Fiscal science and technology expenditure and the spatial convergence of regional innovation efficiency: evidence from China’s province-level data

Narrowing the gap in regional innovation efficiency is conducive to the coordinated development of regional economies. Fiscal science and technology (S&T) expenditure is the government’s primary means of supporting regional innovation. It also plays an essential role in improving the efficiency of regional innovation. This study constructs a spatial convergence economic model based on a dynamic perspective. It also examines the relationship between fiscal S&T expenditure and spatial convergence of regional innovation efficiency. China’s regional innovation efficiency shows a trend of conditional b-convergence. Fiscal S&T expenditure positively affects the spatial convergence of regional innovation efficiency and has an inverted U-shaped, nonlinear relationship as a whole. The transmission mechanism test revealed that the cross-regional flow of research and development (R&D) personnel can enhance this positive effect, and the role of R&D capital is not significant

Edible Bird’s Nest Prevents Menopause-Related Memory and Cognitive Decline in Rats via Increased Hippocampal Sirtuin-1 Expression

Menopause causes cognitive and memory dysfunction due to impaired neuronal plasticity in the hippocampus. Sirtuin-1 (SIRT1) downregulation in the hippocampus is implicated in the underlying molecular mechanism. Edible bird’s nest (EBN) is traditionally used to improve general wellbeing, and in this study, we evaluated its effects on SIRT1 expression in the hippocampus and implications on ovariectomy-induced memory and cognitive decline in rats. Ovariectomized female Sprague-Dawley rats were fed with normal pellet alone or normal pellet + EBN (6, 3, or 1.5%), compared with estrogen therapy (0.2 mg/kg/day). After 12 weeks of intervention, Morris water maze (four-day trial and one probe trial) was conducted, and serum estrogen levels, toxicity markers (alanine transaminase, alkaline phosphatase, urea, and creatinine), and hippocampal SIRT1 immunohistochemistry were estimated after sacrifice. The results indicated that EBN and estrogen enhanced spatial learning and memory and increased serum estrogen and hippocampal SIRT1 expression. In addition, the EBN groups did not show as much toxicity to the liver as the estrogen group. The data suggested that EBN treatment for 12 weeks could improve cognition and memory in ovariectomized female rats and may be an effective alternative to estrogen therapy for menopause-induced aging-related memory loss

Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade

The Hippo pathway senses cellular conditions and regulates YAP/TAZ to control cellular and tissue homeostasis, while TBK1 is central for cytosolic nucleic acid sensing and antiviral defence. The correlation between cellular nutrient/physical status and host antiviral defence is interesting but not well understood. Here we find that YAP/TAZ act as natural inhibitors of TBK1 and are vital for antiviral physiology. Independent of transcriptional regulation and through the transactivation domain, YAP/TAZ associate directly with TBK1 and abolish virus-induced TBK1 activation, by preventing TBK1 Lys63-linked ubiquitylation and the binding of adaptors/substrates. Accordingly, YAP/TAZ deletion/depletion or cellular conditions inactivating YAP/TAZ through Lats1/2 kinases relieve TBK1 suppression and boost antiviral responses, whereas expression of the transcriptionally inactive YAP dampens cytosolic RNA/DNA sensing and weakens the antiviral defence in cells and zebrafish. Thus, we describe a function of YAP/TAZ and the Hippo pathway in innate immunity, by linking cellular nutrient/physical status to antiviral host defence

Household, community, sub-national and country-level predictors of primary cooking fuel switching in nine countries from the PURE study

Introduction. Switchingfrom polluting (e.g. wood, crop waste, coal)to clean (e.g. gas, electricity) cooking fuels can reduce household air pollution exposures and climate-forcing emissions.While studies have evaluated specific interventions and assessed fuel-switching in repeated cross-sectional surveys, the role of different multilevel factors in household fuel switching, outside of interventions and across diverse community settings, is not well understood. Methods.We examined longitudinal survey data from 24 172 households in 177 rural communities across nine countries within the Prospective Urban and Rural Epidemiology study.We assessed household-level primary cooking fuel switching during a median of 10 years offollow up (∼2005–2015).We used hierarchical logistic regression models to examine the relative importance of household, community, sub-national and national-level factors contributing to primary fuel switching. Results. One-half of study households(12 369)reported changing their primary cookingfuels between baseline andfollow up surveys. Of these, 61% (7582) switchedfrom polluting (wood, dung, agricultural waste, charcoal, coal, kerosene)to clean (gas, electricity)fuels, 26% (3109)switched between different polluting fuels, 10% (1164)switched from clean to polluting fuels and 3% (522)switched between different clean fuels

IMPACT OF REGIONAL CENTRES ON THE QUALITY OF LIFE

Bachelor'sBACHELOR OF SCIENCE (REAL ESTATE

The Impact of Green Finance on Industrial Land Use Efficiency: Evidence from 279 Cities in China

Improving the efficiency of industrial land use is of great significance to the sustainable development of cities. Based on a financial perspective, this paper studies the relationship between green finance and urban industrial land use efficiency (UILUE). First, the epsilon-based measure model was used to calculate the UILUE of 279 cities in China from 2011 to 2020, and then an empirical model is constructed to test the impact and path mechanism of green finance on UILUE. The research results show that green finance can improve the UILUE. The mediation effect test shows that the optimization of industrial structure and technological innovation are the key paths for green finance to affect UILUE. In addition, land finance inhibits the positive effect of green finance on the UILUE. This study provides new evidence for the role green finance plays in improving the efficiency of industrial land use and promoting the sustainable development of cities

Digital finance and regional economic resilience: Evidence from 283 cities in China

Digital technology provided a new driver for the rapid recovery of the global economy in the post-COVID-19 era. This study examined how digital financing affected regional economic resilience. First, this study constructs a multidimensional regional economic resilience evaluation system and measures the economic resilience levels of 283 Chinese cities for 2012-2021–using the entropy value method. Then, panel data, mediation effect, and threshold effect models were constructed to empirically test the impact mechanism of digital finance (DF) on regional economic resilience. The results show that DF improves regional economic resilience, which is more evident in central and western cities. Capital allocation efficiency, regional innovation, and regional consumption are effective paths, whereas DF affects regional economic resilience by enhancing capital allocation efficiency, strengthening regional innovation capacity, and promoting resident consumption. It is worth noting that excessive financialization can mask the role of DF. These conclusions provide new evidence clarifying the role of DF in promoting rapid economic recovery in the post-COVID-19 era

Research on the Status of European and Chinese Trade Competition in the Third Party Market

China’s increasingly important role in the global economy has changed the nature of global competition and reshaped international trade. At the same time, the EU has long been the most important force in global trade and continues to maintain a very large trade surplus. We discussed whether China is an increasingly important competitor of Europe in third-party markets, especially Latin America. More specifically, we have empirically estimated the elasticity of substitution between European exports and Chinese exports to Latin American economies (i.e. Their response to Latin American exports to changes in relative export prices). The results of this article show that over time, the competition between China and the EU in Latin America has increased. Before 2007, the competition between China and the EU was relatively high. Less, this reflects to a certain extent the fact that China mainly exports inferior products. However, since 2007, the substitution elasticity has increased, reflecting China ’s rise in the value chain upstream. We also studied China and the EU’s. The competition between the key industries of the EU exported by the Americas. We found that the competition between China and Europe in the field of motors and road vehicles is more intense. This should be sought Global level to maintain the competitiveness of European sounded the alarm

The Effect of Folk Belief on Social Trust: The Mediating Role of Social Support and the Sense of Identity

Although the influential factors of social trust have aroused heated discussion, the research on the influence of religious belief, especially Chinese folk belief, on social trust and the mechanism between the two is relatively insufficient. This study aims to explore the influence of folk beliefs on Chinese residents’ social trust and the mediating role of social support and the sense of identity. The empirical analysis of 23,823 Chinese residents shows that there is a significant positive correlation between folk belief and social trust. Social support and a sense of identity play a mediating role between folk beliefs and residents’ social trust. People with folk beliefs can significantly promote their social trust by improving their degree of social support and their sense of identity. In addition, the influence of folk belief on the social trust of residents in eastern, northern China and rural areas is more significant, showing regional and registered residence heterogeneity. Therefore, we should correctly interpret and popularize the core spirit and social and cultural significance of folk belief to form a bond of social trust. At the same time, folk beliefs can be returned to the people, which will help people find a sense of belonging and sense of identity and enhance their social trust