54,081 research outputs found

    Health state utility data in Cystic Fibrosis: A systematic review

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    Introduction: Cystic fibrosis (CF) is a life-limiting, hereditable condition, with the highest prevalence in Europe. CF treatments have led to improvements in clinical symptoms, disease management and decelerated disease progression. However, little is known about the health state utility (HSU) associated with CF disease states, adverse events, and changes in disease severity. Although HSU data have contributed to existing health economic modelling studies, a lack of such data have been highlighted. This systematic review aims to provide a summary of HSU-related research in CF and highlight related research gaps. Methods: Online searches were performed in six databases and studies in any of the following categories were included: (1) estimation of HSUs in CF; (2) mapping studies between patient-reported outcome measures (PROMs) and HSUs; (3) economic evaluations on the management of CF that report primary HSU data; and (4) any CF clinical trial that reported HSU as an outcome. Results: A total of 17 studies were reviewed, of which 12 provided HSU values for specific CF populations. The remaining five articles provided HSU data that were broken down by CF relevant health states, including lung transplantations, pulmonary exacerbation (PEx) events and forced expiratory volume in 1 s (FEV 1). Conclusion: Current HSU data in CF are limited and there is considerable scope for further research, both in providing HSU values for CF and in investigating methods for HSU elicitation/evaluation in CF populations

    Skill development and the making of the global citizen: an analysis of student experiences with study abroad at Humboldt State University

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    Global citizenship is seen as an emerging necessity as work places are shifting to a more global environment and as challenges we face are becoming more global in nature. This thesis focuses on the creation and nurturing of global citizenship through participation in study abroad programming at Humboldt State University (HSU). Research has shown participation in study abroad has an impact on the participant’s skill development (Farraguia and Sanger 2017) and such skill development can be applied to advancement of global citizenship. This thesis utilizes a mixed methodology to develop a thorough understanding of the level of skills associated with studying abroad for HSU students. Spatial data was examined to determine the extent to which HSU students were studying abroad in the same countries as students across the United States. A survey was sent out to 75 recent HSU study abroad participants and a random sample of 350 HSU students to determine global perspectives. Finally, semi-structured face-to-face interviews were conducted with eight students returning from study abroad programs in order to detail how the skills they developed impacted their lives. Europe was the most popular region for both HSU and US study abroad in the 2017/2018 academic year. Survey data indicated study abroad participation increases identification as a global citizen, and the interviewees commonly referenced food in describing the skills they developed from their study abroad experiences

    Contracted Representation of Yang's Space-Time Algebra and Buniy-Hsu-Zee's Discrete Space-Time

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    Motivated by the recent proposition by Buniy, Hsu and Zee with respect to discrete space-time and finite spatial degrees of freedom of our physical world with a short- and a long-distance scales, lPl_P and L,L, we reconsider the Lorentz-covariant Yang's quantized space-time algebra (YSTA), which is intrinsically equipped with such two kinds of scale parameters, λ\lambda and RR. In accordance with their proposition, we find the so-called contracted representation of YSTA with finite spatial degrees of freedom associated with the ratio R/λR/\lambda, which gives a possibility of the divergence-free noncommutative field theory on YSTA. The canonical commutation relations familiar in the ordinary quantum mechanics appear as the cooperative Inonu-Wigner's contraction limit of YSTA, λ→0\lambda \to 0 and $R \to \infty.

    Check Out the Library, 2016 Fall Issue

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    Issue 4 New Publications from the HSU Press Humboldt Scholars Lab for HSU Research Opens Digital Media Lab Opening New & Improved Math Tutoring Lab Write on the First Floor Students are Talking Unpacking & Exploring White Privilege Relax & Gain Focus at the Brain Booth L4 HSU Creates Campus Connectionshttps://digitalcommons.humboldt.edu/library_pub/1010/thumbnail.jp

    Check Out the Library, 2017 Spring Issue

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    Issue 5 Updates from the Academic Technology Team HSU Authors Celebration ideaFest ideaFest Journal News from HSU Press A New Future for Humboldt’s Past 360 Degrees of Innovationhttps://digitalcommons.humboldt.edu/library_pub/1009/thumbnail.jp

    High Density Effective Theory Confronts the Fermi Liquid

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    The high density effective theory recently introduced by Hong and Hsu to describe ultradense relativistic fermionic matter is used to calculate the tree-level forward scattering amplitude between two particles at the Fermi surface. While the direct term correctly reproduces that of the underlying gauge theory, the exchange term has the wrong sign. The physical consequences are discussed in the context of Landau's theoretical description of the Fermi liquid.Comment: 15 pages, 2 figures; conclusion expanded, reference adde

    Connectivity of consecutive-d digraphs

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    AbstractThe concept of consecutive-d digraph is proposed by Du, Hsu and Hwang. It generalizes the class of de Bruijin digraphs, the class of Imase-Itoh digraphs and the class of generalized de Bruijin graphs. We modify consecutive-d digraphs by connecting nodes with a loop into a circuit and deleting all loops. The result in this paper shows that the link-connectivity or the connectivity of modified consecutive-d digraphs get better
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