Neodymium isotopes of central Mediterranean phosphatic hardgrounds reveal Miocene paleoceanography

Understanding the causes of the formation of hardgrounds provides insights on the oceanographic evolution of a basin. Phosphate-rich hardground formation interrupted carbonate ramp deposition in the Mediterranean during the Miocene. We analyzed the epsilon(Nd) record of three central Mediterranean hardgrounds to identify the origin of the phosphate-rich waters that formed them within the frame of Mediterranean Miocene paleoceanographic evolution. The Nd isotopes suggest that eastern Mediterranean deep waters were controlled by runoff, in contrast to Atlantic and Indian Ocean waters. This Nd isotope record attests to the weakening of Mediterranean circulation during the Miocene due to closure of the Indian Gateway. Limited exchange with Atlantic shallow seawater led to long residence times for deep waters in the basin. This record indicates the role of upwelling in formation of phosphate hardgrounds and shows the influence of global climate change and local paleoceanographic conditions

Miocene paleoceanographic evolution of the Mediterranean area and carbonate production changes: A review

Abstract Miocene is a key interval in the global climate evolution as well as in the geodynamic evolution of the Mediterranean basin. Therefore, global and regional factors controlled Miocene Mediterranean oceanography, which, in turn, affected carbonate production. In this work, we review the Miocene paleocenographic evolution of the Mediterranean starting from its Sr and Nd isotope records. Secondly, we discuss Mediterranean shallow-water carbonate production changes to identify the role of oceanographic conditions in controlling carbonate systems' evolution. During Aquitanian, Sr and Nd isotope records attest an open Mediterranean, mainly fed by the Indian Ocean. From the late Burdigalian, the intermittent connection with the Indian Ocean changed the overall circulation in the basin, leading to higher residence time of waters and smaller water exchanges with the adjacent oceans. In this newly established paleoceanographic framework, regional factors such as volcanism, significantly affected Mediterranean seawater chemistry. Local tectonics led to the development of small sub-basins in the Eastern Mediterranean, characterized by restricted water exchanges from the Tortonian in the easternmost part, to the early Messinian, as attested by the deviation of the Sr isotope record of the proto-Adriatic basin. Larger Benthic Foraminifera (LBF) assemblages dominated carbonate production in the Aquitanian, while they were the most affected by the Indo-Pacific closure, showing a demise after the Burdigalian. With the LBF demise, red algae and bryozoans dominated carbonate ramps from the middle Miocene to the Tortonian. Bryozoans in particular spread during the Monterey Event, favoured by global and regional factors. During early to middle Miocene, corals formed mounds in the oligophotic zone or coral carpets controlled by local conditions. Conversely, in the late Tortonian-early Messinian, they developed as huge reef complexes in the Western and Central Mediterranean, with the exception of small restricted sub-basins, such as the proto-Adriatic basin, where red algae and small benthic foraminifera persisted

Genetically transformed roots: From plant disease to biotechnological resource

Hairy root syndrome is a disease that is induced by Agrobacterium rhizogenes infection and characterized by a proliferation of excessively branching roots. However, in the past 30 years A. rhizogenes-mediated transformation has also provided a valuable platform for studying biosynthesis pathways in plants. Furthermore, the genetically transformed root cultures are becoming increasingly attractive, cost-effective options for mass-producing desired plant metabolites and expressing foreign proteins. Numerous proof-of-concept studies have demonstrated the feasibility of scaling up hairy-root-based processes while maintaining their biosynthetic potential. Recently, hairy roots have also shown immense potential for applications in phytoremediation, that is, plant-based decontamination of polluted environments. This review highlights recent progress and limitations in the field, and outlines future perspectives for the industrial exploitation of hairy roots.Fil: Georgiev, Milen I.. Bulgarian Academy of Sciences; Bulgaria. Leiden University; Países BajosFil: Agostini, Elizabeth. Universidad Nacional de Río Cuarto; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Ludwig Müller, Jutta. Technische Universitat Dresden; AlemaniaFil: Xu, Jianfeng. University of Arkansas for Medical Sciences; Estados Unido

Inelastic scattering of broadband electron wave packets driven by an intense mid-infrared laser field

Intense, 100 fs laser pulses at 3.2 and 3.6 um are used to generate, by multi-photon ionization, broadband wave packets with up to 400 eV of kinetic energy and charge states up to Xe+6. The multiple ionization pathways are well described by a white electron wave packet and field-free inelastic cross sections, averaged over the intensity-dependent energy distribution for (e,ne) electron impact ionization. The analysis also suggests a contribution from a 4d core excitation in xenon

Appropriate lung management in patients with primary antibody deficiencies

Introduction: Human primary immunodeficiency diseases (PIDs) include a broad spectrum of more than 350 disorders, involving different branches of the immune system and classified as 'rare diseases.' Predominantly antibody deficiencies (PADs) represent more than half of the PIDs diagnosed in Europe and are often diagnosed in the adulthood. Areas covered: Although PAD could first present with autoimmune or neoplastic features, respiratory infections are frequent and respiratory disease represents a relevant cause of morbidity and mortality. Pulmonary complications may be classified as infection-related (acute and chronic), immune-mediated, and neoplastic. Expert opinion: At present, no consensus guidelines are available on how to monitor and manage lung complications in PAD patients. In this review, we will discuss the available diagnostic, prognostic and therapeutic instruments and we will suggest an appropriate and evidence-based approach to lung diseases in primary antibody deficiencies. We will also highlight the possible role of promising new tools and strategies in the management of pulmonary complications. However, future studies are needed to reduce of diagnostic delay of PAD and to better understand lung diseases mechanisms, with the final aim to ameliorate therapeutic options that will have a strong impact on Quality of Life and long-term prognosis of PAD patients

Spatial Descriptions Eliminate the Serial Position Effect

Aims: The present study aims to investigate the occurrence of the serial position effect in the recall of items verbally presented in three different contexts. Background: The serial position effect has been studied with both verbal (e.g., words) and visuospatial (e.g., locations) stimuli but not with verbal-spatial stimuli (i.e., spatial description of an environment). In particular, a spatial description of an environment has both spatial information and a meaningful context. Objective: The objective of the present study is to determine whether the use of different contexts (namely, a classic word list, a spatial description of a room, and a narrative without spatial information) can alter the serial position effect. Methods: Depending on the condition, participants were exposed to a) a list of objects, b) a spatial description of a room containing the same objects; c) a narrative presenting the same objects in lack of spatial information. After this learning phase, participants performed a recognition task. Results: The recognition task revealed different accuracy distributions in the three conditions. In particular, in the spatial description condition, the accuracy distribution did not change across the item position. Conclusion: This result is in line with previous studies with visuospatial stimuli. Thus, it seems that spatial descriptions are a particular kind of verbal stimuli, which are encoded similarly to visuospatial stimuli. Overall, these outcomes support the idea that spatial descriptions elicit a spatial representation, which enhances item retention and eliminates the serial position effect

HLMC Fuel Pin Bundle characterization in CIRCE-ICE pool facility

Abstract. This work, carried out at the DICI of Pisa University, in collaboration with ENEA Brasimone R.C., deals with the analysis and a preliminary discussion of the experimental tests performed in the Integral Circulation Experiment (ICE) configuration of the Circulation Eutectic (CIRCE) facility aiming to investigate the heat transfer in fuel rod bundle. The facility test section basically consists of an electrical bundle (FPS) made up of 37 pins arranged in a hexagonal wrapped lattice with a pitch to diameter ratio of 1.8. Along the FPS active length, two sections were instrumented to monitor the heat transfer coefficient along the bundle as well as the cladding temperatures at different ranks of the sub-channels. In particular, forced circulation condition tests were performed imposing a temperature difference through the FPS and a LBE mass flow rate through the FPS. Nusselt number in the sub-channels was calculated as function of the Peclet number and obtained results were compared to Nusselt numbers computed from correlations available in Heavy Liquid Metals (HLM) literature. Results shown that the Nu is slightly lower in the middle section (section 1) if compared with the ones into the upper section (section 3), and that behaviour is probably due to the turbulence of the flow which seems to be fully developed only in the upper part of the fuel pin bundle. Anyway the Nu number, calculated as function of the Pe number in the range Pe~1500÷3000 (forced circulation condition), matches well the numerical correlation available for HLM fuel pin bundle, (i.e. Ushakov and Mikityuk)

SNARC-like compatibility effects for physical and phenomenal magnitudes: A study on visual illusions

Both numerical and non-numerical magnitudes elicit similar Spatial-Numerical Association of Response Codes (SNARC) effects, with small magnitudes associated with left hand responses and large magnitudes associated with right hand responses (Dehaene, Bossini, Giraux, 1993). In the present study, we investigated whether the phenomenal size of visual illusions elicits the same SNARC-like effect revealed for the physical size of pictorial surfaces. Four experiments were conducted by using the Delboeuf illusion (Experiment 1) and the Kanizsa triangle illusion (Experiments 2, 3 & 4). Experiment 1 suggests the presence of a SNARC-like compatibility effect for the physical size of the inducers, while this effect was not revealed for the phenomenal size of the induced elements, possibly masked by a stronger effect of the inducers. A SNARC-like effect for the phenomenal size of the Kanizsa triangle was revealed when participants directly compared the size of the triangles (Experiment 4). Conversely, when participants performed an indirect task (orientation judgment), the SNARC-like effect was present neither for the illusory nor for the physical displays (Experiments 2 & 3). The effect revealed for the size of illusory triangles was comparable to that of real triangles with physical contours, suggesting that both phenomenal and physical magnitudes similarly elicit SNARC-like effects