21 research outputs found

    Better Pumps: Promoting Reliable Water Infrastructure for Everyone

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    Approximately 90 million people in Africa lack access to safe drinking water, despite having water infrastructure installed in their community. The India Mark II and the Afridev handpumps are among the most widely used handpumps in the world. Sadly, studies show that approximately 30% of these handpumps are non-operational due to failures of the bearings, seals, head flange, and other common components. The Better Pumps team of the Collaboratory provides engineering support for partners who are working to improve handpump sustainability. We have partnered with Tony Beers and AlignedWorks to validate a bearing test methodology for the India Mark II handpump. By modifying the loading conditions in our handpump test machine, we were able to replicate failures observed by AlignedWorks in a field trial of their bearing design. However, these modifications caused our test machine tabletop to noticeably deflect, so we made modifications to stiffen the tabletop. We partnered with Matt Schwiebert and Living Water International to test new seal designs for the India Mark II and Afridev handpumps. Seal performance data collected by the team was used to validate a new design in advance of field trials by Living Water International. We developed and performed clear cylinder testing on the seals to visualize the leak paths. A new Afridev testing apparatus is being designed to test the longevity of the Afridev bearings and seals. Test methodologies and results are reported. Funding for this work provided by The Collaboratory for Strategic Partnerships and Applied Research.https://mosaic.messiah.edu/engr2022/1000/thumbnail.jp

    Regen med therapeutic opportunities for fighting COVID-19.

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    This perspective from a Regenerative Medicine Manufacturing Society working group highlights regenerative medicine therapeutic opportunities for fighting COVID-19. This article addresses why SARS-CoV-2 is so different from other viruses and how regenerative medicine is poised to deliver new therapeutic opportunities to battle COVID-19. We describe animal models that depict the mechanism of action for COVID-19 and that may help identify new treatments. Additionally, organoid platforms that can recapitulate some of the physiological properties of human organ systems, such as the lungs and the heart, are discussed as potential platforms that may prove useful in rapidly screening new drugs and identifying at-risk patients. This article critically evaluates some of the promising regenerative medicine-based therapies for treating COVID-19 and presents some of the collective technologies and resources that the scientific community currently has available to confront this pandemic

    Better Pumps: Reliable Handpump Infrastructure

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    Approximately 90 million people in Africa lack access to safe drinking water, despite having water infrastructure installed in their community. The India Mark II and the Afridev handpumps are among the most widely used handpumps in the world. Sadly, studies show that approximately 30% of these handpumps are non-operational due to failures of the bearings, seals, head flange, and other common components. The Better Pumps team of the Collaboratory provides engineering support for partners who are working to improve handpump sustainability. We partnered with Tony Beers and AlignedWorks to validate a bearing test methodology for the India Mark II handpump. By modifying the loading conditions in our handpump test machine, we were able to replicate failures observed by AlignedWorks in a field trial of their bearing design. We partnered with Matt Schwiebert and Living Water International to test new seal designs for the India Mark II and Afridev handpumps and to measure head flange deflections in the India Mark II handpump. Seal performance data collected by the team was used to validate a new design in advance of field trials by Living Water International. Head flange deflection data was collected for partner benchmarking of their computational analysis. Test methodologies and results are reported.https://mosaic.messiah.edu/engr2021/1000/thumbnail.jp

    Cytocentric measurement for regenerative medicine

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    Any Regenerative Medicine (RM) business requires reliably predictable cell and tissue products. Regulatory agencies expect control and documentation. However, laboratory tissue production is currently not predictable or well-controlled. Before conditions can be controlled to meet the needs of cells and tissues in culture for RM, we have to know what those needs are and be able to quantify them. Therefore, identification and measurement of critical cell quality attributes at a cellular or pericellular level is essential to generating reproducible cell and tissue products. Here, we identify some of the critical cell and process parameters for cell and tissue products as well as technologies available for sensing them. We also discuss available and needed technologies for monitoring both 2D and 3D cultures to manufacture reliable cell and tissue products for clinical and non-clinical use. As any industry matures, it improves and standardizes the quality of its products. Cytocentric measurement of cell and tissue quality attributes are needed for RM

    Retraining investment for Alberta’s oil and gas workers for green jobs in the solar industry

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    Abstract If oil sands are to be eliminated from the energy market to protect the global environment, human health and long-term economic welfare, a significant number of workers will be displaced in the transition to renewable energy technologies. This study outlines a cost-effective and convenient path for oil and gas workers in Alberta to be retrained in the burgeoning solar photovoltaic (PV) industry. Many oil and gas workers would be able to transfer fields with no additional training required. This study examines retraining options for the remainder of workers using the most closely matching skill equivalent PV job to minimize retraining time. The costs for retraining all oil sands workers are quantified and aggregated. The results show the total costs for retaining all oil sands workers in Alberta for the PV industry ranges between CAD91.5 mandCAD91.5 m and CAD276.2 m. Thus, only 2–6% of federal, provincial, and territorial oil and gas subsidies for a single year would need to be reallocated to provide oil and gas workers with a new career of approximately equivalent pay. The results of this study clearly show that a rapid transition to sustainable energy production is feasible as costs of retraining oil and gas workers are far from prohibitive
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