117 research outputs found
Effects of adrenalin on ovarian injury formed by ischemia reperfusion in rats
In this study, the impacts of adrenalin on ovarian injury caused by ischemia reperfusion were investigated in rats. In addition, it’s been investigated whether there is a correlation between adrenergic receptors and oxidant/anti-oxidant and COX1/COX-2 levels. It’s been observed that the COX-2 level that is responsible for MDA and inflammatory reaction (which are the indicators of oxidative stress in ovarian tissue to which ischemia reperfusion was applied) increased and the COX-1 levels that are responsible for GSH (an endogenic anti-oxidant with protective impact) were depressed. Adrenalin has prevented an increase in MDA and COX-2 activity in the ovarian tissue, to which I/R was applied, and prevented a reduction in GSH and COX-1 activity. However, adrenalin failed to prevent an MDA increase in ovarian tissue, to which alpha-2 adrenergic receptor blocker yohimbine was given (I/R formed), and also failed to prevent a GSH and COX-1 decrease. Adrenalin also failed to inhibit the COX-2 activity increase in ovarian tissue, to which beta blocker was applied. As a result, stimulation of the alpha-2 adrenergic receptors in an ovarian tissue causes an anti-oxidant and protective effect, while stimulation of beta-2 adrenergic receptors causes an anti-inflammatory effect. It’s been thought that adrenalin protects the ovarian tissue against ischemia reperfusion by stimulating the alpha-2 and beta-2 adrenergic receptors.Colegio de Farmacéuticos de la Provincia de Buenos Aire
Transitional Care for Patients with Congenital Colorectal Diseases: An EUPSA Network Office, ERNICA, and eUROGEN Joint Venture
Background: Transition of care (TOC; from childhood into adulthood) of patients with anorectal malformations (ARM) and Hirschsprung disease (HD) ensures continuation of care for these patients. The aim of this international study was to assess the current status of TOC and adult care (AC) programs for patients with ARM and HD. Methods: A survey was developed by members of EUPSA, ERN eUROGEN, and ERNICA, including patient representatives (ePAGs), comprising of four domains: general information, general questions about transition to adulthood, and disease-specific questions regarding TOC and AC programs. Recruitment of centres was done by the ERNs and EUPSA, using mailing lists and social media accounts. Only descriptive statistics were reported. Results: In total, 82 centres from 21 different countries entered the survey. Approximately half of them were ERN network members. Seventy-two centres (87.8%) had a self-reported area of expertise for both ARM and HD. Specific TOC programs were installed in 44% of the centres and AC programs in 31% of these centres. When comparing centres, wide variation was observed in the content of the programs. Conclusion: Despite the awareness of the importance of TOC and AC programs, these programs were installed in less than 50% of the participating centres. Various transition and AC programs were applied, with considerable heterogeneity in implementation, content and responsible caregivers involved. Sharing best practice examples and taking into account local and National Health Care Programs might lead to a better continuation of care in the future. Level of Evidence: III
Assessing managerial power theory: A meta-analytic approach to understanding the determinants of CEO compensation
Although studies about the determinants of CEO compensation are ubiquitous, the balance of
evidence for one of the more controversial theoretical approaches, managerial power theory,
remains inconclusive. The authors provide a meta-analysis of 219 U.S.-based studies, focusing
on the relationships between indicators of managerial power and levels of CEO compensation
and CEO pay-performance sensitivities. The results indicate that managerial power theory is
well equipped for predicting core compensation variables such as total cash and total
compensation but less so for predicting the sensitivity of pay to performance. In most situations
where CEOs are expected to have power over the pay setting process, they receive significantly
higher levels of total cash and total compensation. In contrast, where boards are expected to
have more power, CEOs receive lower total cash and total compensation. In addition, powerful
directors also appear to be able to establish tighter links between CEO compensation and firm
performance and can accomplish this even in the face of powerful CEOs. The authors discuss
the implications for theory and research regarding the determinants of executive compensation
The outcomes of two different bulking agents (dextranomer hyaluronic acid copolymer and polyacrylate-polyalcohol copolymer) in the treatment of primary vesico-ureteral reflux
The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children
Jahresverlauf der Luftkonzentration anthropogener und biogener Kohlenwasserstoffe an drei unterschiedlich belasteten bayrischen Waldstandorten.
Boundedly solvable extensions of delay differential operators
We describe all boundedly solvable extensions of minimal operators
generated by first-order linear delay differential operators
in Hilbert spaces of vector-functions on finite intervals.
Also, we study the structure of spectrum of these extensions.
To do this we use methods from operator theory
Konzentrationen biogener und anthropogener Kohlenwasserstoffe im Vertikalprofil eines Fichtenhochwaldes.
Zeeman splitting, Zeeman transitions and optical absorption of an electron confined in spherical quantum dots under the magnetic field
In this study, we present a detailed theoretical investigation of the effect of an externally applied magnetic field on the energy states 1s, 1p, 1d and 1f in the spherical quantum dot with finite and infinite confinement potentials. For both finite and infinite spherical quantum dot, the first four electron energies, Zeeman transition energies between these electronic states and optical absorption coefficients between the related states with and without magnetic field are investigated. The results show that the confinement potential, magnetic field and dot radius have a strong effect on energy states, Zeeman transition energies and absorption coefficients especially in the large dot radii. In the small dot radii, energy levels are relatively insensitive to the magnetic field because the spatial confinement of the electron prevails over the magnetic confinement. As Delta m changes from -1 to +1, the peak positions of the optical absorptions shift to higher energy values (blue shift). The absorption peaks for the infinite quantum dot are localised in higher photon energies those that of the finite quantum dot. The magnetic field causes that the degeneration of energies to be removed and the peak positions of transitions corresponding to Delta m = +1 shift towards to blue in contrast to the cases of Delta m = -1 and Delta m = 0
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