A Guide to Motion and Newton\u27s Laws for General Science

This project provides activities in motion and Newton\u27s Laws of motion. Besides instructions on how to perform the activity, a list of student selfassessment questions is provided to encourage further inquiry. The activities are also aligned with the Essential Academic Learning Requirements for the State of Washington. These activities are designed to supplement curriculum already being taught

Quantifying the Bull's Eye Effect

We have used N-body simulations to develop two independent methods to quantify redshift distortions known as the Bull's Eye effect (large scale infall plus small scale virial motion). This effect depends upon the mass density, $\Omega_0$, so measuring it can in principle give an estimate of this important cosmological parameter. We are able to measure the effect and distinguish between its strength for high and low values of $\Omega_0$. Unlike other techniques which utilize redshift distortions, one of our methods is relatively insensitive to bias. In one approach, we use path lengths between contour crossings of the density field. The other is based upon percolation. We have found both methods to be successful in quantifying the effect and distinguishing between values of $\Omega_0$. However, only the path lengths method exhibits low sensitivity to bias.Comment: 21 pages, 5 figures, 3 tables; Replaced version - minor corrections, replaced figure 2; To appear in ApJ, Jan. 20, 200

Science Education for Citizenship and a Sustainable Future

In this article Jerry Wellington argues very strongly in favour of the role of science in citizenship education. He emphasizes the need for knowledge, skills and action and suggests areas and ways in which pupils can be engaged in the struggle for a sustainable future where interdependence and interconnectedness mesh well with notions of equity and justice

Regulation of the retinoblastoma proteins by the human herpesviruses

Viruses are obligate intracellular parasites that alter the environment of infected cells in order to replicate more efficiently. One way viruses achieve this is by modulating cell cycle progression. The main regulators of progression out of G0, through G1, and into S phase are the members of the retinoblastoma (Rb) family of tumor suppressors. Rb proteins repress the transcription of genes controlled by the E2F transcription factors. Because the expression of E2F-responsive genes is required for cell cycle progression into the S phase, Rb arrests the cell cycle in G0/G1. A number of viral proteins directly target Rb family members for inactivation, presumably to create an environment more hospitable for viral replication. Such viral proteins include the extensively studied oncoproteins E7 (from human papillomavirus), E1A (from adenovirus), and the large T (tumor) antigen (from simian virus 40). Elucidating how these three viral proteins target and inactivate Rb has proven to be an invaluable approach to augment our understanding of both normal cell cycle progression and carcinogenesis. In addition to these proteins, a number of other virally-encoded inactivators of the Rb family have subsequently been identified including a surprising number encoded by human herpesviruses. Here we review how the human herpesviruses modulate Rb function during infection, introduce the individual viral proteins that directly or indirectly target Rb, and speculate about what roles Rb modulation by these proteins may play in viral replication, pathogenesis, and oncogenesis

A Study of Sorghum with Reference to the Content of HCN

Farmers and others concerned with the production and feeding of forage crops long have known that certain crop plants may be poisonous to animals. It also has been found that the poisonous property of certain plants consists of or is associated with prussic acid or hydrocyanic acid (HCN). The research reported in this bulletin are concerned with one principal forage crop, namely sorghum and its varieties

Experimental and numerical cross-validation of flow in real porous media. Part 1: Experimental framework

International audienceIn this study, we present the design of a purpose-built test cell, capable of closely mimicking boundary conditions which can be routinely imposed in fluid flow simulators. The test cell permits conducting systematic studies on the influence of unresolved pore-scale wall-roughness and pore space morphology on the hydraulic conductivity: it is therefore an ideal instrument for the generation of validation datasets for the next generation numerical flow models