The High Cost of Wisconsin's Dropout Rate

Outlines the scope of the high school dropout problem in Wisconsin and dropouts' risk of unemployment, health problems, and incarceration. Estimates costs to the state through reduced tax revenues, increased Medicaid costs, and high incarceration rates

Finding the Best Fit: Exploring Postsecondary Undermatch in Tennessee

This dissertation explores the prevalence of postsecondary undermatch among recent high school graduates in Tennessee. Postsecondary undermatch occurs when high achieving students choose to attend colleges or universities that are less selective or of lower quality than those at which they are academically eligible to enroll. Using student-level data provided by the Tennessee Higher Education Commission and the Tennessee Student Assistance Corporation, I first investigate variation in undermatch rates when employing different definitions of undermatch. I then examine the effects of two state-sponsored financial aid programs on treated students’ probabilities of undermatch across the state. Implications for policy and directions for future research are presented at length.PHDEducationUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttps://deepblue.lib.umich.edu/bitstream/2027.42/137094/1/ehouse_1.pd

A Program Evaluation of BHC Alhambra Hospital Outpatient Services

A program evaluation of the Behavioral Health Care (BHC) Alhambra Hospital\u27s Outpatient Service program was conducted. The purpose was to evaluate the program implementation, assess the program results, and highlight methods of program improvement. The evaluator conducted focus groups with administrative and clinical program staff and evaluated data utilizing thematic analysis. Three themes, education, programmatic operations, and team highlighted areas of program effectiveness and areas of program improvement. Administrative staff and clinical staff highlighted the importance of training and improved communication between program staff and board and care staff. Recommendations include the administrative staff creating a plan to account for program interruptions, creating a comprehensive training manual for clinical staff, and improving communication between administrative staff and board and care facility staff to better support program implementation

Iron deficiency in parkinsonism : region-specific iron dysregulation in Parkinson's disease and multiple system atrophy

Alpha synuclein pathology is widespread and found in diverse cell types in multiple system atrophy (MSA) as compared to Parkinson's disease (PD). The reason for this differential distribution is unknown. Regional differences in the distribution of iron are associated with neurodegenerative diseases, and here we characterize the relationship between iron homeostasis proteins and regional concentration, distribution and form of iron in MSA and PD. In PD substantia nigra, tissue iron and expression of the iron export protein ferroportin increased, while the iron storage protein ferritin expression was unchanged. In the basis pontis of MSA cases, increased total iron concentration coupled with a disproportionate increase in ferritin in dysmorphic microglia and a reduction in ferroportin expression. This is supported by isothermal remanent magnetisation evidence consistent with elevated concentrations of ferritin-bound iron in MSA basis pontis. Conventional opinion holds that excess iron is involved in neurodegeneration. Our data support that this may be the case in PD. While region-specific changes in iron are evident in both PD and MSA, the mechanisms of iron dysregulation appear quite distinct, with a failure to export iron from the MSA basis pontis coupling with significant intracellular accumulation of ferritin iron. This pattern also occurs, to a lesser extent, in the MSA putamen. Despite the excess tissue iron, the manner of iron dysregulation in MSA is reminiscent of changes in anemia of chronic disease, and our preliminary data, coupled with the widespread pathology and involvement of multiple cell types, may evidence a deficit in bioavailabile iron

The Apparent Involvement of ANMEs in Mineral Dependent Methane Oxidation, as an Analog for Possible Martian Methanotrophy

On Earth, marine anaerobic methane oxidation (AOM) can be driven by the microbial reduction of sulfate, iron, and manganese. Here, we have further characterized marine sediment incubations to determine if the mineral dependent methane oxidation involves similar microorganisms to those found for sulfate-dependent methane oxidation. Through FISH and FISH-SIMS analyses using ^(13)C and ^(15)N labeled substrates, we find that the most active cells during manganese dependent AOM are primarily mixed and mixed-cluster aggregates of archaea and bacteria. Overall, our control experiment using sulfate showed two active bacterial clusters, two active shell aggregates, one active mixed aggregate, and an active archaeal sarcina, the last of which appeared to take up methane in the absence of a closely-associated bacterial partner. A single example of a shell aggregate appeared to be active in the manganese incubation, along with three mixed aggregates and an archaeal sarcina. These results suggest that the microorganisms (e.g., ANME-2) found active in the manganese-dependent incubations are likely capable of sulfate-dependent AOM. Similar metabolic flexibility for Martian methanotrophs would mean that the same microbial groups could inhabit a diverse set of Martian mineralogical crustal environments. The recently discovered seasonal Martian plumes of methane outgassing could be coupled to the reduction of abundant surface sulfates and extensive metal oxides, providing a feasible metabolism for present and past Mars. In an optimistic scenario Martian methanotrophy consumes much of the periodic methane released supporting on the order of 10,000 microbial cells per cm2 of Martian surface. Alternatively, most of the methane released each year could be oxidized through an abiotic process requiring biological methane oxidation to be more limited. If under this scenario, 1% of this methane flux were oxidized by biology in surface soils or in subsurface aquifers (prior to release), a total of about 10^(20) microbial cells could be supported through methanotrophy with the cells concentrated in regions of methane release

Convener

Silas House will be convening this session of three of his best students, all Appalachian Studies minors at Berea College

An analysis of the relationships between peer support and diabetes outcomes in adolescents with type 1 diabetes

This study explores the relationships between the various subtypes of global and diabetes-specific peer support and health outcomes in adolescents with type 1 diabetes. Global peer support significantly predicted self-care and glycated haemoglobin, although no associations were identified for diabetes-specific support overall, nor its factors. When comparing participants with above or below average glycaemic control, significantly greater diabetes-specific support was reported in those with poorer control. It is suggested that this may be related to feelings of nagging, in which diabetes-specific support is perceived as harassment

Manganese- and iron-dependent marine methane oxidation

Anaerobic methanotrophs help regulate Earth’s climate and may have been an important part of the microbial ecosystem on the early Earth. The anaerobic oxidation of methane (AOM) is often thought of as a sulfate-dependent process, despite the fact that other electron acceptors are more energetically favorable. Here, we show that microorganisms from marine methane-seep sediment in the Eel River Basin in California are capable of using manganese (birnessite) and iron (ferrihydrite) to oxidize methane, revealing that marine AOM is coupled, either directly or indirectly, to a larger variety of oxidants than previously thought. Large amounts of manganese and iron are provided to oceans from rivers, indicating that manganese- and iron-dependent AOM have the potential to be globally important

This article corrects: “Correlation of the NBME Advanced Clinical Examination in EM and the National EM M4 examsâ€?

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This article corrects: “Correlation of the NBME Advanced Clinical Examination in EM and the National EM M4 examsâ€?

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