The Way Forward.

Energy is the basis of industrial civilisation; without energy, modern life would be difficult to live. However, the exploitation and utilisation of energy in this case non-renewable energy (oil, gas and coal) comes with effects that impact negatively on the environment such as environmental pollution which affects weather conditions, soil fertility, aquatic habitats and wildlife animals. This paper, after highlighting the various environmental impact of energy exploitation, emphasizes on the need for the stakeholders, in this context, government, engineers, scientist, investors and community leaders to rise up to the challenges and ensure that the impacts of energy to the environment are addressed. It advocates for interdisciplinary approach and strict adherence to professional ethics by engineers and scientists to address the problems while the appropriate government agencies should enforce the various environmental laws. And judging by the threat the non-renewable energy exploitation poses to humans and the environment, the paper suggests a gradual shift to clean energy technology for sustainable development.Key words: Energy Exploitation, Environment Pollution, Modern Technologies, Sustainable Development

Immobilization of Polymer-Decorated Liquid Crystal Droplets on Chemically Tailored Surfaces

We demonstrate that the assembly of an amphiphilic polyamine on the interfaces of micrometer-sized droplets of a thermotropic liquid crystal (LC) dispersed in aqueous solutions can be used to facilitate the immobilization of LC droplets on chemically functionalized surfaces. Polymer 1 was designed to contain both hydrophobic (alkylfunctionalized) and hydrophilic (primary and tertiary amine-functionalized) side chain functionality. The assembly of this polymer at the interfaces of aqueous dispersions of LC droplets was achieved by the spontaneous adsorption of polymer from aqueous solution. Polymer adsorption triggered transitions in the orientational ordering of the LCs, as observed by polarized light and bright-field microscopy. We demonstrate that the presence of polymer 1 on the interfaces of these droplets can be exploited to immobilize LC droplets on planar solid surfaces through covalent bond formation (e.g., for surfaces coated with polymer multilayers containing reactive azlactone functionality) or through electrostatic interactions (e.g., for surfaces coated with multilayers containing hydrolyzed azlactone functionality). The characterization of immobilized LC droplets by polarized, fluorescence, and laser scanning confocal microscopy revealed the general spherical shape of the polymer-coated LC droplets to be maintained after immobilization, and that immobilization led to additional ordering transitions within the droplets that were dependent on the nature of the surfaces with which they were in contact. Polymer 1-functionalized LC droplets were not immobilized on polymer multilayers treated with poly(ethylene imine) (PEI). We demonstrate that the ability to design surfaces that promote or prevent the immobilization of polymer-functionalized LC droplets can be exploited to pattern the immobilization of LC droplets on surfaces. The results of this investigation provide the basis of an approach that could be used to tailor the properties of dispersed LC emulsions and to immobilize these droplets on functional surfaces of interest in a broad range of fundamental and applied contexts

Integrating Indigenous Knowledge with Scientific Seasonal Forecasts for Climate Risk Management in Lushoto District in Tanzania

Improving food security needs appropriate climate related risk management strategies. These include using climate information to guide farm level decision-making. Progress has been made in providing climate services in Tanzania but there are significant gaps with regard to downscaled location specific forecasts, as well as generating timely, reliable and user friendly information. Majority of the farmers have been using indigenous knowledge (IK) forecasts to predict weather through observing the behavior of large animals, birds, plants, insects, and the solar system. IK is not often documented and is mainly sustained from one generation to another through oral history and local expertise, creating a wide inter-generational gap between its custodians and the young people. This study identifies and documents existing IK in weather forecasting in Lushoto district, northern Tanzania, and aims at promoting the integration of IK and scientific weather forecasting for climate risk management. Historical rainfall data was used in combination with data collected through household surveys, focus group discussions and key informant interviews. Majority of the farmers (56%) indicated that weather forecasts using IK were more reliable and specific to their location compared to scientific forecasts. Comparison was made of the seasonal March-April-May (MAM) forecasts in 2012 from IK and Tanzania Meteorological Agency (TMA), with both approaches predicting a normal rainy season. The IK forecasts were, however, more reliable in the long rainy MAM season compared to the short rainy October-November- December season. To improve accuracy, systematic documentation of IK and establishment of a framework for integrating IK and TMA weather forecasting is needed. There is also a need to establish an information dissemination network and entrench weather forecasting within the District Agricultural Development Programmes

TGF-β-induced growth inhibition in B-cell lymphoma correlates with Smad1/5 signalling and constitutively active p38 MAPK

<p>Abstract</p> <p>Background</p> <p>Cytokines of the transforming growth factor β (TGF-β) superfamily exert effects on proliferation, apoptosis and differentiation in various cell types. Cancer cells frequently acquire resistance to the anti-proliferative signals of TGF-β, which can be due to mutations in proteins of the signalling cascade. We compared the TGF-β-related signalling properties in B-cell lymphoma cell lines that were sensitive or resistant to TGF-β-induced anti-proliferative effects.</p> <p>Results</p> <p>TGF-β sensitive cell lines expressed higher cell surface levels of the activin receptor-like kinase 5 (Alk-5), a TGF-β receptor type 1. The expression levels of the other TGF-β and bone morphogenetic protein receptors were comparable in the different cell lines. TGF-β-induced phosphorylation of Smad2 was similar in TGF-β sensitive and resistant cell lines. In contrast, activation of Smad1/5 was restricted to cells that were sensitive to growth inhibition by TGF-β. Moreover, with activin A we detected limited anti-proliferative effects, strong phosphorylation of Smad2, but no Smad1/5 phosphorylation. Up-regulation of the TGF-β target genes Id1 and Pai-1 was identified in the TGF-β sensitive cell lines. Constitutive phosphorylation of MAPK p38 was restricted to the TGF-β sensitive cell lines. Inhibition of p38 MAPK led to reduced sensitivity to TGF-β.</p> <p>Conclusions</p> <p>We suggest that phosphorylation of Smad1/5 is important for the anti-proliferative effects of TGF-β in B-cell lymphoma. Alk-5 was highly expressed in the sensitive cell lines, and might be important for signalling through Smad1/5. Our results indicate a role for p38 MAPK in the regulation of TGF-β-induced anti-proliferative effects.</p

Dynamic Ordering Transitions of Liquid Crystals Driven by Interfacial Complexes Formed Between Polyanions and Amphiphilic Polyamines

We report the design of an amphiphilic polyamine (polymer 1) based on poly(2-alkenyl azlactone) that strongly couples the formation of polyelectrolyte complexes at aqueous/liquid crystal (LC) interfaces to ordering transitions in the LC. We demonstrate that the addition of a strong anionic polyelectrolyte to aqueous solutions in contact with polymer 1-laden LC interfaces (prepared by Langmuir-Schaefer transfer of monolayers of polymer 1 onto micrometerthick films of nematic LC) triggers ordering transitions in the LCs. We further demonstrate that changes in the ordering of the LCs (i) are driven by electrostatic interactions between the polyelectrolytes, (ii) involve multivalent interactions between the polyelectrolytes, and (iii) are triggered by reorganization of the hydrophobic side chains of amphiphilic polymer 1 upon formation of the interfacial complexes. The results presented in this paper lead us to conclude that ordering transitions in LCs can be used to provide insights into the structure and dynamics of interfacial complexes formed between polyelectrolytes

The ACS survey of globular clusters. XIII. Photometric calibration in comparison with Stetson standards

In this study we compare the photometric data of 34 Milky Way globular clusters, observed within the ACS Treasury Program (PI: Ata Sarajedini) with the corresponding ground-based data, provided by the Photometric Standard Field Catalogs of Stetson (2000, 2005). We focus on the transformation between the HST/ACS F606W to V-band and F814W to I-band only. The goal is to assess the validity of the filter transformation equations by Sirianni et al.(2005) with respect to their dependence on metallicity, Horizontal Branch morphology, mass and integrated (V-I) colour of the various globular clusters. Such a dependence is expected due to the fact that the transformation equations are based on the observations of only one globular cluster, i.e., NGC 2419. Surprisingly, the correlation between offset and metallicity is found to be weak, with a low level significance. The correlation between offset and Horizontal Branch structure, as well as total cluster mass is still weaker. Based on the available data we do not find the photometric offset to be linked to multiple stellar populations, e.g., as found in NGC 0288, NGC 1851, and NGC 5139. The results of this study show that there are small systematic offsets between the transformed ACS- and observed ground based photometry, and that these are only weakly correlated, if at all, with various cluster parameters and their underlying stellar populations. As a result, investigators wishing to transform globular cluster photometry from the Sirianni et al.(2005) ground-based V, I system onto the Stetson (2000) system simply need to add 0.040 (+/-0.012) to the V-band magnitudes and 0.047 (+/-0.011) to the I-band magnitudes. This in turn means that the transformed ACS (V-I) colours match the ground-based values from Stetson (2000) to within ~0.01 mag.Comment: 28 pages, 14 figures, accepted for publication in ApJ

Directed Design of a AuI Complex with a Reduced Mesoionic Carbene Radical Ligand: Insights from 1,2,3‐Triazolylidene Selenium Adducts and Extensive Electrochemical Investigations

Carbene-based radicals are important for both fundamental and applied chemical research. Herein, extensive electrochemical investigations of nine different 1,2,3-triazolylidene selenium adducts are reported. It is found that the half-wave potentials of the first reduction of the selones correlate with their calculated LUMO levels and the LUMO levels of the corresponding triazolylidene-based mesoionic carbenes (MICs). Furthermore, unexpected quasi-reversibility of the reduction of two triazoline selones, exhibiting comparable reduction potentials, was discovered. Through UV/Vis/NIR and EPR spectroelectrochemical investigations supported by DFT calculations, the radical anion was unambiguously assigned to be triazoline centered. This electrochemical behavior was transferred to a triazolylidene-type MIC-gold phenyl complex resulting in a MIC-radical coordinated Au-I species. Apart from UV-Vis-NIR and EPR spectroelectrochemical investigations of the reduction, the reduced gold-coordinated MIC radical complex was also formed in situ in the bulk through chemical reduction. This is the first report of a monodentate triazolylidene-based MIC ligand that can be reduced to its anion radical in a metal complex. The results presented here provide design principles for stabilizing radicals based on MICs

Langmuir Films of Flexible Polymers Transferred to Aqueous/Liquid Crystal Interfaces Induce Uniform Azimuthal Alignment of the Liquid Crystal

We reported recently that amphiphilic polymers can be assembled at interfaces created between aqueous phases and thermotropic liquid crystals (LCs) in ways that: (i) couple the organization of the polymer to the order of the LC and (ii) respond to changes in the properties of aqueous phases that can be characterized as changes in the optical appearance of the LC. This investigation sought to characterize the behavior of aqueous-LC interfaces decorated with uniaxially compressed thin films of polymers transferred by Langmuir-Schaefer (LS) transfer. Here, we report physicochemical characterization of interfaces created between aqueous phases and the thermotropic LC 4-cyano-4′-pentylbiphenyl (5CB) decorated with Langmuir films of a novel amphiphilic polymer (polymer 1), synthesized by the addition of hydrophobic and hydrophilic side chains to poly(2-vinyl-4,4′-dimethylazlactone). Initial characterization of this system resulted in the unexpected observation of uniform azimuthal alignment of 5CB after LS transfer of the polymer films to aqueous-5CB interfaces. This paper describes characterization of Langmuir films of polymer 1 hosted at aqueous-5CB interfaces as well as the results of our investigations into the origins of the uniform ordering of the LC observed upon LS transfer. Our results, when combined, support the conclusion that uniform azimuthal alignment of 5CB is the result of long-range ordering of polymer chains in the Langmuir films (in a preferred direction orthogonal to the direction of compression) that is generated during uniaxial compression of the films prior to LS transfer. Although past studies of Langmuir films of polymers at aqueous-air interfaces have demonstrated that in-plane alignment of polymer backbones can be induced by uniaxial compression, these past reports have generally made use of polymers with rigid backbones. One important outcome of this current study is thus the observation of anisotropy and long-range order in Langmuir films of a novel flexible polymer. A second important outcome is the observation that the existence, extent, and dynamics of this order can be identified and characterized optically by transfer of the Langmuir film to a thin film of LC. Additional characterization of Langmuir films of two other flexible polymers [poly(methyl methacrylate) and poly(vinyl stearate)] using this method also resulted in uniform azimuthal alignment of 5CB, suggesting that the generation of long-range order in uniaxially compressed Langmuir films of polymers may also occur more generally over a broader range of polymers with flexible backbones