2,222 research outputs found
Ballistic spin field-effect transistors: Multichannel effects
We study a ballistic spin field-effect transistor (SFET) with special
attention to the issue of multi-channel effects. The conductance modulation of
the SFET as a function of the Rashba spin-orbit coupling strength is
numerically examined for the number of channels ranging from a few to close to
100. Even with the ideal spin injector and collector, the conductance
modulation ratio, defined as the ratio between the maximum and minimum
conductances, decays rapidly and approaches one with the increase of the
channel number. It turns out that the decay is considerably faster when the
Rashba spin-orbit coupling is larger. Effects of the electronic coherence are
also examined in the multi-channel regime and it is found that the coherent
Fabry-Perot-like interference in the multi-channel regime gives rise to a
nested peak structure. For a nonideal spin injector/collector structure, which
consists of a conventional metallic ferromagnet-thin insulator-2DEG
heterostructure, the Rashba-coupling-induced conductance modulation is strongly
affected by large resonance peaks that arise from the electron confinement
effect of the insulators. Finally scattering effects are briefly addressed and
it is found that in the weakly diffusive regime, the positions of the resonance
peaks fluctuate, making the conductance modulation signal sample-dependent.Comment: 18 pages, 15 figure
Graphitic carbon growth on crystalline and amorphous oxide substrates using molecular beam epitaxy
We report graphitic carbon growth on crystalline and amorphous oxide substrates by using carbon molecular beam epitaxy. The films are characterized by Raman spectroscopy and X-ray photoelectron spectroscopy. The formations of nanocrystalline graphite are observed on silicon dioxide and glass, while mainly sp2 amorphous carbons are formed on strontium titanate and yttria-stabilized zirconia. Interestingly, flat carbon layers with high degree of graphitization are formed even on amorphous oxides. Our results provide a progress toward direct graphene growth on oxide materials
Synchrotron x-ray imaging visualization study of capillary-induced flow and critical heat flux on surfaces with engineered micropillars
Over the last several decades, phenomena related to critical heat flux (CHF) on structured surfaces have received a large amount of attention from the research community. The purpose of such research has been to enhance the safety and efficiency of a variety of thermal systems. A number of theories have been put forward to explain the key CHF enhancement mechanisms on structured surfaces. However, these theories have not been confirmed experimentally because of limitations in the available visualization techniques and the complexity of the phenomena. To overcome these limitations and elucidate the CHF enhancement mechanism on the structured surfaces, we introduce synchrotron x-ray imaging with high spatial (similar to 2 mu m) and temporal (similar to 20,000 Hz) resolutions. This technique has enabled us to confirm that capillary-induced flow is the key CHF enhancement mechanism on structured surfaces.11Ysciescopu
3D garment digitisation for virtual wardrobe using a commodity depth sensor
5-Aminovaleric acid (5AVA) is an important five-carbon platform chemical that can be used for the synthesis of polymers and other chemicals of industrial interest. Enzymatic conversion of L-lysine to 5AVA has been achieved by employing lysine 2-monooxygenase encoded by the davB gene and 5-aminovaleramidase encoded by the davA gene. Additionally, a recombinant Escherichia coli strain expressing the davB and davA genes has been developed for bioconversion of L-lysine to 5AVA. To use glucose and xylose derived from lignocellulosic biomass as substrates, rather than L-lysine as a substrate, we previously examined direct fermentative production of 5AVA from glucose by metabolically engineered E. coli strains. However, the yield and productivity of 5AVA achieved by recombinant E. coli strains remain very low. Thus, Corynebacterium glutamicum, a highly efficient L-lysine producing microorganism, should be useful in the development of direct fermentative production of 5AVA using L-lysine as a precursor for 5AVA. Here, we report the development of metabolically engineered C. glutamicum strains for enhanced fermentative production of 5AVA from glucose.Various expression vectors containing different promoters and origins of replication were examined for optimal expression of Pseudomonas putida davB and davA genes encoding lysine 2-monooxygenase and delta-aminovaleramidase, respectively. Among them, expression of the C. glutamicum codon-optimized davA gene fused with His-Tag at its N-Terminal and the davB gene as an operon under a strong synthetic H promoter (plasmid p36davAB3) in C. glutamicum enabled the most efficient production of 5AVA. Flask culture and fed-batch culture of this strain produced 6.9 and 19.7\ua0g/L (together with 11.9\ua0g/L glutaric acid as major byproduct) of 5AVA, respectively. Homology modeling suggested that endogenous gamma-aminobutyrate aminotransferase encoded by the gabT gene might be responsible for the conversion of 5AVA to glutaric acid in recombinant C. glutamicum. Fed-batch culture of a C. glutamicum gabT mutant-harboring p36davAB3 produced 33.1\ua0g/L 5AVA with much reduced (2.0\ua0g/L) production of glutaric acid.Corynebacterium glutamicum was successfully engineered to produce 5AVA from glucose by optimizing the expression of two key enzymes, lysine 2-monooxygenase and delta-aminovaleramidase. In addition, production of glutaric acid, a major byproduct, was significantly reduced by employing C. glutamicum gabT mutant as a host strain. The metabolically engineered C. glutamicum strains developed in this study should be useful for enhanced fermentative production of the novel C5 platform chemical 5AVA from renewable resources
Cell-free synthesis of functional phospholipase A1 from Serratia sp.
Additional file 1: Figure S1 Gas chromatography analysis of sesame oil incubated with cell-free synthesized PLA1
High-speed infrared phase modulators using short helical pitch ferroelectric liquid crystals
A fast phase modulator based on ferroelectric liquid crystal (FLC) is demonstrated and its performances characterized. For uniform alignment and pure phase modulation, we propose a new FLC device configuration using short helical pitch material and homeotropic alignment structure. This device is driven by periodic in-plane electrode stripes implemented on the surface of both cell substrates. As a result, we have obtained large phase modulation ( \u3e 2 pi at lambda=1.55 mu m) and fast response ( \u3c 200 mu sec)
A Phase II Study of Modified FOLFOX4 for Colorectal Cancer Patients with Peritoneal Carcinomatosis
A Comparative Study on the Efficacy of Covered Metal Stent and Plastic Stent in Unresectable Malignant Biliary Obstruction
Background/AimsThe placement of self expandable metal stent (SEMS) is one of the palliative therapeutic options for patients with unresectable malignant biliary obstruction. The aim of this study was to compare the effectiveness of a covered SEMS versus the conventional plastic stent.MethodsWe retrospectively evaluated 44 patients with unresectable malignant biliary obstruction who were treated with a covered SEMS (21 patients) or a plastic stent (10 Fr, 23 patients). We analyzed the technical success rate, functional success rate, early complications, late complications, stent patency and survival rate.ResultsThere was one case in the covered SEMS group that had failed technically, but was corrected successfully using lasso. Functional success rates were 90.5% in the covered SEMS group and 91.3% in the plastic stent group. There was no difference in early complications between the two groups. Median patency of the stent was significantly prolonged in patients who had a covered SEMS (233.6 days) compared with those who had a plastic stent (94.6 days) (p=0.006). During the follow-up period, stent occlusion occurred in 11 patients of the covered SEMS group. Mean survival showed no significant difference between the two groups (covered SEMS group, 236.9 days; plastic stent group, 222.3 days; p=0.182).ConclusionsThe patency of the covered SEMS was longer than that of the plastic stent and the lasso of the covered SEMS was available for repositioning of the stent
Response: The Effect of an Angiotensin Receptor Blocker on Arterial Stiffness in Type 2 Diabetes Mellitus Patients with Hypertension (Diabetes Metab J 2011;35:236-42)
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