1,277 research outputs found
Exact Equal Time Statistics of Orszag-McLaughlin Dynamics By The Hopf Characteristic Functional Approach
By employing Hopf's functional method, we find the exact characteristic
functional for a simple nonlinear dynamical system introduced by Orszag.
Steady-state equal-time statistics thus obtained are compared to direct
numerical simulation. The solution is both non-trivial and strongly
non-Gaussian.Comment: 6 pages and 2 figure
Classification of integrable Weingarten surfaces possessing an sl(2)-valued zero curvature representation
In this paper we classify Weingarten surfaces integrable in the sense of
soliton theory. The criterion is that the associated Gauss equation possesses
an sl(2)-valued zero curvature representation with a nonremovable parameter.
Under certain restrictions on the jet order, the answer is given by a third
order ordinary differential equation to govern the functional dependence of the
principal curvatures. Employing the scaling and translation (offsetting)
symmetry, we give a general solution of the governing equation in terms of
elliptic integrals. We show that the instances when the elliptic integrals
degenerate to elementary functions were known to nineteenth century geometers.
Finally, we characterize the associated normal congruences
The general classical solution of the superparticle
The theory of vectors and spinors in 9+1 dimensional spacetime is introduced
in a completely octonionic formalism based on an octonionic representation of
the Clifford algebra \Cl(9,1). The general solution of the classical
equations of motion of the CBS superparticle is given to all orders of the
Grassmann hierarchy. A spinor and a vector are combined into a
Grassmann, octonionic, Jordan matrix in order to construct a superspace
variable to describe the superparticle. The combined Lorentz and supersymmetry
transformations of the fermionic and bosonic variables are expressed in terms
of Jordan products.Comment: 11 pages, REVTe
Differentiation Potential of Pancreatic Fibroblastoid Cells/Stellate Cells: Effects of Peroxisome Proliferator-Activated Receptor Gamma Ligands
Pancreatic stellate cells have been investigated mostly for their activation process, supposed to support the development of pancreatic disease. Few studies have been presented on reversal of the activation process in vitro. Thiazolidinediones (TZDs) have been used as antidiabetics and have now been reported to exert antifibrotic activity. We tested effects of natural and synthetic ligands of peroxisome proliferator-activated receptor gamma (PPARγ) on human pancreatic fibroblastoid cells (hPFCs) in search for specificity of action. Ciglitazone, as a prototype of TZDs, was shown to have reversible growth inhibitory effects on human pancreatic fibroblastoid cells/stellate cells. Cells treated with ciglitazone for three days showed enhanced lipid content and induction of proteins involved in lipid metabolism. Collagen synthesis was reduced in hPFC. Interaction of PPARγ with DNA binding sites upon ligand binding was shown by gel shift analysis. These findings point toward a potential for adipocyte differentiation in human pancreatic fibroblastoid cells
Relativistic ponderomotive force, uphill acceleration, and transition to chaos
Starting from a covariant cycle-averaged Lagrangian the relativistic
oscillation center equation of motion of a point charge is deduced and
analytical formulae for the ponderomotive force in a travelling wave of
arbitrary strength are presented. It is further shown that the ponderomotive
forces for transverse and longitudinal waves are different; in the latter,
uphill acceleration can occur. In a standing wave there exists a threshold
intensity above which, owing to transition to chaos, the secular motion can no
longer be described by a regular ponderomotive force.
PACS number(s): 52.20.Dq,05.45.+b,52.35.Mw,52.60.+hComment: 8 pages, RevTeX, 3 figures in PostScript, see also
http://www.physik.th-darmstadt.de/tqe
A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits.
Corticotrophin-releasing factor (CRF) is a 41 amino acid neuropeptide that coordinates adaptive responses to stress. CRF projections from neurons in the central nucleus of the amygdala (CeA) to the brainstem are of particular interest for their role in motivated behavior. To directly examine the anatomy and function of CRF neurons, we generated a BAC transgenic Crh-Cre rat in which bacterial Cre recombinase is expressed from the Crh promoter. Using Cre-dependent reporters, we found that Cre expressing neurons in these rats are immunoreactive for CRF and are clustered in the lateral CeA (CeL) and the oval nucleus of the BNST. We detected major projections from CeA CRF neurons to parabrachial nuclei and the locus coeruleus, dorsal and ventral BNST, and more minor projections to lateral portions of the substantia nigra, ventral tegmental area, and lateral hypothalamus. Optogenetic stimulation of CeA CRF neurons evoked GABA-ergic responses in 11% of non-CRF neurons in the medial CeA (CeM) and 44% of non-CRF neurons in the CeL. Chemogenetic stimulation of CeA CRF neurons induced Fos in a similar proportion of non-CRF CeM neurons but a smaller proportion of non-CRF CeL neurons. The CRF1 receptor antagonist R121919 reduced this Fos induction by two-thirds in these regions. These results indicate that CeL CRF neurons provide both local inhibitory GABA and excitatory CRF signals to other CeA neurons, and demonstrate the value of the Crh-Cre rat as a tool for studying circuit function and physiology of CRF neurons
Convergence of Quantum Annealing with Real-Time Schrodinger Dynamics
Convergence conditions for quantum annealing are derived for optimization
problems represented by the Ising model of a general form. Quantum fluctuations
are introduced as a transverse field and/or transverse ferromagnetic
interactions, and the time evolution follows the real-time Schrodinger
equation. It is shown that the system stays arbitrarily close to the
instantaneous ground state, finally reaching the target optimal state, if the
strength of quantum fluctuations decreases sufficiently slowly, in particular
inversely proportionally to the power of time in the asymptotic region. This is
the same condition as the other implementations of quantum annealing, quantum
Monte Carlo and Green's function Monte Carlo simulations, in spite of the
essential difference in the type of dynamics. The method of analysis is an
application of the adiabatic theorem in conjunction with an estimate of a lower
bound of the energy gap based on the recently proposed idea of Somma et. al.
for the analysis of classical simulated annealing using a classical-quantum
correspondence.Comment: 6 pages, minor correction
Insecurity for compact surfaces of positive genus
A pair of points in a riemannian manifold is secure if the geodesics
between the points can be blocked by a finite number of point obstacles;
otherwise the pair of points is insecure. A manifold is secure if all pairs of
points in are secure. A manifold is insecure if there exists an insecure
point pair, and totally insecure if all point pairs are insecure.
Compact, flat manifolds are secure. A standing conjecture says that these are
the only secure, compact riemannian manifolds. We prove this for surfaces of
genus greater than zero. We also prove that a closed surface of genus greater
than one with any riemannian metric and a closed surface of genus one with
generic metric are totally insecure.Comment: 37 pages, 11 figure
Constraint and gauge shocks in one-dimensional numerical relativity
We study how different types of blow-ups can occur in systems of hyperbolic
evolution equations of the type found in general relativity. In particular, we
discuss two independent criteria that can be used to determine when such
blow-ups can be expected. One criteria is related with the so-called geometric
blow-up leading to gradient catastrophes, while the other is based upon the
ODE-mechanism leading to blow-ups within finite time. We show how both
mechanisms work in the case of a simple one-dimensional wave equation with a
dynamic wave speed and sources, and later explore how those blow-ups can appear
in one-dimensional numerical relativity. In the latter case we recover the well
known ``gauge shocks'' associated with Bona-Masso type slicing conditions.
However, a crucial result of this study has been the identification of a second
family of blow-ups associated with the way in which the constraints have been
used to construct a hyperbolic formulation. We call these blow-ups ``constraint
shocks'' and show that they are formulation specific, and that choices can be
made to eliminate them or at least make them less severe.Comment: 19 pages, 8 figures and 1 table, revised version including several
amendments suggested by the refere
- …