435 research outputs found

    Modeling the evolution of the Milky Way from Gaia DR3

    Get PDF
    Galactic stellar populations are good tracers of the history of the Milky Way. Their study via Gaia astrometric and photometric data should allow to pinpoint the star formation history (SFH) in the disc and halo in a self-consistent dynamical model. Population synthesis models are efficient tools to measure the SFH from the distribution of the stars in the Hess diagram, thanks to different locations of stars according to their age and metallicity. We present the iterative strategy planned to fit the IMF and the SFH of the thin disk using the BGMFast scheme (del Alcazar et al., see poster) based on approximate bayesian computation (ABC) performed with HPC tools and, at the same time, the attempt to keep the self-consistent dynamical model by fitting the gravitational potential of the Milky Way to the stellar kinematics and densities from Gaia data (Robin et al., 2022)

    Diagnostic accuracy of transvaginal sonography for detecting parametrial involvement in women with deep endometriosis: systematic review and meta-analysis

    Get PDF
    Objective: To evaluate the accuracy of transvaginal sonography (TVS) for detecting parametrial deep endometriosis, using laparoscopy as the reference standard. Methods: A search was performed in PubMed/MEDLINE and Web of Science for studies evaluating TVS for detecting parametrial involvement in women with suspected deep endometriosis, as compared with laparoscopy, from January 2000 to December 2020. The Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool was used to evaluate the quality of the studies. Pooled sensitivity, specificity and positive and negative likelihood ratios for TVS in the detection of parametrial deep endometriosis were calculated, and the post-test probability of parametrial deep endometriosis following a positive or negative test was determined. Results: The search identified 134 citations. Four studies, comprising 560 patients, were included in the analysis. The mean prevalence of parametrial deep endometriosis at surgery was 18%. Overall, the pooled estimated sensitivity, specificity and positive and negative likelihood ratios of TVS in the detection of parametrial deep endometriosis were 31% (95% CI, 10–64%), 98% (95% CI, 95–99%), 18.5 (95% CI, 8.8–38.9) and 0.70 (95% CI, 0.46–1.06), respectively. The diagnostic odds ratio was 26 (95% CI, 10–68). Heterogeneity was high. Visualization of a lesion suspected to be parametrial deep endometriosis on TVS increased significantly the post-test probability of parametrial deep endometriosis. Conclusion: TVS has high specificity but low sensitivity for the detection of parametrial deep endometriosis. © 2021 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology
    • 

    corecore