“Caracterización de los sistemas de producción de ovinos de pelo en el suroeste del departamento de Matagalpa 2010”

Con el objetivo de caracterizar los sistemas de producción de ovinos de pelo en el territorio suroeste del departamento de Matagalpa 2010. (Sébaco, Ciudad Darío, San Isidro y Matagalpa). Se aplicó una encuesta a 103 productores que poseen ovinos de pelo, la muestra se definió aleatoriamente utilizando la ecuación planteada por Scheaffer (1987), se utilizó la técnica de muestreo de bola de nieve, planteada por Frey et al (2000). Esta investigación permitió conocer las debilidades y oportunidades en los sistemas de explotación de esta especie promisoria para la zona seca del país. Con los resultados obtenidos de las encuestas se procedió ha elaborar una base de datos en el programa SPSS versión 11.5 en español. Encontrando un predominio del sexo femenino como titulares de las explotaciones ovinas, 58.3% cursó educación primaria, el 98% de las explotaciones cuentan con raza pelibuey, el 100% de las explotaciones realizan destete y monta de forma natural, una media de mortalidad de corderos de 1, alimentan a las ovejas con potrero sin división (81.6%), se suministra pasto de corte, pastoreo, leguminosas y se suplementa sal común 49.5%, aplican vacunas contra ántrax y pierna negra (63.1%), desparasitaciones internas y externas (66%), ambos con una frecuencia de 2 veces al año, en el manejo productivo no se lleva control en la actividad ovina (100%), los equipo e instalaciones son rústicas, los corrales ovinos el son elaborados con alambre y/o madera, techado con plástico y/o zinc (49.51%), en cuanto a asistencia técnica el 58.3% ha recibid

MOF-74 as an Efficient Catalyst for the Low-Temperature Selective Catalytic Reduction of NO_<i>x</i> with NH₃

In this work, Mn-MOF-74 with hollow spherical structure and Co-MOF-74 with petal-like shape have been prepared successfully via the hydrothermal method. The catalysts were characterized using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermogravimetry–mass spectrum analysis (TG-MS), N₂ adsorption/desorption, scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). It is found that MOF-74­(Mn, Co) exhibits the capability for selective catalytic reduction (SCR) of NO_<i>x</i> at low temperatures. Both experimental (temperature-programmed desorption, TPD) and computational methods have shown that Co-MOF-74 and Mn-MOF-74 owned high adsorption and activation abilities for NO and NH₃. The catalytic activities of Mn-MOF-74 and Co-MOF-74 for low-temperature denitrification (deNO_<i>x</i>) in the presence of NH₃ were 99% at 220 °C and 70% at 210 °C, respectively. It is found that the coordinatively unsaturated metal sites (CUSs) in M-MOF-74 (M = Mn and Co) played important roles in SCR reaction. M-MOF-74 (M = Mn and Co), especially Mn-MOF-74, showed excellent catalytic performance for low-temperature SCR. In addition, in the reaction process, NO conversion on Mn-MOF-74 decreased with the introduction of H₂O and SO₂ and almost recovered when gas was cut off. However, for Co-MOF-74, SO₂ almost has no effect on the catalytic activity. This work showed that MOF-74 could be used prospectively as deNO_<i>x</i> catalyst

DataSheet_1_Nasal and cutaneous mucormycosis in two patients with lymphoma after chemotherapy and target therapy: Early detection by metagenomic next-generation sequencing.xls

Mucormycosis is a conditionally pathogenic fungal disease with high morbidity that mainly affects patients with decreased immunity. Diagnosis relies on the histopathological examination of microorganisms with the typical structure of mucormycetes in tissues and subsequent confirmation via culture. Early detection of causative microorganisms is critical to rapidly administer appropriately targeted antibiotics. Metagenomic next-generation sequencing (mNGS) is an innovative and sensitive technique used to identify pathogenic strains. Here we used mNGS to timely diagnose an infection with Lichtheimia ramosa and Mucor irregularis in two patients with hematologic malignancies; the infections manifested as nasal and cutaneous infections and developed after chemotherapy and small molecule targeted therapy. Following treatment with amphotericin B cholesteryl sulfate complex, the symptoms were reduced significantly, and both patients obtained successful outcomes. Additionally, we searched and summarized the current medical literature on the successful diagnosis of mucormycosis using mNGS. These cases indicated that mNGS, a novel culture-independent method, is capable of rapid, sensitive, and accurate identification of pathogens. mNGS may be a complementary method for the early identification of mucormycosis, allowing for appropriate and timely antibiotic administration and thus improving patient outcomes.</p

DataSheet_3_Nasal and cutaneous mucormycosis in two patients with lymphoma after chemotherapy and target therapy: Early detection by metagenomic next-generation sequencing.xlsx

Mucormycosis is a conditionally pathogenic fungal disease with high morbidity that mainly affects patients with decreased immunity. Diagnosis relies on the histopathological examination of microorganisms with the typical structure of mucormycetes in tissues and subsequent confirmation via culture. Early detection of causative microorganisms is critical to rapidly administer appropriately targeted antibiotics. Metagenomic next-generation sequencing (mNGS) is an innovative and sensitive technique used to identify pathogenic strains. Here we used mNGS to timely diagnose an infection with Lichtheimia ramosa and Mucor irregularis in two patients with hematologic malignancies; the infections manifested as nasal and cutaneous infections and developed after chemotherapy and small molecule targeted therapy. Following treatment with amphotericin B cholesteryl sulfate complex, the symptoms were reduced significantly, and both patients obtained successful outcomes. Additionally, we searched and summarized the current medical literature on the successful diagnosis of mucormycosis using mNGS. These cases indicated that mNGS, a novel culture-independent method, is capable of rapid, sensitive, and accurate identification of pathogens. mNGS may be a complementary method for the early identification of mucormycosis, allowing for appropriate and timely antibiotic administration and thus improving patient outcomes.</p

DataSheet_2_Nasal and cutaneous mucormycosis in two patients with lymphoma after chemotherapy and target therapy: Early detection by metagenomic next-generation sequencing.xls

Mucormycosis is a conditionally pathogenic fungal disease with high morbidity that mainly affects patients with decreased immunity. Diagnosis relies on the histopathological examination of microorganisms with the typical structure of mucormycetes in tissues and subsequent confirmation via culture. Early detection of causative microorganisms is critical to rapidly administer appropriately targeted antibiotics. Metagenomic next-generation sequencing (mNGS) is an innovative and sensitive technique used to identify pathogenic strains. Here we used mNGS to timely diagnose an infection with Lichtheimia ramosa and Mucor irregularis in two patients with hematologic malignancies; the infections manifested as nasal and cutaneous infections and developed after chemotherapy and small molecule targeted therapy. Following treatment with amphotericin B cholesteryl sulfate complex, the symptoms were reduced significantly, and both patients obtained successful outcomes. Additionally, we searched and summarized the current medical literature on the successful diagnosis of mucormycosis using mNGS. These cases indicated that mNGS, a novel culture-independent method, is capable of rapid, sensitive, and accurate identification of pathogens. mNGS may be a complementary method for the early identification of mucormycosis, allowing for appropriate and timely antibiotic administration and thus improving patient outcomes.</p

DataSheet_4_Nasal and cutaneous mucormycosis in two patients with lymphoma after chemotherapy and target therapy: Early detection by metagenomic next-generation sequencing.xlsx

Mucormycosis is a conditionally pathogenic fungal disease with high morbidity that mainly affects patients with decreased immunity. Diagnosis relies on the histopathological examination of microorganisms with the typical structure of mucormycetes in tissues and subsequent confirmation via culture. Early detection of causative microorganisms is critical to rapidly administer appropriately targeted antibiotics. Metagenomic next-generation sequencing (mNGS) is an innovative and sensitive technique used to identify pathogenic strains. Here we used mNGS to timely diagnose an infection with Lichtheimia ramosa and Mucor irregularis in two patients with hematologic malignancies; the infections manifested as nasal and cutaneous infections and developed after chemotherapy and small molecule targeted therapy. Following treatment with amphotericin B cholesteryl sulfate complex, the symptoms were reduced significantly, and both patients obtained successful outcomes. Additionally, we searched and summarized the current medical literature on the successful diagnosis of mucormycosis using mNGS. These cases indicated that mNGS, a novel culture-independent method, is capable of rapid, sensitive, and accurate identification of pathogens. mNGS may be a complementary method for the early identification of mucormycosis, allowing for appropriate and timely antibiotic administration and thus improving patient outcomes.</p

Transfer Charge and Energy of Ag@CdSe QDs-rGO Core–Shell Plasmonic Photocatalyst for Enhanced Visible Light Photocatalytic Activity

Plasmonic heteronanostructures in semiconductor type display extraordinary photocatalytic efficiency induced by the plasmonic energy that operates in the Ag@CdSe-rGO hybrid ternary composites. The obtained plasmonic photocatalysts in nanoscale were fabricated by using a one-step hydrothermal method, during which the in situ nucleation of Ag@CdSe core–shell nanoparticles and the reduction of GO to rGO occurred simultaneously. Three different roles of Ag core and the junction of synergistic properties arising from the introduced rGO jointly enhanced the optical properties of CdSe. Localized plasmon resonance (LPR) effects of plasmonic Ag contribute to the separation of photogenerated e^–/h⁺ pairs via the electrons and resonant energy transfer. Electrochemical investigations have further confirmed the enhanced separation of the photogenerated e^–/h⁺ pairs. From comparative photocatalytic experiments of Ag@CdSe-rGO and Ag/CdSe-rGO, the plasmonic effect of the Ag core in the Ag@CdSe-rGO nanostructure serves to prolong the charge separation under visible light beyond common attached trimers

Cumulative meta-analysis of the association between GSTM1 null genotype and lung cancer susceptibility.

<p>(a) publication time cumulative meta-analysis of GSTM1 variants and lung cancer risk; (b) sample size cumulative meta-analysis of GSTM1 variants and lung cancer risk.</p

Cumulative meta-analysis of the association between <i>GSTT1</i>/<i>GSTM1-GSTT1</i> genetic polymorphisms and lung cancer susceptibility.

<p>(a) publication time cumulative meta-analysis of <i>GSTT1</i> variants and lung cancer risk; (b) sample size cumulative meta-analysis of <i>GSTT1</i> variants and lung cancer risk; (c) publication time cumulative meta-analysis of <i>GSTM1-GSTT1</i> variants and lung cancer risk; (d) sample size cumulative meta-analysis of <i>GSTM1-GSTT1</i> variants and lung cancer risk.</p

Begg's funnel plot and Egger's linear regression test of the association between <i>GSTs</i> polymorphisms and lung cancer risk.

<p>Begg's funnel plot is used to detect potential publication bias in which a symmetric funnel shape means no publication bias. Egger's linear regression test is used to quantify the potential presence of publication bias; (a) (b) <i>GSTM1</i>: No publication bias has been found from 68 inclusive studies about the association between <i>GSTM1</i> polymorphisms and lung cancer risk by Begg's??? test and Egger's test, respectively; (c)(d) <i>GSTT1</i>: No publication bias has been found from 17 inclusive studies about the association between <i>GSTT1</i> polymorphisms and lung cancer risk by Begg's test and Egger's test, respectively; (e)(f) <i>GSTM1-GSTT1</i> dual-null genotype: No publication bias has been found from 8 inclusive studies about the association between <i>GSTM1-GSTT1</i> dual-null genotype and lung cancer risk by Begg's test and Egger's test, respectively.</p