7,321 research outputs found
Directionally solidified lamellar eutectic superalloys by edge-defined, film-fed growth
A program was performed to scale up the edge-defined, film-fed growth (EFG) method for the gamma/gamma prime-beta eutectic alloy of the nominal composition Ni-19.7 Cb - 6 Cr-2.5 Al. Procedures and problem areas are described. Flat bars approximately 12 x 1.7 x 200 mm were grown, mostly at speeds of 38 mm/hr, and tensile tests on these bars at 25 and 1000 C showed lower strength than expected. The feasibility of growing hollow airfoils was also demonstrated by growing bars over 200 mm long with a teardrop shaped cross-section, having a major dimension of 12 mm and a maximum width of 5 mm
The Ulysses Supplement to the BATSE 3B Catalog of Cosmic Gamma-Ray Bursts
We present Interplanetary Network localization information for 218 gamma-ray
bursts in the 3rd BATSE catalog, obtained by analyzing the arrival times of
these bursts at the Ulysses and Compton Gamma-Ray Observatory (CGRO)
spacecraft. For any given burst observed by these two spacecraft, arrival time
analysis (or "triangulation") results in an annulus of possible arrival
directions whose half-width varies between 7 arcseconds and 32 arcminutes,
depending on the intensity and time history of the burst, and the distance of
the Ulysses spacecraft from Earth. This annulus generally intersects the BATSE
error circle, resulting in an average reduction of the error box area of a
factor of 30.Comment: Accepted for publication in the Astrophysical Journal Supplemen
The Interplanetary Network Supplement to the BeppoSAX Gamma-Ray Burst Catalogs
Between 1996 July and 2002 April, one or more spacecraft of the
interplanetary network detected 787 cosmic gamma-ray bursts that were also
detected by the Gamma-Ray Burst Monitor and/or Wide-Field X-Ray Camera
experiments aboard the BeppoSAX spacecraft. During this period, the network
consisted of up to six spacecraft, and using triangulation, the localizations
of 475 bursts were obtained. We present the localization data for these events.Comment: 89 pages, 3 figures. Submitted to the Astrophysical Journal
Supplement Serie
TREEOME: A framework for epigenetic and transcriptomic data integration to explore regulatory interactions controlling transcription
Motivation: Predictive modelling of gene expression is a powerful framework
for the in silico exploration of transcriptional regulatory interactions
through the integration of high-throughput -omics data. A major limitation of
previous approaches is their inability to handle conditional and synergistic
interactions that emerge when collectively analysing genes subject to different
regulatory mechanisms. This limitation reduces overall predictive power and
thus the reliability of downstream biological inference.
Results: We introduce an analytical modelling framework (TREEOME: tree of
models of expression) that integrates epigenetic and transcriptomic data by
separating genes into putative regulatory classes. Current predictive modelling
approaches have found both DNA methylation and histone modification epigenetic
data to provide little or no improvement in accuracy of prediction of
transcript abundance despite, for example, distinct anti-correlation between
mRNA levels and promoter-localised DNA methylation. To improve on this, in
TREEOME we evaluate four possible methods of formulating gene-level DNA
methylation metrics, which provide a foundation for identifying gene-level
methylation events and subsequent differential analysis, whereas most previous
techniques operate at the level of individual CpG dinucleotides. We demonstrate
TREEOME by integrating gene-level DNA methylation (bisulfite-seq) and histone
modification (ChIP-seq) data to accurately predict genome-wide mRNA transcript
abundance (RNA-seq) for H1-hESC and GM12878 cell lines.
Availability: TREEOME is implemented using open-source software and made
available as a pre-configured bootable reference environment. All scripts and
data presented in this study are available online at
http://sourceforge.net/projects/budden2015treeome/.Comment: 14 pages, 6 figure
Gravitationally Lensed Gamma-Ray Bursts as Probes of Dark Compact Objects
If dark matter in the form of compact objects comprises a large fraction of
the mass of the universe, then gravitational lensing effects on gamma-ray
bursts are expected. We utilize BATSE and Ulysses data to search for lenses of
different mass ranges, which cause lensing in the milli, pico, and femto
regimes. Null results are used to set weak limits on the cosmological abundance
of compact objects in mass ranges from 10 to 10 . A
stronger limit is found for a much discussed universe dominated
by black holes of masses , which is ruled out at the
90% confidence level.Comment: 14 pages, 4 figures, fixed minor corrections. Accepted for
publication in ApJ(L
The distances of short-hard GRBs and the SGR connection
We present a search for nearby (D<100 Mpc) galaxies in the error boxes of six
well-localized short-hard gamma-ray bursts (GRBs). None of the six error boxes
reveals the presence of a plausible nearby host galaxy. This allows us to set
lower limits on the distances and, hence, the isotropic-equivalent energy of
these GRBs. Our lower limits are around erg (at
confidence level); as a consequence, some of the short-hard GRBs we examine
would have been detected by BATSE out to distances greater than 1 Gpc and
therefore constitute a bona fide cosmological population. Our search is
partially motivated by the December 27, 2004 hypergiant flare from SGR 1806-20,
and the intriguing possibility that short-hard GRBs are extragalactic events of
a similar nature. Such events would be detectable with BATSE to a distance of
\~50 Mpc, and their detection rate should be comparable to the actual BATSE
detection rate of short-hard GRBs. The failure of our search, by contrast,
suggests that such flares constitute less than 15% of the short-hard GRBs (<40%
at 95% confidence). We discuss possible resolutions of this discrepancy.Comment: Enlarged sample of bursts; ApJ in pres
The Ulysses Supplement to the BATSE 4Br Catalog of Cosmic Gamma-Ray Bursts
We present Interplanetary Network localization information for 147 gamma-ray
bursts observed by the Burst and Transient Source Experiment between the end of
the 3rd BATSE catalog and the end of the 4th BATSE catalog, obtained by
analyzing the arrival times of these bursts at the Ulysses and Compton
Gamma-Ray Observatory (CGRO) spacecraft. For any given burst observed by these
two spacecraft, arrival time analysis (or "triangulation") results in an
annulus of possible arrival directions whose half-width varies between 7
arcseconds and 2.3 degrees, depending on the intensity and time history of the
burst, and the distance of the Ulysses spacecraft from Earth. This annulus
generally intersects the BATSE error circle, resulting in an average reduction
of the error box area of a factor of 25.Comment: Accepted for publication in the Astrophysical Journal Supplemen
Study for evaluation of incineration and microwave treatment of human fecal matter for spacecraft operation
Incineration and microwave treatment of human fecal matter to determine concentration ranges and identities of liquid, gaseous, and solid product
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