193 research outputs found

    Planning and Interactive Decision-Making in Expert Elementary Physical Education Teachers.

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    This paper describes the planning and interactive decision making used by expert elementary physical education teachers as they developed and taught a 5 day unit on basketball dribbling. Secondly, it explores the relation between teachers\u27 planning productivity (number of statements made) and student achievement. Expert elementary physical education teachers (N = 11) provided information regarding their thought processes during planning and interactive decision making. Planning sessions were conducted prior to each lesson with teachers using the think aloud technique. All instructional lessons were videotaped. Following each of the first three lessons, teachers were shown a videotape of the lesson and were interviewed regarding their thoughts and decision making strategies used during teaching. Students\u27 performance on the AAHPERD Control Dribble Test was used as an indicator of achievement. Students were tested prior to and after the 5 day instructional unit. Results indicated that when planning, the dominant focus of expert teachers was the development of activities. Further, activities rather than formal objectives appear to be the basic unit of instruction by which teachers organize the lesson. During teaching expert teachers were primarily concerned with students\u27 performance. Expert teachers appear to use student behavior cues as the major indication to alter the lesson suggesting that antecedents of alternative actions are content and situation specific. In addition, expert teachers used the class as the focal point when adjusting the original teaching plan. Results from the control dribble test indicated that girls and boys improved significantly in their dribbling skill during the 5 day unit. However, the relation between teacher productivity and student achievement was not significant

    Vol. 27 No. 3 (Autumn 2016), DOI 10.18060/21388 Building an Engagement Center through Love of Place: The Story of the Barbara Weitz Community Engagement Center

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    Universities throughout the United States operate engagement centers to extend campus faculty, staff and student resources to their communities. In 2014, the University of Nebraska Omaha (UNO) opened the Barbara Weitz Community Engagement Center (Weitz CEC): a privately funded $24 million, 70,000 square foot facility located in the middle of its original Dodge Street campus. In addition to offices for its service learning and community service enterprises, the CEC houses over thirty university and community organizations and offers extensive space for meetings, dialogue and collaboration. This paper will discuss its strategic and programmatic origins, unique design, and lessons learned in developing and operating the center

    Working Together: A Values Approach for Strengthening University/Community Partnerships

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    Conference: Coalition of Urban and Metropolitan Universities (CUMU

    Love of Place: The Metropolitan University Advantage: 2015 CUMU National Conference in Omaha

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    The theme for the 2015 CUMU National Conference in Omaha, NE was “Love of Place: The Metropolitan University Advantage”. The 2015 theme celebrates key elements that establish the identity of metropolitan universities and CUMU as an organization. The theme recognizes the unique opportunities and benefits provided by metropolitan universities for students and communities. Metropolitan universities provide students with enriching educational experiences while contributing to building and strengthening the community. These enriched experiences also support faculty and staff growth as members of the university and community. The theme encouraged conference participants to explore new pedagogical approaches, strategies for sustaining meaningful partnerships, and opportunities for successful engagement of the community by examining the transformative power of the relationships between metropolitan universities and their “place.” Essential to this theme is the notion of stewardship and being good stewards of the communities that we live in, that bless our lives, our families, and our universities. The special issue devoted to the theme and notion of “Love of Place” provides an overview of the stewardship witnessed at the conference and then launches into the full article contributions that illustrate the “Love of Place” exemplified by the great presenters and the many initiatives occurring across the CUMU

    Academic Priority: Graduate/Doctoral Research

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    Overview Doctoral Education at UNO: Past, Present, and Future

    Preference elicitation techniques used in valuing children’s health-related quality-of-life: a systematic review

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    BACKGROUND AND OBJECTIVES: Valuing children’s health states for use in economic evaluations is globally relevant and is of particular relevance in jurisdictions where a cost-utility analysis is the preferred form of analysis for decision making. Despite this, the challenges with valuing child health mean that there are many remaining questions for debate about the approach to elicitation of values. The aim of this paper was to identify and describe the methods used to value children’s health states and the specific issues that arise in the use of these methods. METHODS: We conducted a systematic search of electronic databases to identify studies published in English since 1990 that used preference elicitation methods to value child and adolescent (under 18 years of age) health states. Eligibility criteria comprised valuation studies concerning both child-specific patient-reported outcome measures and child health states defined in other ways, and methodological studies of valuation approaches that may or may not have yielded a value set algorithm. RESULTS: A total of 77 eligible studies were identified from which data on country setting, aims, condition (general population or clinically specific), sample size, age of respondents, the perspective that participants were asked to adopt, source of values (respondents who completed the preference elicitation tasks) and methods questions asked were extracted. Extracted data were classified and evaluated using narrative synthesis methods. The studies were classified into three groups: (1) studies comparing elicitation methods (n = 30); (2) studies comparing perspectives (n = 23); and (3) studies where no comparisons were presented (n = 26); selected studies could fall into more than one group. Overall, the studies varied considerably both in methods used and in reporting. The preference elicitation tasks included time trade-off, standard gamble, visual analogue scaling, rating/ranking, discrete choice experiments, best-worst scaling and willingness to pay elicited through a contingent valuation. Perspectives included adults’ considering the health states from their own perspective, adults taking the perspective of a child (own, other, hypothetical) and a child/adolescent taking their own or the perspective of another child. There was some evidence that children gave lower values for comparable health states than did adults that adopted their own perspective or adult/parents that adopted the perspective of children. CONCLUSIONS: Differences in reporting limited the conclusions that can be formed about which methods are most suitable for eliciting preferences for children’s health and the influence of differing perspectives and values. Difficulties encountered in drawing conclusions from the data (such as lack of consensus and poor reporting making it difficult for users to choose and interpret available values) suggest that reporting guidelines are required to improve the consistency and quality of reporting of studies that value children’s health using preference-based techniques. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40273-022-01149-3

    Clinical and genetic heterogeneity in familial focal segmental glomerulosclerosis

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    Clinical and genetic heterogeneity in familial focal segmental glomerulosclerosis.BackgroundFamilial forms of focal segmental glomerulosclerosis (FFSGS) that exhibit autosomal dominant or recessive patterns of inheritance have been described. The genetic basis of these hereditary forms of FSGS is unknown. One recent study of a kindred from Oklahoma with an autosomal dominant form of FSGS linked this disease to a region of chromosome 19q. In addition, polymorphisms in a gene in this region on chromosome 19q13 have been linked to congenital nephrotic syndrome of the Finnish type. We have ascertained and characterized a large family with autosomal dominant FFSGS (Duke 6530).MethodsFamilies were compared for clinical and genetic heterogeneity. To test for linkage of our family to this portion of chromosome 19, genomic DNA was isolated from 102 family members, and polymerase chain reaction was performed using eight microsatellite markers that spanned the area of interest on chromosome 19. Data were evaluated using two-point linkage analysis, multipoint analysis, and an admixture test.ResultsLinkage was excluded at a distance of ±5 to 10cm for all markers tested with two-point log10 of the odds of linkage (LOD) scores and from an approximate 60cm interval in this area of chromosome 19q via multipoint analysis.ConclusionFSGS has been called the “final common pathway” of glomerular injury, as it is a frequent pathological manifestation with diverse etiologies. This diversity likely correlates with the genetic heterogeneity that we have established. Thus, our data demonstrate that there are at least two genes responsible for this disease, and there is genetic as well as clinical heterogeneity in autosomal dominant FSGS

    Targeting effector memory T cells with alefacept in new onset type 1 diabetes: 12 month results from the T1DAL study

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    Background Type 1 diabetes (T1D) results from autoimmune targeting of the pancreatic beta cells, likely mediated by effector memory T cells (Tems). CD2, a T cell surface protein highly expressed on Tems, is targeted by the fusion protein alefacept, depleting Tems and central memory T cells (Tcms). We hypothesized that alefacept would arrest autoimmunity and preserve residual beta cells in newly diagnosed T1D. Methods The T1DAL study is a phase II, double-blind, placebo-controlled trial that randomised T1D patients 12-35 years old within 100 days of diagnosis, 33 to alefacept (two 12-week courses of 15 mg IM per week, separated by a 12-week pause) and 16 to placebo, at 14 US sites. The primary endpoint was the change from baseline in mean 2-hour C-peptide area under the curve (AUC) at 12 months. This trial is registered with ClinicalTrials.gov, number NCT00965458. Findings The mean 2-hour C-peptide AUC at 12 months increased by 0.015 nmol/L (95% CI -0.080 to 0.110 nmol/L) in the alefacept group and decreased by 0.115 nmol/L (95% CI -0.278 to 0.047) in the placebo group, which was not significant (p=0.065). However, key secondary endpoints were met: the mean 4-hour C-peptide AUC was significantly higher (p=0.019), and daily insulin use and the rate of hypoglycemic events were significantly lower (p=0.02 and p<0.001, respectively) at 12 months in the alefacept vs. placebo groups. Safety and tolerability were comparable between groups. There was targeted depletion of Tems and Tcms, with sparing of naĂŻve and regulatory T cells (Tregs). Interpretation At 12 months, alefacept preserved the 4-hour C-peptide AUC, lowered insulin use, and reduced hypoglycemic events, suggesting a signal of efficacy. Depletion of memory T cells with sparing of Tregs may be a useful strategy to preserve beta cell function in new-onset T1D
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