A memória da luz : customizações e encontros com o espectador

Tese (doutorado)—Universidade de Brasília, Instituto de Artes, Departamento de Artes Visuais, 2017.O presente trabalho fala do desenvolvimento e aplicação de simulacros computacionais da luz como opção poética que é estética e empiricamente investigada de modo a envolver a comparação de minhas percepções e meus horizontes, como artista, com os de meus espectadores, como forma de encontrar aproximações e distâncias entre essas percepções e horizontes enquanto criações necessariamente implicadas na fruição esteticamente qualificada desses simulacros, em favor de um maior entendimento sobre o que poderia ser um encontro ou comunicação possível entre autor e receptor e na expectativa de obter, pelo somatório de percepções e horizontes colhidos desses espectadores, uma revelação paulatina das propostas artísticas correspondentes a esses simulacros.This work is about the development and application of computer light simulacra as poetic option that is aesthetically and empirically investigated in a way that involves the comparison of my perceptions and horizons, as an artist, with those of my spectators, as a way to find the proximities and distances between those perceptions and horizons as creations necessarily implied in the fruition aesthetically qualified of these simulacra, in favor of a greater understanding of what could be a possible encounter or communication between author and receiver and in the expectation of a gradual revelation of the artistic proposals corresponding to these simulacra, by the sum of perceptions and horizons taken from those spectators

The complete mitochondrial genome and phylogenetic analysis of <i>Polythlipta liquidalis</i> Leech, 1889 (Crambidae: spilomelinae)

The complete mitochondrial genome of Polythlipta liquidalis Leech, 1889 was sequenced and annotated in this study, which was the first reported complete mitogenome of the genus Polythlipta. The mitogenome of P. liquidalis is 15,305 bp in length and was predicted to encode 37 typical mitochondrial genes including 13 protein-coding genes (PCGs), 22 transfer RNA genes (tRNAs), 2 ribosomal RNA genes (rRNAs), and one major non-coding A-T rich region. The maximum likelihood phylogenetic analysis based on the 13 PCGs was constructed, including P. liquidalis and 15 related Spilomelinae species, using Ostrinia furnacalis as the outgroup. The result showed that P. liquidalis is grouped with Sinomphisa plagialis. These data will serve as a molecular resource for species identification of P. liquidalis and become a valuable resource for a range of genetic, functional, evolutionary and comparative genomic studies on members of Spilomelinae.</p

DataSheet1_An improved approach for the continuous retardation spectra of concrete creep and applications.docx

Creep is an important physical property of concrete and can lead to additional displacement, stress redistribution, and even cracking in concrete structures, inducing prestress loss of large-scale prestressed concrete structures. When an exponential algorithm is used to calculate the long-term creep of concrete, it is usually necessary to apply the continuous retardation spectra of the material. In the improved approach proposed here, the continuous retardation spectra can be obtained by the Weeks inverse Laplace transform. The CEB MC90 creep model is taken as an example to analyze the computational process, efficiency, and error of the approach. The improved approach is further applied to the ACI 209R-92, JSCE, and GL2000 concrete creep models. Through comparison with other methods, the advantages of the improved approach are illustrated, and some useful conclusions are drawn.</p

DataSheet1_Integrated network pharmacology and metabolomics to reveal the mechanism of QiShenYiQi Dripping Pills against cardiac structural and functional abnormalities.docx

Background: Heart failure (HF), the final stage of cardiovascular diseases, is a clinical syndrome of cardiac structural or functional abnormalities. QiShenYiQi Dripping Pills, short for QSYQ, showed effectiveness and safety in the treatment of HF according to modern pharmacological research and clinical studies, but the mechanism remains unclear. This study aims to clarify the mechanism of QSYQ in treating heart failure through the analysis to critical biomarkers, targets and pathways.Materials and Methods: In this study, the efficacies of QSYQ in non-human primates and rodents were evaluated, and the mechanism was demonstrated by integrating network pharmacology and metabolomics analysis. Furthermore, the targets from network pharmacology and the metabolites from targeted metabolomics were jointly analyzed to screen the critical pathways.Results: In rhesus monkeys with spontaneous chronic heart failure, nasogastric administration of QSYQ for 12 weeks caused profound improvement of systolic and diastolic function as evidenced by echocardiography detection. Consistently, QSYQ administration especially with higher dose lowered the blood pressure and improved the ventricular remodeling, collagen deposition and fibrosis markedly in Spontaneous Hypertension Rats (SHR) model. Computational prediction showed that QSYQ exhibited anti-HF effects possibly through HIF-1 signaling pathway, FoxO signaling pathway, TNF signaling pathway, PI3K-Akt signaling pathway and other enriched paths. Metabolomics analysis obtained 23 significantly altered metabolites, revealing that QSYQ significantly regulated the abnormal levels of fatty acids, carnitines, organic acids pyridines, nucleosides, which were mostly involved in myocardial energy metabolism related pathways.Conclusion: Based on serum and myocardium metabolomics and network pharmacology, the present study revealed that the actions of QSYQ in treating HF depend on multi-components, multi-targets and multi-pathways.</p

Additional file 1: of Biological mechanisms discriminating growth rate and adult body weight phenotypes in two Chinese indigenous chicken breeds

The microarray hybridization data for the breast muscle tissue. The file shows the breast muscle tissue microarray data used for the functional analyses. (XLS 10476 kb

Comparison of insulin-like growth factor-1 (IGF-1) mRNA expression.

<p>IGF-1 mRNA abundance in the liver (a), breast muscles (b) and in thigh muscles (c) from the Daweishan mini chicken and the Wuding chicken breeds, and the commercial Avian broiler hybrid at weeks 0, 4, 8 and 12. Statistical significance of difference among chickens at a specific age is indicated by asterisks (*: P<0.05; **: P<0.01). Statistical significance among different ages within a breed / hybrid is indicated with letters (lower case: P<0.05; capitals: P<0.01).</p

Primer sequences for the target genes and their annealing temperatures.

<p>Primer sequences for the target genes and their annealing temperatures.</p

Comparison of growth hormone binding protein (GHBP) mRNA expression.

<p>GHBP mRNA abundance in the liver (a), breast muscles (b) and in thigh muscles (c) from the Daweishan mini chicken and the Wuding chicken breeds, and the commercial Avian broiler hybrid at weeks 0, 4, 8 and 12. Statistical significance of difference among chickens at a specific age is indicated by asterisks (*: P<0.05; **: P<0.01). Statistical significance among different ages within a breed / hybrid is indicated with letters (lower case: P<0.05; capitals: P<0.01).</p

Comparison of insulin-like growth factor-1 receptor (IGF-1R) mRNA expression.

<p>IGF1R mRNA abundance in the liver (a), breast muscles (b) and in thigh muscles (c) from the Daweishan mini chicken and the Wuding chicken breeds, and the commercial Avian broiler hybrid at week 0, 4, 8 and 12. Statistical significance of difference among chickens at a specific age is indicated by asterisks (*: P<0.05; **: P<0.01). Statistical significance among different ages within a breed / hybrid is indicated with letters (lower case: P<0.05; capitals: P<0.01).</p

Comparison of insulin-like growth factor-1 binding protein 2 (IGFBP2) mRNA Expression.

<p>IGFBP mRNA abundance in the liver (a), breast muscles (b) and in thigh muscles (c) from Daweishan mini chicken and the Wuding chicken breeds, and the commercial Avian broiler hybrid at week 0, 4, 8 and 12. Statistical significance of difference among chickens at a specific age is indicated by asterisks (*: P<0.05; **: P<0.01). Statistical significance among different ages within a breed / hybrid is indicated with letters (lower case: P<0.05; capitals: P<0.01).</p