Buerger's disease manifesting nodular erythema with livedo reticularis

ArticleINTERNAL MEDICINE. 46(21):1815-1819(2007)journal articl

Shear viscosity, instability and the upper bound of the Gauss-Bonnet coupling constant

We compute the dimensionality dependence of $\eta/s$ for charged black branes with Gauss-Bonnet correction. We find that both causality and stability constrain the value of Gauss-Bonnet coupling constant to be bounded by 1/4 in the infinite dimensionality limit. We further show that higher dimensionality stabilize the gravitational perturbation. The stabilization of the perturbation in higher dimensional space-time is a straightforward consequence of the Gauss-Bonnet coupling constant bound.Comment: 16 pages,3 figures+3 tables,typos corrected, published versio

Holographic Nuclear Physics

We analyze the phases of the Sakai-Sugimoto model at finite temperature and baryon chemical potential. Baryonic matter is represented either by 4-branes in the 8-branes or by strings stretched from the 8-branes to the horizon. We find the explicit configurations and use them to determine the phase diagram and equation of state of the model. The 4-brane configuration (nuclear matter) is always preferred to the string configuration (quark matter), and the latter is also unstable to density fluctuations. In the deconfined phase the phase diagram has three regions corresponding to the vacuum, quark-gluon plasma, and nuclear matter, with a first-order and a second-order phase transition separating the phases. We find that for a large baryon number density, and at low temperatures, the dominant phase has broken chiral symmetry. This is in qualitative agreement with studies of QCD at high density.Comment: 27 pages, 26 figures. v2: Added a comment about higher derivative corrections to the DBI action in the smeared instanton in section 2.1. v3: References added, version published in JHEP. v4: misprints correcte

Criticality, Scaling and Chiral Symmetry Breaking in External Magnetic Field

We consider a D7-brane probe of $AdS_{5}\times S^5$ in the presence of pure gauge $B$-field. The dual gauge theory is flavored Yang-Mills theory in external magnetic field. We explore the dependence of the fermionic condensate on the bare quark mass $m_{q}$ and study the discrete self-similar behavior of the theory near the origin of the parametric space. We calculate the critical exponents of the bare quark mass and the fermionic condensate. A study of the meson spectrum supports the expectation based on thermodynamic considerations that at zero bare quark mass the stable phase of the theory is a chiral symmetry breaking one. Our study reveals the self-similar structure of the spectrum near the critical phase of the theory, characterized by zero fermionic condensate and we calculate the corresponding critical exponent of the meson spectrum.Comment: 29 pages, 9 figures. Accepted in JHEP. Updated to mach the published version. One figure added, some definitions improve

Adding flavour to the Polchinski-Strassler background

As an extension of holography with flavour, we analyze in detail the embedding of a D7-brane probe into the Polchinski-Strassler gravity background, in which the breaking of conformal symmetry is induced by a 3-form flux G_3. This corresponds to giving masses to the adjoint chiral multiplets. We consider the N=2 supersymmetric case in which one of the adjoint chiral multiplets is kept massless while the masses of the other two are equal. This setup requires a generalization of the known expressions for the backreaction of G_3 in the case of three equal masses to generic mass values. We work to second order in the masses to obtain the embedding of D7-brane probes in the background. At this order, the 2-form potentials corresponding to the background flux induce an 8-form potential which couples to the worldvolume of the D7-branes. We show that the embeddings preserve an SU(2) x SU(2) symmetry. We study possible embeddings both analytically in a particular approximation, as well as numerically. The embeddings preserve supersymmetry, as we investigate using the approach of holographic renormalization. The meson spectrum associated to one of the embeddings found reflects the presence of the adjoint masses by displaying a mass gap.Comment: LaTeX, 50 pages, 9 figure

Holographic Hadrons in a Confining Finite Density Medium

We study a sector of the hadron spectrum in the presence of finite baryon density. We use a non-supersymmetric gravity dual to a confining guage theory which exhibits a running dilaton. The interaction of mesons with the finite density medium is encoded in the dual theory by a force balancing between flavor D7-branes and a baryon vertex provided by a wrapped D5-brane. When the current quark mass m_q is sufficiently large, the meson mass reduces, exhibiting an interesting spectral flow as we increase the baryon density while it has a more complicated behaviour for very small m_q.Comment: 34 pages, 20 figures, errors for some figures are fixe

Nuclear matter to strange matter transition in holographic QCD

We construct a simple holographic QCD model to study nuclear matter to strange matter transition. The interaction of dense medium and hadrons is taken care of by imposing the force balancing condition for stable D4/D6/D6 configuration. By considering the intermediate and light flavor branes interacting with baryon vertex homogeneously distributed along R^3 space and requesting the energy minimization, we find that there is a well defined transition density as a function of current quark mass. We also find that as density goes up very high, intermediate (or heavy) and light quarks populate equally as expected from the Pauli principle. In this sense, the effect of the Pauli principle is realized as dynamics of D-branes.Comment: 13 pages, 14 figure

Efficacy of weekly docetaxel in locally advanced cardiac angiosarcoma

Background: Primary cardiac angiosarcoma is extremely aggressive; however, it is often misdiagnosed because of its rarity. For locally advanced tumors, doxorubicin-based chemotherapy regimens are the standard of treatment, even if the gain in term of progression-free survival is limited and is no longer than 5 months. Case presentation: We report the case of a Caucasian 23-year-old man with locally advanced cardiac angiosarcoma who underwent radical surgical resection after a prolonged response to weekly docetaxel and complementary radiotherapy. Conclusion: Combined treatment with weekly docetaxel and radiotherapy may be a valid alternative for the treat-ment of locally advanced cardiac angiosarcoma; the combination can lead to radical surgical resections, avoiding the cumulative cardiotoxicity of antracycline-based regimens

Inverse magnetic catalysis in dense holographic matter

We study the chiral phase transition in a magnetic field at finite temperature and chemical potential within the Sakai-Sugimoto model, a holographic top-down approach to (large-N_c) QCD. We consider the limit of a small separation of the flavor D8-branes, which corresponds to a dual field theory comparable to a Nambu-Jona Lasinio (NJL) model. Mapping out the surface of the chiral phase transition in the parameter space of magnetic field strength, quark chemical potential, and temperature, we find that for small temperatures the addition of a magnetic field decreases the critical chemical potential for chiral symmetry restoration - in contrast to the case of vanishing chemical potential where, in accordance with the familiar phenomenon of magnetic catalysis, the magnetic field favors the chirally broken phase. This "inverse magnetic catalysis" (IMC) appears to be associated with a previously found magnetic phase transition within the chirally symmetric phase that shows an intriguing similarity to a transition into the lowest Landau level. We estimate IMC to persist up to 10^{19} G at low temperatures.Comment: 42 pages, 11 figures, v3: extended discussion; new appendix D; references added; version to appear in JHE