Detecting Stress and Fatigue Cracks

Discoveries in using open ended rectangular waveguides for microwave surface crack detection and sizing have generated interest. The foundation, potential, advantages and disadvantages of this methodology, developed at the Applied Microwave Nondestructive Testing Laboratory in the Electrical Engineering Department at Colorado State University, are discussed. Microwave techniques in general and this particular approach offer certain unique advantages that can advance the state of the art of fatigue/surface crack detection. The basic features and capabilities of this technique have been theoretically and experimentally investigated these past few years. However, more developmental work is needed to bring this technique from the laboratory to the real testing environment. The microwave method described has proven to be very effective in detecting and characterizing surface cracks in metals. It is inexpensive and can readily be applied in various environments. This approach applies to exposed, empty, filled and covered cracks. Cracks may also be detected remotely (i.e. the use on a liftoff in between the waveguide aperture and the surface under examination)

SWEEPFINDER2: Increased sensitivity, robustness, and flexibility

SweepFinder is a popular program that implements a powerful likelihood-based method for detecting recent positive selection, or selective sweeps. Here, we present SweepFinder2, an extension of SweepFinder with increased sensitivity and robustness to the confounding effects of mutation rate variation and background selection, as well as increased flexibility that enables the user to examine genomic regions in greater detail and to specify a fixed distance between test sites. Moreover, SweepFinder2 enables the use of invariant sites for sweep detection, increasing both its power and precision relative to SweepFinder

Effect of Growth Hormone (hGH) Replacement Therapy on Physical Work Capacity and Cardiac and Pulmonary Function in Patients with hGH Deficiency Acquired in Adulthood.

The effects of 6 months of replacement therapy with recombinant human GH (hGH) on physical work capacity and cardiac structure and function were investigated in 20 patients with hGH deficiency of adult onset in a double blind, placebo-controlled trial. The GH dose of 12.5 micrograms/kg BW was self-administered daily sc. Oxygen consumption (VO2), CO2 production, and ventilatory volumes were measured during exercise on a bicycle spiroergometer. M-Mode echocardiography was performed using standard techniques. The VO2 max data, expressed per kg BW (mL/min.kg BW) showed a significant increase from 23.2 +/- 2.4 to 30.0 +/- 2.3 (P < 0.01) in the hGH-treated group, whereas the VO2 max data, expressed per lean body mass (milliliters per min/kg lean body mass) did not change significantly in either group. Maximal O2 pulse (milliliters per beat) increased significantly from 15.2 +/- 5.6 to 19.6 +/- 3.3 mL/beat (P < 0.01), but remained constant in the placebo group. The maximal power output (watts +/- SE) increased significantly (P < 0.01) from 192.5 +/- 13.5 to 227.5 +/- 11.5 in the hGH-treated group, but remained constant in the placebo group. Cardiac structure (left ventricular posterior wall, interventricular septum thickness, left ventricular mass, left ventricular end-systolic dimension, and left ventricular end-diastolic dimension) as well as echocardiographically assessed cardiac function did not change significantly after 6 months of treatment in either group. We conclude that hGH replacement in hGH-deficient adults improves oxygen uptake and exercise capacity. These improvements in pulmonary parameters might be due to an increase in respiratory muscle strength and partly to the changes in muscle volume per se observed during hGH replacement therapy. Furthermore, an increased cardiac output might contribute to the improvement in exercise performance during hGH treatment. According to our data, hGH replacement therapy leads to an improvement of exercise capacity and maximal oxygen uptake, but has no significant effect on cardiac structure

Electrical conductance of molecular junctions by a robust statistical analysis

We propose an objective and robust method to extract the electrical conductance of single molecules connected to metal electrodes from a set of measured conductance data. Our method roots in the physics of tunneling and is tested on octanedithiol using mechanically controllable break junctions. The single molecule conductance values can be deduced without the need for data selection.Comment: 4 figure

Measurement Parameter Optimization for Surface Crack Detection in Metals using an Open-Ended Waveguide Probe

Fatigue and stress induced surface crack detection in metals is an important practical issue. A newly developed microwave inspection approach, using an open-ended rectangular waveguide, has proved to be an effective tool for detecting such cracks. This novel microwave approach overcomes some of the limitations associated with the standard detection methods for surface crack detection. In addition, this approach is applicable to exposed, filled (with a dielectric such as dirt, rust, etc.) and cracks under dielectric coatings such as paint. This paper presents the basic foundation of this surface crack detection methodology along with the ways by which measurement parameters may be optimized for increased detection sensitivity

Analysis of the Crack Characteristic Signal using a Generalized Scattering Matrix Representation

Electromagnetic properties of a system formed by an open-ended rectangular waveguide and a surface crack/slot in a metallic specimen are described in this paper. Scanning a crack on a metal surface changes the reflection coefficient of the incident dominant mode. A model as a function of relative crack location within the waveguide aperture (i.e., crack moving with respect to the waveguide aperture) is desired to describe and optimize practical crack detection applications. Hence, the change in the reflection coefficient for a generalized system encompassing empty, filled, and finite cracks located at an arbitrary position inside the waveguide aperture, is evaluated. A moment solution approach is employed, and a magnetic current density M is introduced over the common aperture formed by the waveguide and the crack. Subsequently, the junction formed by the waveguide and the cracked metallic surface is separated into two systems. A numerical solution employing the method of moments is obtained, and the reflection coefficient at the waveguide aperture is expressed in terms of the generalized scattering matrix. The convergence behavior is studied to determine an optimized set of basis functions and the optimal number of higher order modes for a fast and accurate solution. Numerical results presented in this paper include the evaluation of the field distribution over the waveguide aperture. Finally, the theoretical and measured crack characteristic signals are compared

Modeling of Surface Hairline-Crack Detection in Metals under Coatings using an Open-Ended Rectangular Waveguide

A surface-breaking hairline crack or a narrow slot in a metallic specimen when scanned by an open-ended rectangular waveguide probe influences the reflection-coefficient properties of the incident dominant mode. Subsequent recording of a change in the standing-wave pattern while scanning such a surface results in what is known as the crack characteristic signal. Since microwave signals penetrate inside dielectric materials, this methodology is capable of detecting cracks under dielectric coatings of various electrical thicknesses as well. To electromagnetically model the interaction of an open-ended rectangular waveguide with a surface-breaking hairline crack under a dielectric coating, the dielectric-coating layer is modeled as a waveguide with a large cross section. Thus, the problem is reduced to a system of three waveguides interacting with each other while the location of the crack is continuously changing relative to the probing waveguide aperture (a dynamic scanning problem). An analysis of modeling the dielectric-coating layer as a dielectric-filled waveguide with a large cross section is given, and its comparison with radiation into an unbounded medium is presented. For obtaining the reflection coefficients of the dominant and higher order modes, the electromagnetic properties of the probing waveguide-dielectriccoating layer junction and the dielectric-coating layer-crack junction are separately analyzed. For each junction, a magneticcurrent density M is introduced over the common aperture. Subsequently, the junction formed by the two respective waveguide sections is separated into two systems. A numerical solution employing the method of moments is obtained, and the properties of the junctions are expressed by their respective generalized scattering matrices. Consequently, the generalized scattering matrix for the total system can be evaluated. The convergence behavior of the system is studied to determine an optimal set of basis functions and the optimal number of higher order modes for a fast and accurate solution. Finally, the theoretical and measured crack characteristic signals are compared

Influence of static electric fields on an optical ion trap

We recently reported on a proof-of-principle experiment demonstrating optical trapping of an ion in a single-beam dipole trap superimposed by a static electric potential [Nat. Photonics 4, 772--775 (2010)]. Here, we first discuss the experimental procedures focussing on the influence and consequences of the static electric potential. These potentials can easily prevent successful optical trapping, if their configuration is not chosen carefully. Afterwards, we analyse the dipole trap experiments with different analytic models, in which different approximations are applied. According to these models the experimental results agree with recoil heating as the relevant heating effect. In addition, a Monte-Carlo simulation has been developed to refine the analysis. It reveals a large impact of the static electric potential on the dipole trap experiments in general. While it supports the results of the analytic models for the parameters used in the experiments, the analytic models cease their validity for significantly different parameters. Finally, we propose technical improvements for future realizations of experiments with optically trapped ions.Comment: 16 pages, 16 figure