3,410 research outputs found
Soil respiration patterns and controls in limestone cedar glades
Aims
Drivers of soil respiration (R s ) in rock outcrop ecosystems remain poorly understood. We investigated these drivers in limestone cedar glades, known for their concentrations of endemic plant species and for seasonal hydrologic extremes (xeric and saturated conditions), and compared our findings to those in temperate grasslands and semi-arid ecosystems. Methods
We measured R s , soil temperature (T s ), volumetric soil water content (SWC), soil organic matter (SOM), soil depth, and vegetation cover monthly over 16 mo and analyzed effects of these variables on R s . Results
Seasonally, R s primarily tracked T s (r2 = 0.77; P \u3c 0.01), however R s was depressed during a summer drought. SOM was highly variable spatially, and incorporating SOM effects into the R s model dramatically improved model performance. Both shallow soil and sparse vegetation cover were also associated with lower R s . Conclusions
Soil depth, SOM, and vegetation cover were important drivers of R s in limestone cedar glades. Seasonal R s patterns reflected those for mesic temperate grasslands more than for semi-arid ecosystems, in that R s primarily tracked temperature for most of the year
Immigrant Entrepreneurs Creating Jobs and Strengthening the U.S. Economy in Growing Industries
The focus of this report evolved from a 2010 conference at Babson College on "Immigrant Entrepreneurship in Massachusetts" sponsored by The Immigrant Learning Center, Inc. (ILC) from which two key ideas emerged. One is that there is an "immigrant entrepreneurship ecology" that includes immigrant neighborhood storefront businesses; immigrant high-tech and health science entrepreneurs; immigrant non-tech growth businesses; and immigrant transnational businesses. A second idea was that these growing, non-tech industries (including transportation, food and building services) have not attracted much attention. Interestingly, these sectors can be crucial to the expansion of the green economy. Within this context, The ILC decided to look at these three sectors in Massachusetts as well as in New York and Pennsylvania.Moreover, the report dramatically illustrates how immigrant entrepreneurs look for niches in underserved markets. For example, vans and other alternatives to mass transit serve unmet transportation needs in urban areas. Food intended to be a "taste of home" for compatriots in local restaurants and grocery stores becomes popular and influences the eating habits of other Americans. Workers who enter industries like landscaping or cleaning because they don't require much English gain experience and see opportunities to start their own companies. Businesses like these add value to American life by expanding the economy rather than taking away from native businesses
Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection
Salvianolic acids are the most abundant water-soluble compounds extracted from Radix Salvia miltiorrhiza (Danshen). In China, Danshen has been wildly used to treat cardiovascular diseases for hundreds of years. Salvianolic acids, especially salvianolic acid A (Sal A) and salvianolic acid B (Sal B), have been found to have potent anti-oxidative capabilities due to their polyphenolic structure. Recently, intracellular signaling pathways regulated by salvianolic acids in vascular endothelial cells, aortic smooth muscle cells, as well as cardiomyocytes, have been investigated both in vitro and in vivo upon various cardiovascular insults. It is discovered that the cardiovascular protection of salvianolic acids is not only because salvianolic acids act as reactive oxygen species scavengers, but also due to the reduction of leukocyte-endothelial adherence, inhibition of inflammation and metalloproteinases expression from aortic smooth muscle cells, and indirect regulation of immune function. Competitive binding of salvianolic acids to target proteins to interrupt protein-protein interactions has also been found to be a mechanism of cardiovascular protection by salvianolic acids. In this article, we review a variety of studies focusing on the above mentioned mechanisms. Besides, the target proteins of salvianolic acids are also described. These results of recent advances have shed new light to the development of novel therapeutic strategies for salvianolic acids to treat cardiovascular diseases
Methods For Estimating Sediment Yield And Dam Capacity In The Great Lakes Watershed
Sedimentation is the most important factor in the longevity of dams built in the United States. As most dams are reaching their capacity for sediment storage, this study investigated the historical and predicted future rates of sediment accumulation as well as the remaining storage capacity. This study examined the mechanisms influencing sediment production and storage in the watershed to provide future insight regarding potential control of this process. Twelve reservoirs throughout the Great Lakes watershed were selected and analyzed for their greater applicability to the entire watershed. Both historic and new data were collected on these dams to determine how the storage capacity has changed over time and to forecast the remaining life-span of the impoundments. Different methods were used to estimate the sediment yield and dam capacity including (1) bathymetric subtraction, (2) USGS (United States Geological Survey) sediment gages, and (3) radionuclide dating. Some correlation was found between agricultural watersheds and a higher sediment load per square mile than forested watersheds do
Antiferromagnetic and Orbital Ordering on a Diamond Lattice Near Quantum Criticality
We present neutron scattering measurements on powder samples of the spinel
FeSc2S4 that reveal a previously unobserved magnetic ordering transition
occurring at 11.8(2)~K. Magnetic ordering occurs subsequent to a subtle
cubic-to-tetragonal structural transition which distorts Fe coordinating sulfur
tetrahedra lifting the orbital degeneracy. The application of 1~GPa hydrostatic
pressure appears to destabilize this N\'eel state, reducing the transition
temperature to 8.6(8)~K and redistributing magnetic spectral weight to higher
energies. The relative magnitudes of ordered
and fluctuating moments show that the
magnetically ordered ground state of FeSc2S4 is drastically renormalized and in
proximity to criticality.Comment: 16 pages, 12 figure
Multi-Omics Analyses Detail Metabolic Reprogramming in Lipids, Carnitines, and Use of Glycolytic Intermediates between Prostate Small Cell Neuroendocrine Carcinoma and Prostate Adenocarcinoma.
As the most common cancer in men, prostate cancer is molecularly heterogeneous. Contributing to this heterogeneity are the poorly understood metabolic adaptations of the two main types of prostate cancer, i.e., adenocarcinoma and small cell neuroendocrine carcinoma (SCNC), the latter being more aggressive and lethal. Using transcriptomics, untargeted metabolomics and lipidomics profiling on LASCPC-01 (prostate SCNC) and LNCAP (prostate adenocarcinoma) cell lines, we found significant differences in the cellular phenotypes of the two cell lines. Gene set enrichment analysis on the transcriptomics data showed 62 gene sets were upregulated in LASCPC-01, while 112 gene sets were upregulated in LNCAP. ChemRICH analysis on metabolomics and lipidomics data revealed a total of 25 metabolite clusters were significantly different. LASCPC-01 exhibited a higher glycolytic activity and lower levels of triglycerides, while the LNCAP cell line showed increases in one-carbon metabolism as an exit route of glycolytic intermediates and a decrease in carnitine, a mitochondrial lipid transporter. Our findings pinpoint differences in prostate neuroendocrine carcinoma versus prostate adenocarcinoma that could lead to new therapeutic targets in each type
A Methodology for Cell Merging Circuit Transformation on Post-placement High Speed Design
This paper proposes a localize circuit transformation algorithm to further optimize the post-placement netlist in order to improve the overall timing of a design. The proposed algorithm reduces the total cell delay and net delay of timing violation paths by replacing a small group of cells (form up by two to three cells) that are placed close to each other with a functional equivalent standard cell available in the technology library. The algorithm has been implemented and applied to a number of optimized postplacement netlists which have went through conventional post-placement circuit transformation optimization processes such as gate relocation, cell re-sizing, repeater insertion and cell replication. The experimental results show that on average, this algorithm is able to further improve the timing of the optimized post-placement netlist by 27.75%, while keeping the design area increase by 0.2%
Remote Sensing of Environmental Changes in Cold Regions
This Special Issue gathers papers reporting recent advances in the remote sensing of cold regions. It includes contributions presenting improvements in modeling microwave emissions from snow, assessment of satellite-based sea ice concentration products, satellite monitoring of ice jam and glacier lake outburst floods, satellite mapping of snow depth and soil freeze/thaw states, near-nadir interferometric imaging of surface water bodies, and remote sensing-based assessment of high arctic lake environment and vegetation recovery from wildfire disturbances in Alaska. A comprehensive review is presented to summarize the achievements, challenges, and opportunities of cold land remote sensing
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Isomeric triazines exhibit unique profiles of bioorthogonal reactivity.
Expanding the scope of bioorthogonal reactivity requires access to new and mutually compatible reagents. We report here that 1,2,4-triazines can be tuned to exhibit unique reaction profiles with biocompatible strained alkenes and alkynes. Computational analyses were used to identify candidate orthogonal reactions, and the predictions were experimentally verified. Notably, 5-substituted triazines, unlike their 6-substituted counterparts, undergo rapid [4 + 2] cycloadditions with a sterically encumbered strained alkyne. This unique, sterically controlled reactivity was exploited for dual bioorthogonal labeling. Mutually orthogonal triazines and cycloaddition chemistries will enable new multi-component imaging applications
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