Health state utility data in Cystic Fibrosis: A systematic review

Introduction: Cystic fibrosis (CF) is a life-limiting, hereditable condition, with the highest prevalence in Europe. CF treatments have led to improvements in clinical symptoms, disease management and decelerated disease progression. However, little is known about the health state utility (HSU) associated with CF disease states, adverse events, and changes in disease severity. Although HSU data have contributed to existing health economic modelling studies, a lack of such data have been highlighted. This systematic review aims to provide a summary of HSU-related research in CF and highlight related research gaps. Methods: Online searches were performed in six databases and studies in any of the following categories were included: (1) estimation of HSUs in CF; (2) mapping studies between patient-reported outcome measures (PROMs) and HSUs; (3) economic evaluations on the management of CF that report primary HSU data; and (4) any CF clinical trial that reported HSU as an outcome. Results: A total of 17 studies were reviewed, of which 12 provided HSU values for specific CF populations. The remaining five articles provided HSU data that were broken down by CF relevant health states, including lung transplantations, pulmonary exacerbation (PEx) events and forced expiratory volume in 1 s (FEV 1). Conclusion: Current HSU data in CF are limited and there is considerable scope for further research, both in providing HSU values for CF and in investigating methods for HSU elicitation/evaluation in CF populations

Check Out the Library, 2016 Fall Issue

Issue 4 New Publications from the HSU Press Humboldt Scholars Lab for HSU Research Opens Digital Media Lab Opening New & Improved Math Tutoring Lab Write on the First Floor Students are Talking Unpacking & Exploring White Privilege Relax & Gain Focus at the Brain Booth L4 HSU Creates Campus Connectionshttps://digitalcommons.humboldt.edu/library_pub/1010/thumbnail.jp

Higher congruences between newforms and Eisenstein series of squarefree level

Let $p\geq 5$ be prime. For elliptic modular forms of weight 2 and level $\Gamma_0(N)$ where $N>6$ is squarefree, we bound the depth of Eisenstein congruences modulo $p$ (from below) by a generalized Bernoulli number with correction factors and show how this depth detects the local non-principality of the Eisenstein ideal. We then use admissibility results of Ribet and Yoo to give an infinite class of examples where the Eisenstein ideal is not locally principal. Lastly, we illustrate these results with explicit computations and give an interesting commutative algebra application related to Hilbert--Samuel multiplicities.Comment: 19 pages. Minor revisions. Accepted for publication in The Journal de Th\'eorie des Nombres de Bordeau

Hsu

Abstract Case studies were done at various MBA universities for 30+ years. These publications and internet searches, added significantly to learning. It is also a good practice to use case studies for undergraduate degree programs. But for the computer logic or programming courses, there were few case studies in the literature. At University of Phoenix, Algorithm Logic for Computer Programming was taught. C# .NET Programming and Java Programming were given at New Jersey Institute Technology. At Dominican College, International Management and Global E-Commerce were offered. Doing case studies in these courses provided a good foundation for critical thinking, communications, interpersonal, leadership, public speaking and team building skills. Student reviews were good to excellent. This paper gives the summary

Check Out the Library, 2017 Spring Issue

Issue 5 Updates from the Academic Technology Team HSU Authors Celebration ideaFest ideaFest Journal News from HSU Press A New Future for Humboldt’s Past 360 Degrees of Innovationhttps://digitalcommons.humboldt.edu/library_pub/1009/thumbnail.jp

Occurrence of the Sinus Nematode Skrjabingylus sp. (Nematoda: Metastrongyloidea) Inferred from Sinus Lesions in Arkansas Mustelidae and Mephitidae, with review of relevant literature

Nasal nematodes of the genus Skrjabingylus occur in the mammalian families Mustelidae and Mephitidae, and have been found from Canada to Costa Rica. Ingestion of infected snails, frogs, snakes, or mice can lead to infection of these mammalian hosts. Infection often causes pathology to bones in the sinus region, which may lead to discoloration, enlargement, and fenestrations of the bone. Examination of museum specimens for bone lesions or other evidence of infection has been used to evidence prior infection, but prevalence and intensity cannot be interpreted without actually recovering the parasite. We examined Mustelids and Mephitids in collections of mammals housed at Arkansas State University (ASU), Henderson State University (HSU), and the University of Arkansas at Little Rock (UALR) to evaluate the possible occurrence of nasal nematodes in Arkansas mammals. Evidence of infection was found in skulls of the Striped Skunk (Mephitis mephitis), Spotted Skunk (Spilogale putorius), Mink (Neovison vison), Long-tailed Weasel (Mustela frenata), and North American River Otter (Lontra canadensis) from Arkansas. We report for the first time evidence of the presence and distribution of Skrjabingylus sp. infecting mammals in Arkansas

Response to "The invalidity of a Mach probe model" [Phys. Plasmas 9, 1832 (2002)]

Hutchinson gives a nice analysis of the (in)validity of Hudis and Lidsky’s unmagnetized Mach probe theory.(1) We agree with his main assertions, which are that (1) a one-dimensional model is incapable of properly describing unmagnetized ion collection by a Mach probe and (2) any experimental agreement with theories based on Hudis and Lidsky should not be interpreted as physical validation of their model