65 research outputs found

    Total Saponins of Aralia Elata (Miq) Seem Alleviate Calcium Homeostasis Imbalance and Endoplasmic Reticulum Stress-Related Apoptosis Induced by Myocardial Ischemia/Reperfusion Injury

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    Background/Aims: Total saponins of Aralia elata (Miq) Seem (AS) from the Chinese traditional herb Long ya Aralia chinensis L. reportedly provide cardioprotective effects, but the exact mechanisms require further study. Previous studies have showed that myocardial ischemia/ reperfusion injury (MIRI) was related to calcium homeostasis imbalance and endoplasmic reticulum stress (ERS). Thus, this study aimed to demonstrate protective effects of AS on MIRI. Methods: After administrating AS for 5 days, the left anterior descending artery coronary artery of Sprague-Dawley (SD) rats was ligated for 30 min. After 48 h of reperfusion, haemodynamics, Evans blue/ 2,3,5-triphenyltetrazolium chloride (TTC) staining, hematoxylin-eosin (HE) staining, masson staining and the levels of lactate dehydrogenase (LDH) and creatine kinase (CK), superoxide dismutase (SOD), malondialdehyde (MDA) were detected to assess MIRI. ATPase activity and Western Blot were used to study the mechanisms. Results: Compared with IR group, AS treatment groups could significantly reduce myocardial infarct size; improve myocardial pathologic progress; decrease content of LDH, CK, and MDA; increase content of SOD; and restore the activities of Ca2+-Mg2+-ATPase, Na+-K+-ATPase, sarcoplasmic reticulum Ca2+-ATPases (SERCA), and calcineurin (CaN). AS treatment groups also significantly up-regulated the expression of GRP78, C/EBP homologous protein (CHOP), and Bax, and down-regulated the expression of Bcl-2, all similar to the effects of ERS. Conclusion: These findings illustrated that AS could prevent myocardial ischemia/reperfusion injury and reduce calcium homeostasis imbalance and ERS-related apoptosis

    Observation of a C-type short-range antiferromagnetic order in layer spacing expanded FeS.

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    We report neutron diffraction studies of FeS single crystals obtained from Rb x Fe2-y S2 single crystals via a hydrothermal method. While no 5×5 iron vacancy order or block antiferromagnetic order typical of Rb x Fe2-y S2 is found in our samples, we observe C-type short-range antiferromagnetic order with moments pointed along the c axis hosted by a different phase of FeS with an expanded interlayer spacing. The Néel temperature for this magnetic order is determined to be 170 ± 4 K. Our finding of a variant FeS structure hosting this C-type antiferromagnetic order demonstrates that the known FeS phase synthesized in this method is in the vicinity of a magnetically ordered ground state, providing insights into understanding a variety of phenomena observed in FeS and the related FeSe1-x S x iron chalcogenide system

    Hydrothermally Grown ZnO Micro/Nanotube Arrays and Their Properties

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    We reported the optical and wettability properties of aligned zinc oxide micro/nanotube arrays, which were synthesized on zinc foil via a simple hydrothermal method. As-synthesized ZnO micro/nanotubes have uniform growth directions along the [0001] orientations with diameters in the range of 100–700 nm. These micro/nanotubes showed a strong emission peak at 387 nm and two weak emission peaks at 422 and 485 nm, respectively, and have the hydrophobic properties with a contact angle of 121°. Single ZnO micro/nanotube-based field-effect transistor was also fabricated, which shows typical n-type semiconducting behavior

    The Distribution of Benefits for Players in Agricultural Industrial Chain

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    Players of the agricultural industrial chain pursue their own profit maximization, which can lead to conflicts of interest and affect the stability of the industrial chain. Therefore, fair and reasonable profit allocation mechanism is the key to guaranteeing the development and strengthening the strategic alliance relationship between participate members. Shapley model is an effective method to solve the profit distribution in cooperative relations. But it does not consider the three factors: risks faced by players during the operation of the agricultural industrial chain, technology innovation ability, and the degree of participating in the cooperation. So, correction factors are introduced to modify the Shapley value model, in order to make the distribution of benefits more equitable and reasonable, and effectively guide practice

    Carbon emission area division of power system considering carbon

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    With the advancement of China’s “carbon neutrality” process, the carbon emission quotas of various types of users have gradually tightened, “carbon responsibility” has attracted widespread attention, and the “high/low carbon area” is divided from the perspective of the user side, and the analysis of “carbon responsibility” is conducive to building a flexible and reasonable response mechanism that promotes carbon reduction demand, and revitalizes the carbon reduction potential of the user side. Based on the theory of carbon emission flow, considering the generator output power transfer distribution factor, The emergence of the proportional sharing principle and electrical dissection theory solves the problem of load-side electricity consumption sources. The emerging carbon emission stream theory, which is both applicable to power systems and consistent with the proportional sharing principle, is used as a basis to further delineate high/low carbon areas. By tracing from the load side to the power side, we can determine the power consumption attributes of the load side, differentiate between high-carbon and low-carbon power users, divide the typical areas of high-carbon and low-carbon power, the levy carbon tax on high-carbon power, change the power consumption habits of the load side to achieve effective demand response, and complete the low-carbon planning of the power system from the load side. the carbon emission flow distribution factor model is established, a method of dividing the high and low carbon area of the power system is proposed, and the effectiveness of the proposed method is verified by the IEEE30 node system
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