266 research outputs found
Indium Arsenide Solid Solutions: Devices Based on InGaAs(P)
This paper is a review of literature and data dealing with the properties of indium arsenide-based solid solutions and several devices on InGaAs(P)/ZnP heterostructures. Possible practical applications of the 111 V-II12VI,heterostructures are indicated.The most interesting results obtained in the fabrication of high quality heterostructures, including modulation-doped and quantum-dimensional ones are demonstrated. The epitaxial methods bsed for the production of heterostructures are comparatively analised. Data about applicability ofepitaxial methodsfor fabrication ofdifferent device structures are reported.An interesting 'cleaning' effect taking place at the InGaAs(P) crystallization by LPE from solutions containing rare-earth elements is described.A review of recently published works on fabrication of effective FET ismade. The HEMT technology thought to be the most promising one, issupposed to contribute to a qualitatively new development stage of large integral circuits on A3B5, while a combination of HEMT with thetechnology of quantum-dimensional lasers is expected to accelerate thecreation of high speed response integral circuits
ΠΠΈΡΠΊΡΡΡΠΈΠ²Π½ΠΎ-ΠΏΡΠ°Π³ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ·ΡΠΊΠΎΠ²ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·Π°
The paper considers the problems of language modeling of the image of the world, allowing to recreate the basic concepts, topics of reality they represent. A special place is occupied among them by the modeling of the subjective image of a charismatic personality, which in one way or another personifies the life-sense of his era (Peter I, mother Theresa, Iron Lady, Theresa May, etc.). The focus is on the spiritual, physical and ideological modi of the created language image, its suggestive interaction and the development of society. The peculiarity of the linguistic image is that the person is synergistically recreated, he is not outside of the subjective attitude of the author of the text, whether it is mass media or artistic and historical texts. Though subjective, the linguistic image is created through the speech interpretation of realities. The linguistic image embodies the real world with the help of semantic dynamics of words, representing ideologemes, culturemes and concepts as cognitive-discursive constructs of a socially significant event.El artΓculo considera los problemas del modelado del lenguaje de la imagen del mundo, permitiendo recrear los conceptos bΓ‘sicos, temas de la realidad que representan. Un lugar especial estΓ‘ ocupado entre ellos por el modelado de la imagen subjetiva de una personalidad carismΓ‘tica, que de una u otra manera personifica el sentido de la vida de su Γ©poca (Pedro I, madre Teresa, Hierro Dama, Teresa Mayo, etc.). La atenciΓ³n se centra en el modo espiritual, fΓsico e ideolΓ³gico de la imagen del lenguaje creado, su interacciΓ³n sugerente y el desarrollo de la sociedad. La peculiaridad de la imagen lingΓΌΓstica es que la persona se recrea de forma sinΓ©rgica, no estΓ‘ fuera de la actitud subjetiva del autor del texto, ya sea en los medios de comunicaciΓ³n o en los textos artΓsticos e histΓ³ricos. Aunque subjetiva, la imagen lingΓΌΓstica se crea a travΓ©s de la interpretaciΓ³n del habla de las realidades. La imagen lingΓΌΓstica encarna el mundo real con la ayuda de dinΓ‘micas semΓ‘nticas de palabras, representando ideologΓas, culturemas y conceptos como construcciones cognitivas-discursivas de un evento socialmente significativo.Π ΡΡΠ°ΡΡΠ΅ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°ΡΡΡΡ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ ΡΠ·ΡΠΊΠΎΠ²ΠΎΠ³ΠΎ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΎΠ±ΡΠ°Π·Π° ΠΌΠΈΡΠ°, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡΠΈΠ΅ Π²ΠΎΡΡΠΎΠ·Π΄Π°ΡΡ ΠΎΡΠ½ΠΎΠ²Π½ΡΠ΅ ΠΏΠΎΠ½ΡΡΠΈΡ, ΡΠ΅ΠΌΡ ΡΠ΅Π°Π»ΡΠ½ΠΎΡΡΠΈ, ΠΊΠΎΡΠΎΡΡΠ΅ ΠΎΠ½ΠΈ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΡΡ. ΠΡΠΎΠ±ΠΎΠ΅ ΠΌΠ΅ΡΡΠΎ ΡΡΠ΅Π΄ΠΈ Π½ΠΈΡ
Π·Π°Π½ΠΈΠΌΠ°Π΅Ρ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΡΠ±ΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·Π° Ρ
Π°ΡΠΈΠ·ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π»ΠΈΡΠ½ΠΎΡΡΠΈ, ΠΊΠΎΡΠΎΡΠ°Ρ ΡΠ°ΠΊ ΠΈΠ»ΠΈ ΠΈΠ½Π°ΡΠ΅ ΠΎΠ»ΠΈΡΠ΅ΡΠ²ΠΎΡΡΠ΅Ρ ΠΆΠΈΠ·Π½Π΅Π½Π½ΡΠΉ ΡΠΌΡΡΠ» Π΅Π³ΠΎ ΡΠΏΠΎΡ
ΠΈ (ΠΠ΅ΡΡ I, ΠΌΠ°ΡΡ Π’Π΅ΡΠ΅Π·Π°, ΠΠ΅Π»Π΅Π·Π½Π°Ρ Π»Π΅Π΄ΠΈ, Π’Π΅ΡΠ΅Π·Π° ΠΡΠΉ ΠΈ Π΄Ρ.). ΠΡΠ½ΠΎΠ²Π½ΠΎΠ΅ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ ΡΠ΄Π΅Π»ΡΠ΅ΡΡΡ Π΄ΡΡ
ΠΎΠ²Π½ΡΠΌ, ΡΠΈΠ·ΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΈ ΠΈΠ΄Π΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΌ ΡΠΏΠΎΡΠΎΠ±Π°ΠΌ ΡΠΎΠ·Π΄Π°Π²Π°Π΅ΠΌΠΎΠ³ΠΎ ΡΠ·ΡΠΊΠΎΠ²ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·Π°, Π΅Π³ΠΎ Π²Π½ΡΡΠ°ΡΡΠ΅ΠΌΡ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ ΠΈ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΎΠ±ΡΠ΅ΡΡΠ²Π°. ΠΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΡ ΡΠ·ΡΠΊΠΎΠ²ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·Π° Π·Π°ΠΊΠ»ΡΡΠ°Π΅ΡΡΡ Π² ΡΠΎΠΌ, ΡΡΠΎ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊ ΡΠΈΠ½Π΅ΡΠ³Π΅ΡΠΈΡΠ΅ΡΠΊΠΈ Π²ΠΎΡΡΠΎΠ·Π΄Π°Π½, ΠΎΠ½ Π½Π΅ Π½Π°Ρ
ΠΎΠ΄ΠΈΡΡΡ Π²Π½Π΅ ΡΡΠ±ΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΡ Π°Π²ΡΠΎΡΠ° ΡΠ΅ΠΊΡΡΠ°, Π±ΡΠ΄Ρ ΡΠΎ ΡΡΠ΅Π΄ΡΡΠ²Π° ΠΌΠ°ΡΡΠΎΠ²ΠΎΠΉ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΈ ΠΈΠ»ΠΈ Ρ
ΡΠ΄ΠΎΠΆΠ΅ΡΡΠ²Π΅Π½Π½ΠΎ-ΠΈΡΡΠΎΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ΅ΠΊΡΡΡ. ΠΠΈΠ½Π³Π²ΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΠΎΠ±ΡΠ°Π·, Ρ
ΠΎΡΡ ΠΈ ΡΡΠ±ΡΠ΅ΠΊΡΠΈΠ²Π½ΡΠΉ, ΡΠΎΠ·Π΄Π°Π΅ΡΡΡ ΠΏΠΎΡΡΠ΅Π΄ΡΡΠ²ΠΎΠΌ ΡΠ΅ΡΠ΅Π²ΠΎΠΉ ΠΈΠ½ΡΠ΅ΡΠΏΡΠ΅ΡΠ°ΡΠΈΠΈ ΡΠ΅Π°Π»ΠΈΠΉ. ΠΠΈΠ½Π³Π²ΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΠΎΠ±ΡΠ°Π· Π²ΠΎΠΏΠ»ΠΎΡΠ°Π΅Ρ ΡΠ΅Π°Π»ΡΠ½ΡΠΉ ΠΌΠΈΡ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΡΠ΅ΠΌΠ°Π½ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ ΡΠ»ΠΎΠ², ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΡ ΠΈΠ΄Π΅ΠΎΠ»ΠΎΠ³Π΅ΠΌΡ, ΠΊΡΠ»ΡΡΡΡΠΌΡ ΠΈ ΠΏΠΎΠ½ΡΡΠΈΡ ΠΊΠ°ΠΊ ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΠΎ-Π΄ΠΈΡΠΊΡΡΡΠΈΠ²Π½ΡΠ΅ ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΈΠΈ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎ Π·Π½Π°ΡΠΈΠΌΠΎΠ³ΠΎ ΡΠΎΠ±ΡΡΠΈΡ
IGHV3-21 gene expression in patients with b-cell chronic lymphocytic leukemia in Ukraine
The aim of the study was to evaluate the frequency of IGHV3-21 gene usage and its clinical significance for patients with B-cell chronic lymphocytic leukemia (CLL) in Ukraine. Patients and Methods: Immunoglobulin variable heavy chain (IGHV) gene repertoire was studied in 189 CLL patients using reverse transcribed polymerase chain reaction and direct sequence of amplified products. Results: IGHV3-21 gene expression was found in 11 cases (5.8%), and its frequency was intermediate between Scandinavian (11.7%) and Mediterranean CLL (2.9%) cohorts. The most of cases (9 of 11) belonged to subset with heterogeneous HCDR3 (heteroHCDR3 subset), and only 2 cases β to subset with classical short ARDANGMDV motif (homHCDR3 subset). Six IGHV3-21 cases were mutated and 5 cases were unmutated. All unmutated cases (all were from heteroHCDR3 subset) had similarity of their HCDR3s with previously published sequences. The differences in overall (OS), progression-free (PFS) and treatment-free survival (TFS) for IGHV3-21 positive patients in comparison with CLL patients expressing the other IGHV genes were statistically insignificant. These survival parameters were comparable also for CLL patients with mutated IGHV3-21 gene usage and expression the others mutated IGHV genes. But remarkable feature of IGHV3-21 expressing patients was high incidence of solid tumors. They have developed in 4 IGHV3-21 positive cases (36.4%) and in 10 cases with expression of the others IGHV genes (5.6%, p = 0.0002). Furthermore, in small group of 6 patients with mutated IGHV3-21 gene expression, 3 patients had solid tumors and one underwent Richter transformation. Unmutated IGHV3-21 gene expressed patients had worse OS and PFS in comparison with CLL patients that expressed the others unmutated IGHV genes. Conclusion: Presented data are in agrement with the opinion about negative prognostic significance of IGHV3-21 gene expression regardless its mutation status. IGHV3-21 expression was associated with development of secondary solid tumors. Revealed high level of homology in heteroHDR3s subset might suggest about possible antigenic influence also, in addition to homHCDR3 subset that was proposed earlier.Π¦Π΅Π»Ρ: ΠΎΡΠ΅Π½ΠΈΡΡ ΡΠ°ΡΡΠΎΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ Π³Π΅Π½Π° IGHV3-21 ΠΈ Π΅Π³ΠΎ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅ Π΄Π»Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
B-ΠΊΠ»Π΅ΡΠΎΡΠ½ΡΠΌ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΌ
Π»ΠΈΠΌΡΠΎΠ»Π΅ΠΉΠΊΠΎΠ·ΠΎΠΌ (Π₯ΠΠ) Π² Π£ΠΊΡΠ°ΠΈΠ½Π΅. ΠΠΎΠ»ΡΠ½ΡΠ΅ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: ΡΠ΅ΠΏΠ΅ΡΡΡΠ°Ρ Π³Π΅Π½ΠΎΠ² Π²Π°ΡΠΈΠ°Π±Π΅Π»ΡΠ½ΡΡ
ΡΡΠ°ΡΡΠΊΠΎΠ² ΡΡΠΆΠ΅Π»ΡΡ
ΡΠ΅ΠΏΠ΅ΠΉ
ΠΈΠΌΠΌΡΠ½ΠΎΠ³Π»ΠΎΠ±ΡΠ»ΠΈΠ½ΠΎΠ² (IGHV) ΠΈΠ·ΡΡΠ°Π»ΠΈ Ρ 189 Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ Π₯ΠΠ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΠΏΠΎΠ»ΠΈΠΌΠ΅ΡΠ°Π·Π½ΠΎΠΉ ΡΠ΅ΠΏΠ½ΠΎΠΉ ΡΠ΅Π°ΠΊΡΠΈΠΈ Π½Π° Π±Π°Π·Π΅ ΠΎΠ±ΡΠ°ΡΠ½ΠΎΠΉ ΡΡΠ°Π½ΡΠΊΡΠΈΠΏΡΠΈΠΈ
ΠΈ ΠΏΡΡΠΌΠΎΠ³ΠΎ ΡΠΈΠΊΠ²Π΅Π½ΡΠ° Π°ΠΌΠΏΠ»ΠΈΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΏΡΠΎΠ΄ΡΠΊΡΠΎΠ². Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ: ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΡ Π³Π΅Π½Π° IGHV3-21 Π²ΡΡΠ²Π»Π΅Π½Π° Ρ 11 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² (5,8%),
ΡΡΠΎ Π·Π°Π½ΠΈΠΌΠ°Π΅Ρ ΠΏΡΠΎΠΌΠ΅ΠΆΡΡΠΎΡΠ½ΠΎΠ΅ ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠ΅ ΠΌΠ΅ΠΆΠ΄Ρ Π‘ΠΊΠ°Π½Π΄ΠΈΠ½Π°Π²ΡΠΊΠΎΠΉ (11,7%) ΠΈ Π‘ΡΠ΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡΡΠΊΠΎΠΉ (2,9%) ΠΊΠΎΠ³ΠΎΡΡΠ°ΠΌΠΈ. ΠΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²ΠΎ
ΡΠ»ΡΡΠ°Π΅Π² (9 ΠΈΠ· 11) ΠΎΡΠ½ΠΎΡΠΈΠ»ΠΈΡΡ ΠΊ ΠΏΠΎΠ΄Π³ΡΡΠΏΠΏΠ΅ Ρ Π³Π΅ΡΠ΅ΡΠΎΠ³Π΅Π½Π½ΡΠΌ ΡΡΠ΅ΡΡΠΈΠΌ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΌΠ΅Π½ΡΠ°ΡΠ½ΡΠΌΡΠ΅Π³ΠΈΠΎΠ½ΠΎΠΌ (heteroHCDR3 ΠΏΠΎΠ΄Π³ΡΠΏΠΏΠ°) ΠΈ ΡΠΎΠ»ΡΠΊΠΎ
2 ΡΠ»ΡΡΠ°Ρ β ΠΊ ΠΏΠΎΠ΄Π³ΡΡΠΏΠΏΠ΅ Ρ ΠΊΠΎΡΠΎΡΠΊΠΈΠΌ ΠΊΠ»Π°ΡΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ARDANGMDV ΠΌΠΎΡΠΈΠ²ΠΎΠΌ (homHCDR ΡΠΏΠΏΠ°). Π΅ΡΡΡ IGHV3-21-ΠΏΠΎΠ·ΠΈΡΠΈΠ²Π½ΡΡ
ΡΠ»ΡΡΠ°Π΅Π² Π±ΡΠ»ΠΈ ΠΌΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΠΌΠΈ ΠΈ 5 β Π½Π΅ΠΌΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΠΌΠΈ. ΠΡΠ΅ Π½Π΅ΠΌΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΠ΅ ΡΠ»ΡΡΠ°ΠΈ (Π²ΡΠ΅ ΠΈΠ· heteroHCDR ΡΠΏΠΏΡ)
ΠΈΠΌΠ΅Π»ΠΈ ΡΡ
ΠΎΠ΄ΡΡΠ²ΠΎ HCDR3 Ρ Π°Π½Π΅Π΅ ΠΎΠΏΠΈΡΠ°Π½Π½ΡΠΌΠΈ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΡΠΌΠΈ. Π Π°Π·Π»ΠΈΡΠΈΡ Π² ΠΎΠ±ΡΠ΅ΠΉ Π²ΡΠΆΠΈΠ²Π°Π΅ΠΌΠΎΡΡΠΈ (OS), Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ
ΠΏΠ΅ΡΠΈΠΎΠ΄Π° Π΄ΠΎ ΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ (PFS) ΠΈ Π½Π°ΡΠ°Π»Π° Π»Π΅ΡΠ΅Π½ΠΈΡ (TFS) Π΄Π»Ρ IGHV3-21-ΠΏΠΎΠ·ΠΈΡΠΈΠ²Π½ΡΡ
Π±ΠΎΠ»ΡΠ½ΡΡ
Π±ΡΠ»ΠΈ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈ
Π½Π΅Π·Π½Π°ΡΠΈΠΌΡ ΠΏΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°ΠΌΠΈ Ρ Π₯ΠΠ Ρ ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠ΅ΠΉ Π΄ΡΡΠ³ΠΈΡ
IGHV-Π³Π΅Π½ΠΎΠ². Π£ΠΊΠ°Π·Π°Π½Π½ΡΠ΅ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΡ ΡΠ°ΠΊΠΆΠ΅ ΡΡΠ°Π²Π½ΠΈΠ²Π°Π»ΠΈ
ΠΌΠ΅ΠΆΠ΄Ρ Π±ΠΎΠ»ΡΠ½ΡΠΌΠΈ Π₯ΠΠ Ρ ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠ΅ΠΉ ΠΌΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
IGHV3-21- ΠΈ Π΄ΡΡΠ³ΠΈΡ
IGHV-Π³Π΅Π½ΠΎΠ². ΠΡΠ»ΠΈΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠ΅ΡΡΠΎΠΉ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ
ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠ΅ΠΉ IGHV3-Π³Π΅Π½Π° Π±ΡΠ»Π° Π²ΡΡΠΎΠΊΠ°Ρ Π²ΡΡΡΠ΅ΡΠ°Π΅ΠΌΠΎΡΡΡ ΡΠΎΠ»ΠΈΠ΄Π½ΡΡ
ΠΎΠΏΡΡ
ΠΎΠ»Π΅ΠΉ. ΠΠ½ΠΈ ΡΠ°Π·Π²ΠΈΠ»ΠΈΡΡ Π² 4 IGHV3-21-ΠΏΠΎΠ·ΠΈΡΠΈΠ²Π½ΡΡ
ΡΠ»ΡΡΠ°ΡΡ
(36,4%) ΠΈ Π² 10 ΡΠ»ΡΡΠ°ΡΡ
Ρ ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠ΅ΠΉ Π΄ΡΡΠ³ΠΈΡ
IGHV-Π³Π΅Π½ΠΎΠ² (5,6%, p = 0,0002). ΠΡΠΎΠΌΠ΅ ΡΠΎΠ³ΠΎ, Π² Π½Π΅Π±ΠΎΠ»ΡΡΠΎΠΉ Π³ΡΡΠΏΠΏΠ΅ Π±ΠΎΠ»ΡΠ½ΡΡ
(6) Ρ
ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠ΅ΠΉ ΠΌΡΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ IGHV3-21-Π³Π΅Π½Π° Ρ 3 Π²ΠΎΠ·Π½ΠΈΠΊΠ»ΠΈ ΡΠΎΠ»ΠΈΠ΄Π½ΡΠ΅ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΠΈ 1 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° β ΡΠΈΠ½Π΄ΡΠΎΠΌ Π ΠΈΡ
ΡΠ΅ΡΠ°. Π£ Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ
ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠ΅ΠΉ Π½Π΅ΠΌΡΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ IGHV3-21-Π³Π΅Π½Π° ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΠ»ΠΈ Ρ
ΡΠ΄ΡΠΈΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ OS ΠΈ PFS ΠΏΠΎ ΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°ΠΌΠΈ Ρ ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠ΅ΠΉ
Π΄ΡΡΠ³ΠΈΡ
Π½Π΅ΠΌΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
IGHV-Π³Π΅Π½ΠΎΠ². ΠΡΠ²ΠΎΠ΄Ρ: ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π½ΡΠ΅ Π΄Π°Π½Π½ΡΠ΅ ΡΠΎΠ³Π»Π°ΡΡΡΡΡΡ Ρ ΠΌΠ½Π΅Π½ΠΈΠ΅ΠΌ ΠΎ ΡΠ°ΠΌΠΎΡΡΠΎΡΡΠ΅Π»ΡΠ½ΠΎΠΌ
Π½Π΅Π³Π°ΡΠΈΠ²Π½ΠΎΠΌ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠΌ Π·Π½Π°ΡΠ΅Π½ΠΈΠΈ Π΄Π»Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ Π₯ΠΠ ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΠΈ IGHV3-21-Π³Π΅Π½Π° Π²Π½Π΅ Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ Π΅Π³ΠΎ ΠΌΡΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ
ΡΡΠ°ΡΡΡΠ°. IGHV3-21-ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΡ Π±ΡΠ»Π° Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π½Π° Ρ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ Π²ΡΠΎΡΠΈΡΠ½ΡΡ
ΡΠΎΠ»ΠΈΠ΄Π½ΡΡ
ΠΎΠΏΡΡ
ΠΎΠ»Π΅ΠΉ. ΠΡΡΠ²Π»Π΅Π½Π½ΡΠΉ Π²ΡΡΠΎΠΊΠΈΠΉ ΡΡΠΎΠ²Π΅Π½Ρ
Π³ΠΎΠΌΠΎΠ»ΠΎΠ³ΠΈΠΈ Π² heteroHDR3s-ΠΏΠΎΠ΄Π³ΡΡΠΏΠΏΠ΅ ΠΌΠΎΠΆΠ΅Ρ ΡΠ²ΠΈΠ΄Π΅ΡΠ΅Π»ΡΡΡΠ²ΠΎΠ²Π°ΡΡ ΠΎ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΠΌ Π°Π½ΡΠΈΠ³Π΅Π½Π½ΠΎΠΌ Π²Π»ΠΈΡΠ½ΠΈΠΈ Π² Π΄ΠΎΠΏΠΎΠ»Π½Π΅Π½ΠΈΠ΅ ΠΊ Π°Π½ΡΠΈΠ³Π΅Π½Π½ΠΎΠΌΡ
Π²Π»ΠΈΡΠ½ΠΈΡ Π² homHCDR ΡΠΏΠΏΠ΅, ΡΡΠΎ Π±ΡΠ»ΠΎ ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ ΡΠ°Π½Π΅
Dynamic correlations in an ordered c(22) lattice gas
We obtain the dynamic correlation function of two-dimensional lattice gas
with nearest-neighbor repulsion in ordered c(22) phase
(antiferromagnetic ordering) under the condition of low concentration of
structural defects. It is shown that displacements of defects of the ordered
state are responsible for the particle number fluctuations in the probe area.
The corresponding set of kinetic equations is derived and solved in linear
approximation on the defect concentration. Three types of strongly correlated
complex jumps are considered and their contribution to fluctuations is
analysed. These are jumps of excess particles, vacancies and flip-flop jumps.
The kinetic approach is more general than the one based on diffusion-like
equations used in our previous papers. Thus, it becomes possible to adequately
describe correlations of fluctuations at small times, where our previous theory
fails to give correct results. Our new analytical results for fluctuations of
particle number in the probe area agree well with those obtained by Monte Carlo
simulations.Comment: 10 pages, 7 figure
Non-resonant wave front reversal of spin waves used for microwave signal processing
It is demonstrated that non-resonant wave front reversal (WFR) of spin-wave
pulses caused by pulsed parametric pumping can be effectively used for
microwave signal processing. When the frequency band of signal amplification by
pumping is narrower than the spectral width of the signal, the non-resonant WFR
can be used for the analysis of the signal spectrum. In the opposite case the
non-resonant WFR can be used for active (with amplification) filtering of the
input signal.Comment: 4 pages, 3 figure
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