12 research outputs found
QOS Multimedia Multicast Routing: A Component Based Primal Dual Approach
The QoS Steiner Tree Problem asks for the most cost efficient way to multicast multimedia to a heterogeneous collection of users with different data consumption rates. We assume that the cost of using a link is not constant but rather depends on the maximum bandwidth routed through the link. Formally, given a graph with costs on the edges, a source node and a set of terminal nodes, each one with a bandwidth requirement, the goal is to find a Steiner tree containing the source, and the cheapest assignment of bandwidth to each of its edges so that each source-to-terminal path in the tree has bandwidth at least as large as the bandwidth required by the terminal. Our main contributions are: (1) New flow-based integer linear program formulation for the problem; (2) First implementation of 4.311 primal-dual constant factor approximation algorithm; (3) an extensive experimental study of the new heuristics and of several previously proposed algorithms
The effects of using variable lengths for degraded signal acquisition in GPS receivers
The signal acquisition in GPS receivers is the first and very crucial process that may affect the overall performance of a navigation receiver. Acquisition program initiates a searching operation on received navigation signals to detect and identify the visible satellites. However, signal acquisition becomes a very challenging task in a degraded environment (i.e, dense urban) and the receiver may not be able to detect the satellites present in radio-vicinity, thus cannot estimate an accurate position solution. In such environments, satellite signals are attenuated and fluctuated due to fading introduced by Multipath and NLOS reception. To perform signal acquisition in such degraded environments, larger data accumulation can be effective in enhancing SNR, which tradeoff huge computational load, prolonged acquisition time and high cost of receiver. This paper highlights the effects of fading on satellite signal acquisition in GPS receiver through variable data lengths and SNR comparison, and then develops a statistical relationship between satellite visibility and SNR. Furthermore it also analyzes/investigates the tradeoff between computation load and signal data length
Implementation of ANN Controller Based UPQC Integrated with Microgrid
This study discusses how to increase power quality by integrating a unified power quality conditioner (UPQC) with a grid-connected microgrid for clean and efficient power generation. An Artificial Neural Network (ANN) controller for a voltage source converter-based UPQC is proposed to minimize the system’s cost and complexity by eliminating mathematical operations such as a-b-c to d-q-0 translation and the need for costly controllers such as DSPs and FPGAs. In this study, nonlinear unbalanced loads and harmonic supply voltage are used to assess the performance of PV-battery-UPQC using an ANN-based controller. Problems with voltage, such as sag and swell, are also considered. This work uses an ANN control system trained with the Levenberg-Marquardt backpropagation technique to provide effective reference signals and maintain the required dc-link capacitor voltage. In MATLAB/Simulink software, simulations of PV-battery-UPQC employing SRF-based control and ANN-control approaches are performed. The findings revealed that the proposed approach performed better, as presented in this paper. Furthermore, the influence of synchronous reference frame (SRF) and ANN controller-based UPQC on supply currents and the dc-link capacitor voltage response is studied. To demonstrate the superiority of the suggested controller, a comparison of percent THD in load voltage and supply current utilizing SRF-based control and ANN control methods is shown
Control and Protection of MMC-Based HVDC Systems: A Review
The voltage source converter (VSC) based HVDC (high voltage direct current system) offers the possibility to integrate other renewable energy sources (RES) into the electrical grid, and allows power flow reversal capability. These appealing features of VSC technology led to the further development of multi-terminal direct current (MTDC) systems. MTDC grids provide the possibility of interconnection between conventional power systems and other large-scale offshore sources like wind and solar systems. The modular multilevel converter (MMC) has become a popular technology in the development of the VSC-MTDC system due to its salient features such as modularity and scalability. Although, the employment of MMC converter in the MTDC system improves the overall system performance. However, there are some technical challenges related to its operation, control, modeling and protection that need to be addressed. This paper mainly provides a comprehensive review and investigation of the control and protection of the MMC-based MTDC system. In addition, the issues and challenges associated with the development of the MMC-MTDC system have been discussed in this paper. It majorly covers the control schemes that provide the AC system support and state-of-the-art relaying algorithm/ dc fault detection and location algorithms. Different types of dc fault detection and location algorithms presented in the literature have been reviewed, such as local measurement-based, communication-based, traveling wave-based and artificial intelligence-based. Characteristics of the protection techniques are compared and analyzed in terms of various scenarios such as implementation in CBs, system configuration, selectivity, and robustness. Finally, future challenges and issues regarding the development of the MTDC system have been discussed in detail
Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial
Background
Previous evidence indicates that adjuvant, short-course androgen deprivation therapy (ADT) improves metastasis-free survival when given with primary radiotherapy for intermediate-risk and high-risk localised prostate cancer. However, the value of ADT with postoperative radiotherapy after radical prostatectomy is unclear.
Methods
RADICALS-HD was an international randomised controlled trial to test the efficacy of ADT used in combination with postoperative radiotherapy for prostate cancer. Key eligibility criteria were indication for radiotherapy after radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to radiotherapy alone (no ADT) or radiotherapy with 6 months of ADT (short-course ADT), using monthly subcutaneous gonadotropin-releasing hormone analogue injections, daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as distant metastasis arising from prostate cancer or death from any cause. Standard survival analysis methods were used, accounting for randomisation stratification factors. The trial had 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 80% to 86% (hazard ratio [HR] 0·67). Analyses followed the intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and ClinicalTrials.gov, NCT00541047.
Findings
Between Nov 22, 2007, and June 29, 2015, 1480 patients (median age 66 years [IQR 61–69]) were randomly assigned to receive no ADT (n=737) or short-course ADT (n=743) in addition to postoperative radiotherapy at 121 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 9·0 years (IQR 7·1–10·1), metastasis-free survival events were reported for 268 participants (142 in the no ADT group and 126 in the short-course ADT group; HR 0·886 [95% CI 0·688–1·140], p=0·35). 10-year metastasis-free survival was 79·2% (95% CI 75·4–82·5) in the no ADT group and 80·4% (76·6–83·6) in the short-course ADT group. Toxicity of grade 3 or higher was reported for 121 (17%) of 737 participants in the no ADT group and 100 (14%) of 743 in the short-course ADT group (p=0·15), with no treatment-related deaths.
Interpretation
Metastatic disease is uncommon following postoperative bed radiotherapy after radical prostatectomy. Adding 6 months of ADT to this radiotherapy did not improve metastasis-free survival compared with no ADT. These findings do not support the use of short-course ADT with postoperative radiotherapy in this patient population
Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial
Background
Previous evidence supports androgen deprivation therapy (ADT) with primary radiotherapy as initial treatment for intermediate-risk and high-risk localised prostate cancer. However, the use and optimal duration of ADT with postoperative radiotherapy after radical prostatectomy remains uncertain.
Methods
RADICALS-HD was a randomised controlled trial of ADT duration within the RADICALS protocol. Here, we report on the comparison of short-course versus long-course ADT. Key eligibility criteria were indication for radiotherapy after previous radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to add 6 months of ADT (short-course ADT) or 24 months of ADT (long-course ADT) to radiotherapy, using subcutaneous gonadotrophin-releasing hormone analogue (monthly in the short-course ADT group and 3-monthly in the long-course ADT group), daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as metastasis arising from prostate cancer or death from any cause. The comparison had more than 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 75% to 81% (hazard ratio [HR] 0·72). Standard time-to-event analyses were used. Analyses followed intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and
ClinicalTrials.gov
,
NCT00541047
.
Findings
Between Jan 30, 2008, and July 7, 2015, 1523 patients (median age 65 years, IQR 60–69) were randomly assigned to receive short-course ADT (n=761) or long-course ADT (n=762) in addition to postoperative radiotherapy at 138 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 8·9 years (7·0–10·0), 313 metastasis-free survival events were reported overall (174 in the short-course ADT group and 139 in the long-course ADT group; HR 0·773 [95% CI 0·612–0·975]; p=0·029). 10-year metastasis-free survival was 71·9% (95% CI 67·6–75·7) in the short-course ADT group and 78·1% (74·2–81·5) in the long-course ADT group. Toxicity of grade 3 or higher was reported for 105 (14%) of 753 participants in the short-course ADT group and 142 (19%) of 757 participants in the long-course ADT group (p=0·025), with no treatment-related deaths.
Interpretation
Compared with adding 6 months of ADT, adding 24 months of ADT improved metastasis-free survival in people receiving postoperative radiotherapy. For individuals who can accept the additional duration of adverse effects, long-course ADT should be offered with postoperative radiotherapy.
Funding
Cancer Research UK, UK Research and Innovation (formerly Medical Research Council), and Canadian Cancer Society
Brushless Field Excitation Scheme for Wound Field Synchronous Machines
A new harmonic field excitation technique for the brushless operation of wound field synchronous machines (WFSMs) is proposed in this paper. The proposed scheme involves conventional three-phase and single-phase inverters operating at different frequencies and supply input current to the armature winding simultaneously. This results in a composite output current of the inverters, which contains fundamental as well as the third harmonic current components. The fundamental is utilized to develop the stator field, on the other hand, the third harmonic is used for developing the pulsating magnetomotive force (MMF) in the airgap. This MMF produces a harmonic current in the harmonic winding of the rotor which is later rectified to inject field current to the rotor field winding. The theoretical analysis of the proposed technique is supported using 2-D finite element analysis (FEA)
Polyoxometalates decorated with metal-organic moieties as new molecular photo- and electro-catalysts
Polyoxometalates decorated with metal-organic moieties as new molecular photo- and electro-catalysts
<p>Three new polyoxometalate-based organic-inorganic hybrid compounds (POIHCs), [Cu(PBI)<sub>2</sub>(H<sub>2</sub>O)][{Cu(PBI)(OH)(H<sub>2</sub>O)}{PW<sub>12</sub>O<sub>40</sub>}]·5H<sub>2</sub>O (<b>1</b>), [Cu(PBI)<sub>2</sub>(H<sub>2</sub>O)][{Cu(PBI)<sub>2</sub>(H<sub>2</sub>O)}{SiW<sub>12</sub>O<sub>40</sub>}]·4H<sub>2</sub>O (<b>2</b>) and [Cu<sub>4</sub>(HPO<sub>4</sub>)(PO<sub>4</sub>)(H<sub>2</sub>O)<sub>2</sub>(PBI)<sub>4</sub>][PMo<sub>12</sub>O<sub>40</sub>]·H<sub>2</sub>O (<b>3</b>) (PBI =2-(pyridin-2-yl)-1H-benzo[d]imidazole), have been synthesized under hydrothermal conditions. All three compounds were characterized by elemental analysis, IR spectroscopy, thermogravimetric analysis, powder X-ray diffraction and single-crystal X-ray diffraction. In <b>1</b> and <b>2</b>, the Keggin-type polyoxometalate (POM) units are decorated by the {Cu/PBI} metal-organic fragments, together with additional {Cu/PBI} isolated cations, which further stack into 3-D supramolecular frameworks with porous structural features. Compound <b>3</b> consists of a rare cationic cluster [Cu<sub>4</sub>(HPO<sub>4</sub>)(PO<sub>4</sub>)(H<sub>2</sub>O)<sub>2</sub>(PBI)<sub>4</sub>]<sup>3+</sup> and the Keggin-type POM anion, forming a 3-D supramolecular framework with limited interspaces for the entry of guest molecules. Comparable photocatalytic properties of <b>1</b>–<b>3</b> were investigated by the use of methylene blue (MB) and Rhodamine B (RhB) degradation under UV light. All compounds showed good catalytic activity for the degradation of MB in contrast to RhB. The possible catalytic mechanism was discussed based on the size of dye molecules, the low adsorption ability and crystal packing mode of the as-synthesized compounds. Additionally, the electrochemical properties of <b>1</b>–<b>3</b> have also been investigated, exhibiting good electrocatalytic performance for nitrite reduction.</p