3,054 research outputs found

    Nonlinear surface plasmons

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    We derive an asymptotic equation for quasi-static, nonlinear surface plasmons propagating on a planar interface between isotropic media. The plasmons are nondispersive with a constant linearized frequency that is independent of their wavenumber. The spatial profile of a weakly nonlinear plasmon satisfies a nonlocal, cubically nonlinear evolution equation that couples its left-moving and right-moving Fourier components. We prove short-time existence of smooth solutions of the asymptotic equation and describe its Hamiltonian structure. We also prove global existence of weak solutions of a unidirectional reduction of the asymptotic equation. Numerical solutions show that nonlinear effects can lead to the strong spatial focusing of plasmons. Solutions of the unidirectional equation appear to remain smooth when they focus, but it is unclear whether or not focusing can lead to singularity formation in solutions of the bidirectional equation

    Modelling micro-scale coalescence and transportprocesses in liquid aerosol filtration

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    This work has examined the physico-chemical properties of coalescing filters on a micro-scale, considering them as either a capillary system or a fibre-droplet system. This work has developed a validated theoretical model for droplet-fibe forces in both phillic and phobic systems and a computational fluid dynamics solver for droplet-fibre systems. This work will significantly improve the design and optimisation of coalescing filter systems

    Sex Differences with Aging in the Fatigability of Dynamic Contractions

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    This study determined the sex difference with aging in fatigability of the elbow flexor muscles during a dynamic fatiguing task, and explored the associated mechanisms. We compared fatigability of the elbow flexor muscles in 18 young (20.2 ± 1 years: 9 men) and 36 old adults (73.5 ± 1 years: 16 men) during and in recovery from repeated dynamic contractions (~ 60°/s) with a load equivalent to 20% of maximal voluntary isometric contraction (MVIC) torque until failure. Transcranial magnetic stimulation (TMS) was used to assess supraspinal fatigue (an increase in the superimposed twitch, SIT) and the peak rate of muscle relaxation. Time to failure was briefer for the men than the women (6.1 ± 2.1 vs. 9.7 ± 5.5 min, respectively; P = 0.02) with no difference between young and old adults (7.2 ± 2.9 vs. 8.4 ± 5.2 min, respectively, P = 0.45) and no interaction (P \u3e 0.05). The relative decline in peak relaxation rate with fatigability was similar for young and old adults (P = 0.11), but greater for men than women (P = 0.046). Supraspinal fatigue increased for all groups and was associated with the time to failure (P \u3c 0.05). Regression analysis however, indicated that the time to failure was best predicted by the peak relaxation rate (baseline values and slowing with fatigability) (r2 = 0.55). Rate-limiting contractile mechanisms (e.g. excitation–contraction coupling) were responsible for the increased fatigability of the elbow flexors of men compared with women for a dynamic fatiguing task of slow angular velocity, and this sex difference was maintained with aging. The age difference in fatigability for the dynamic task was diminished for both sexes relative to what is typically observed with isometric fatiguing contractions

    Gas micro-well track imaging detectors for gamma-ray astronomy

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    We describe our program to develop gas micro-well detectors (MWDs) as three-dimensional charged particle trackers for use in advanced gamma-ray telescope concepts. A micro-well detector consists of an array of individual micro-patterned gas proportional counters opposite a planar drift electrode. The well anodes and cathodes may be connected in X and Y strips, respectively, to provide two-dimensional imaging. When combined with transient digitizer electronics, which record the time signature of the charge collected in the wells of each strip, full three-dimensional reconstruction of charged-particle tracks in large gas volumes is possible. Such detectors hold great promise for advanced Compton telescope (ACT) and advanced pair telescope (APT) concepts due to the very precise measurement of charged particle momenta that is possible (Compton recoil electrons and electron-positron pairs, respectively). We present preliminary lab results, including detector fabrication, prototype electronics, and initial detector testing. We also discuss applications to the ACT and APT mission concepts, based on GEANT3 and GEANT4 simulations

    A Putative ABC Transporter, HatABCDE, Is among Molecular Determinants of Pyomelanin Production in Pseudomonas aeruginosa

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    Pyomelanin overproduction is a common phenotype among Pseudomonas aeruginosa isolates recovered from cystic fibrosis and urinary tract infections. Its prevalence suggests that it contributes to the persistence of the producing microbial community, yet little is known about the mechanisms of its production. Using transposon mutagenesis, we identified factors that contribute to melanogenesis in a clinical isolate of P. aeruginosa. In addition to two enzymes already known to be involved in its biosynthesis (homogentisate dioxygenase and hydroxyphenylpyruvate dioxygenase), we identified 26 genes that encode regulatory, metabolic, transport, and hypothetical proteins that contribute to the production of homogentisic acid (HGA), the monomeric precursor of pyomelanin. One of these, PA14_57880, was independently identified four times and is predicted to encode the ATP-binding cassette of an ABC transporter homologous to proteins in Pseudomonas putida responsible for the extrusion of organic solvents from the cytosol. Quantification of HGA production by P. aeruginosa PA14 strains missing the predicted subcomponents of this transporter confirmed its role in HGA production: mutants unable to produce the ATP-binding cassette (PA14_57880) or the permease (PA14_57870) produced substantially less extracellular HGA after growth for 20 h than the parental strain. In these mutants, concurrent accumulation of intracellular HGA was observed. In addition, quantitative real-time PCR revealed that intracellular accumulation of HGA elicits upregulation of these transport genes. Based on their involvement in homogentisic acid transport, we rename the genes of this operon hatABCDE

    A Review of the Operational Use of UAS in Public Safety Emergency Incidents

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    The domain of public safety in the form of search \& rescue, wildland firefighting, structure firefighting, and law enforcement operations have drawn great interest in the field of aerospace engineering, human-robot teaming, autonomous systems, and robotics. However, a divergence exists in the assumptions made in research and how state-of-the-art technologies may realistically transition into an operational capacity. To aid in the alignment between researchers, technologists, and end users, we aim to provide perspective on how small Uncrewed Aerial Systems (sUAS) have been applied in 114 real world incidents as part of a technical rescue team from 2016 to 2021. We highlight the main applications, integration, tasks, and challenges of employing UAS within five primary use cases including searches, evidence collection, SWAT, wildland firefighting, and structure firefighting. Within these use cases, key incidents are featured that provide perspective on the evolving and dynamic nature of UAS tasking during an operation. Finally, we highlight key technical directions for improving the utilization and efficiency of employing aerial technology in all emergency types.Comment: Accepted to the International Conference of Unmanned Aerial Systems (ICUAS) 202

    Development and Validation of a Computational Fluid Dynamics (CFD) Solver for Droplet-Fibre Systems

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    Droplet-fibre interactions are found in many natural and anthropogenic systems. A common industrial example is fibrous filtration - used to capture liquid (e.g. oil) mists. The filters used consist mostly of highly porous arrays of randomly layered fibres. Given the random (complex) nature of these filters, the existing models describing their behaviour are mainly empirical in nature and thus only applicable over a narrow range of parameters and operating conditions. Therefore simulation of these filters using computational fluid dynamics offers a viable alternative to the existing models. In this work we will detail the development of a solver that couples the Lagrangian tracking of particles with a volume-of-fluid (VOF) solver. This solver is built on the existing open-source OpenFOAM CFD libraries, which have been modified to allow the physically accurate modelling of small particles. The solver also models the collection of these particles, where there is a transition from the discrete treatment (as in the Lagrangian tracking of the particles) to the volume-of-fluid treatment. The solver allows the simulation of the motion of small liquid droplets, the capture of these droplets by filter fibres, the coalescence of these captured droplets, into films and the subsequent break up of these films into droplet arrays by Plateau-Rayleigh instability. Also simulated is the movement of these coalesced droplets within the filter, leading to the drainage of oil from the filter.A validation of the fundamental physical mechanisms in the filter was performed, by comparing the simulated conformation of liquid droplets and films on the fibre to Plateau-Rayleigh instability theory. The model showed general agreement with both theory and observations. The simulated capture efficiency was also compared to capture efficiencies predicted by the single fibre efficiency (SFE) theory. A good agreement between the two was found

    Comparison of breathing models for determining flow and particle deposition in the lungs

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    Collection and deposition of particles in the upper airway and lungs is of considerable importance – for example, when studying chronic diseases, or when determining the efficacy of aerosol drug delivery. Modelling of particle deposition usually assumes either constant flow (typically at maximum inspiration), or oscillating flow – ignoring any effects of the lung’s motion. This paper presents a preliminary examination of the effects of ignoring mesh motion when modelling the lungs. Initially, an idealised lung model was created, corresponding to generations 0 to 3 of Weibel’s morphology[14]. Simulations were then made using this geometry for steady flow, oscillating flow, and flow developed by expanding the lung. The expansion of the lung was modelled using a mesh motion library developed by the authors. This model allowed the expansion of the lung to be prescribed. Results from the simulations show significant differences between the three modelling options – relating to both the predicted flow field, and particle deposition sites. Robustness of the moving mesh modelling technique is demonstrated on a high-resolution geometry created from CT scans of a Sprague-Dawley rat model lung
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