Z-Axis Optomechanical Accelerometer

We demonstrate a z-axis accelerometer which uses waveguided light to sense proof mass displacement. The accelerometer consists of two stacked rings (one fixed and one suspended above it) forming an optical ring resonator. As the upper ring moves due to z-axis acceleration, the effective refractive index changes, changing the optical path length and therefore the resonant frequency of the optical mode. The optical transmission changes with acceleration when the laser is biased on the side of the optical resonance. This silicon nitride "Cavity-enhanced OptoMechanical Accelerometer" (COMA) has a sensitivity of 22 percent-per-g optical modulation for our highest optical quality factor (Q_o) devicesComment: Published in Proceedings of the 25th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2012), Paris, France, January 29 - Feb 2, 2012, pp. 615-61

The two axis motion simulator for the large space simulator at ESTEC (European Space Research and Technology Center)

The Large Space Simulator at the European Space Research and Technology Center (ESTEC) has been recently equipped with a motion simulator capable of handling test items of 5 tons mass and having a volume of 7m in diameter and a length of 7m. The motion simulator has a modular set-up. It consists of a spinbox as a basic unit on which the test article is mounted and which allows continuous rotation (spin) . This spinbox can be used in two operational configurations; the spin axis is vertical to 30 degrees when mounted on a gimbalstand; and the spin axis is horizontal when mounted on a turntable-yoke combination. The turntable provides rotation within plus or minus 90 degrees. This configuration allows one to bring a test article to all possible relative positions viv-a-vis the sun vector (which is horizontal in this case). The spinbox allows fast rotation between 1 to 6 rpm or slow rotation between 1 to 25 rotations per day as well as positioning within plus or minus 0.4 degrees accuracy

Diversification of a protein kinase cascade: IME-2 is involved in nonself recognition and programmed cell death in Neurospora crassa.

Kinase cascades and the modification of proteins by phosphorylation are major mechanisms for cell signaling and communication, and evolution of these signaling pathways can contribute to new developmental or environmental response pathways. The Saccharomyces cerevisiae kinase Ime2 has been well characterized for its role in meiosis. However, recent studies have revealed alternative functions for Ime2 in both S. cerevisiae and other fungi. In the filamentous fungus Neurospora crassa, the IME2 homolog (ime-2) is not required for meiosis. Here we determine that ime-2 interacts genetically with a transcription factor vib-1 during nonself recognition and programmed cell death (PCD). Mutations in vib-1 (Δvib-1) suppress PCD due to nonself recognition events; however, a Δvib-1 Δime-2 mutant restored wild-type levels of cell death. A role for ime-2 in the post-translational processing and localization of a mitochondrial matrix protein was identified, which may implicate mitochondria in N. crassa nonself recognition and PCD. Further, Δvib-1 strains do not produce extracellular proteases, but protease secretion reverted to near wild-type levels in a Δvib-1 Δime-2 strain. Mass spectrometry analysis revealed that the VIB-1 protein is phosphorylated at several sites, including a site that matches the IME-2 consensus. The genetic and biochemical data for ime-2 and vib-1 indicate that IME-2 is a negative regulator of VIB-1 and suggest parallel negative regulation by IME-2 of a cell death pathway in N. crassa that functions in concert with the VIB-1 cell death pathway. Thus, IME2 kinase function has evolved following the divergence of S. cerevisiae and N. crassa and provides insight into the evolution of kinases and their regulatory targets

Rendezvous radar requirements analysis for mission 3B

Data are presented verifying the compatibility of currently proposed rendezvous radar measurement accuracies with Mission 3B rendezvous requirements. In addition, data presented indicate a potential for increasing the acceptable time lag between termination of thrusting and availability of accurate measurement data. Additional investigation is recommended to define any acceptable time lag above the current proposed value. Finally, Mission 3B rendezvous performance is shown to be sensitive to variations in the relative downrange position dispersions at insertion. It is therefore recommended that insertion relative state dispersions used in studies of 3B rendezvous be reviewed when results of 3B ascent dispersion studies are available

Population health profile of the NSW Outback Division of General Practice: supplement

© Commonwealth of Australia To view the data presented in the profiles in Excel spreadsheets or via Interactive Mapping, please see the PHIDU website at: www.publichealth.gov.au

Unsupervised two-class and multi-class support vector machines for abnormal traffic characterization

Although measurement-based real-time traffic classification has received considerable research attention, the timing constraints imposed by the high accuracy requirements and the learning phase of the algorithms employed still remain a challenge. In this paper we propose a measurement-based classification framework that exploits unsupervised learning to accurately categorise network anomalies to specific classes. We introduce the combinatorial use of two-class and multi-class unsupervised Support Vector Machines (SVM)s to first distinguish normal from anomalous traffic and to further classify the latter category to individual groups depending on the nature of the anomaly

Population health profile of the Northern Melbourne Division of General Practice

© Commonwealth of Australia To view the data presented in the profiles in Excel spreadsheets or via Interactive Mapping, please see the PHIDU website at: www.publichealth.gov.au