Weak Gel Flooding Research and Effect Assessment of Horizontal Injection-Production Well Groups in Light Level of Oilfields

Weak gel flooding has been tested and achieved good results in Bohai heavy oilfields. Based on the mechanism analysis and numerical simulation study, weak gel flooding technology is believed to be effect of increasing oil and decreasing water in light oilfields. BZ S oilfield is a low-viscosity oilfield based on horizontal wells development. Due to different production online time and production rate of the well groups of injection and production horizontal wells, it caused advantageous channels formed between injection and production wells in some groups, which reduce storage rate of injection water and affect the development effect. In order to suppress the injected water onrush along the high permeability layer and improve water-oil mobility ratio and sweep efficiency, we have selected two groups for the weak gel flooding test. After flooding test, we evaluate and analyze the recovery and injection characteristics. It shows the test did not achieve the expected result. Therefore, we sum up reasons for the defeat. First, for horizontal injection wells, weak gel plugged well section of relatively pool physical property around water injection wells, increase of wellhead pressure for injection wells make it difficult to meet the requirements of injection allocation. Second, weak gel is hard to work for the pattern of spacing greater than 400m. For these two reasons, weak gel is not displaced and injected to the deep reservoir, and superior channel is still existed, not present precipitation increased the effect of oil wells. Through the evaluation and failure analysis of this displacement test, we proposed technical requirements for weak gel flooding on the horizontal group of injection and production wells. It provided practical experience and references for the other oilfields EOR tertiary oil recovery programs

Development of a synchronous recording and photo-stimulating electrode in multiple brain neurons

The investigation of brain networks and neural circuits involves the crucial aspects of observing and modulating neurophysiological activity. Recently, opto-electrodes have emerged as an efficient tool for electrophysiological recording and optogenetic stimulation, which has greatly facilitated the analysis of neural coding. However, implantation and electrode weight control have posed significant challenges in achieving long-term and multi-regional brain recording and stimulation. To address this issue, we have developed a mold and custom-printed circuit board-based opto-electrode. We report successful opto-electrode placement and high-quality electrophysiological recordings from the default mode network (DMN) of the mouse brain. This novel opto-electrode facilitates synchronous recording and stimulation in multiple brain regions and holds promise for advancing future research on neural circuits and networks

Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate

Assays that can determine the response of tumor cells to cancer therapeutics could greatly aid the selection of drug regimens for individual patients. However, the utility of current functional assays is limited, and predictive genetic biomarkers are available for only a small fraction of cancer therapies. We found that the single-cell mass accumulation rate (MAR), profiled over many hours with a suspended microchannel resonator, accurately defined the drug sensitivity or resistance of glioblastoma and B-cell acute lymphocytic leukemia cells. MAR revealed heterogeneity in drug sensitivity not only between different tumors, but also within individual tumors and tumor-derived cell lines. MAR measurement predicted drug response using samples as small as 25 μl of peripheral blood while maintaining cell viability and compatibility with downstream characterization. MAR measurement is a promising approach for directly assaying single-cell therapeutic responses and for identifying cellular subpopulations with phenotypic resistance in heterogeneous tumors.United States. National Institutes of Health (R01 CA170592)United States. National Institutes of Health (R33 CA191143)National Cancer Institute (U.S.) (U54 CA143874)United States. National Institutes of Health (NIH/NIGMS T32 GM008334

Assessing Singapore government's new responsible gambling initiatives for casino operations

To assess the efficiency and sufficiency of Singapore government responsible gambling initiatives for upcoming Casinos as well as to provide social safeguard recommendations to further complement the existing regulation

Triboelectric–Electromagnetic Hybrid Generator for Harvesting Blue Energy

Abstract Progress has been developed in harvesting low-frequency and irregular blue energy using a triboelectric–electromagnetic hybrid generator in recent years. However, the design of the high-efficiency, mechanically durable hybrid structure is still challenging. In this study, we report a fully packaged triboelectric–electromagnetic hybrid generator (TEHG), in which magnets were utilized as the trigger to drive contact–separation-mode triboelectric nanogenerators (CS-TENGs) and coupled with copper coils to operate rotary freestanding-mode electromagnetic generators (RF-EMGs). The magnet pairs that produce attraction were used to transfer the external mechanical energy to the CS-TENGs, and packaging of the CS-TENG part was achieved to protect it from the ambient environment. Under a rotatory speed of 100 rpm, the CS-TENGs enabled the TEHG to deliver an output voltage, current, and average power of 315.8 V, 44.6 μA, and ~ 90.7 μW, and the output of the RF-EMGs was 0.59 V, 1.78 mA, and 79.6 μW, respectively. The cylinder-like structure made the TEHG more easily driven by water flow and demonstrated to work as a practical power source to charge commercial capacitors. It can charge a 33 μF capacitor from 0 to 2.1 V in 84 s, and the stored energy in the capacitor can drive an electronic thermometer and form a self-powered water-temperature sensing system

Media 3: Different polarization dynamic states in a vector Yb-doped fiber laser

Originally published in Optics Express on 20 April 2015 (oe-23-8-10747

Media 1: Different polarization dynamic states in a vector Yb-doped fiber laser

Originally published in Optics Express on 20 April 2015 (oe-23-8-10747