How Practice Diffusion Drives IoT Technology Adoption and Institutionalization of Solutions in Service Ecosystems

This paper proposes a framework for considering how practice diffusion drives the adoption of IoT technology and fuels institutionalization of solutions within service ecosystems. Practice diffusion requires the adaptation of a practice (using a wearable device) as it emerges across distinct sociocultural contexts. The adaptation of practices allows for the adoption of technology in different ways. New materials are linked with pre-existing meanings and competences as practices emerge and become embedded within a social structure. For IoT technologies, materials include a device and its associated digital data. Thus, practice adaptation requires linkages that enable the integration and use of both a device and data. We highlight a growing mental health crisis and the potential of wearable devices as medical aids, particularly for adolescents who spend much of their time connected to the internet. We consider important linkages to help institutionalize unique solutions for those in need

The Role of Families in Youth Sport Programming in a Canadian Aboriginal Reserve

Background: There has been a recent push in the sport psychology literature for sport participants to be approached based on their cultural backgrounds. However, there are few examples where a cultural approach is considered, such as a culturally reflexive version of participatory action research (PAR). In the current study, the role of family is considered in relation to the sport engagement of Canadian Aboriginal youth. Methods: Mainstream researchers teamed with co-researchers from the Wikwemikong Unceded Indian Reserve for 5 years. Community meetings and talking circles were employed as culturally sensitive data collection techniques to uncover how to encourage youth participation in Wikwemikong’s sport programs. The overarching methodology for the project is PAR. Results: Themes and subthemes were determined by community consensus with terms indigenous (ie, culturally relevant) among the local Aboriginal culture. Family was considered important for youth involvement in Aboriginal community sport programs. Parents were expected to support their children by managing schedules and priorities, providing transportation, financial support, encouragement, and being committed to the child’s activity. Aunts, uncles, cousins, siblings, grandparents, and the family as a whole were seen as sharing the responsibility to retain youth in sport through collateral support (ie, when gaps in parental support arose). Conclusions: Suggestions are proposed regarding how families in Aboriginal communities can collaborate to facilitate sport and physical activity among their youth. Further suggestions are proposed for researchers engaging in culturally reflexive research with participants and coresearchers from oppressed cultures

Student nurses' experience of simulation in preparation for practice

At the University of Huddersfield the acquisition of skills and underpinning knowledge through simulation has been firmly embedded into the pre-registration nursing curriculum. This workshop will provide a summary of a pilot project on student evaluation, and the outcomes from a phenomenological study involving final year nursing students’ experiences of simulation throughout the curriculum. Simulation took several differing approaches in order to maximize learning opportunities and provide innovative assessment strategie

Photoluminescent DNA binding and cytotoxic activity of a platinum(ii) complex bearing a tetradentate β-diketiminate ligand

A platinum(II) complex of a monoanionic, tetradentate β-diketiminate (BDI) ligand with pendant quinoline arms, BDIQQH, is reported. The complex, [Pt(BDI[superscript QQ])]Cl, is emissive in DMSO, but non-emissive in aqueous buffer. Upon binding DNA in buffer, however, a 150-fold turn-on in emission intensity occurs. Dynamic light scattering and [superscript 1]H NMR spectroscopy indicate that [Pt(BDI[superscript QQ])]Cl forms non-emissive aggregates in aqueous solution; DNA-binding disperses the aggregates leading to the large emission turn-on response. The cytotoxic activity of the complex, measured in two cancer cell lines, is comparable to or better than that of the established anticancer drug cisplatin.National Cancer Institute (U.S.) (Grant CA034992)David H. Koch Graduate FellowshipNational Institutes of Health (U.S.) (Grant 1S10RR13886

Picocyanobacteria and deep-ocean fluorescent dissolved organic matter share similar optical properties

Marine chromophoric dissolved organic matter (CDOM) and its related fluorescent components (FDOM), which are widely distributed but highly photobleached in the surface ocean, are critical in regulating light attenuation in the ocean. However, the origins of marine FDOM are still under investigation. Here we show that cultured picocyanobacteria, Synechococcus and Prochlorococcus, release FDOM that closely match the typical fluorescent signals found in oceanic environments. Picocyanobacterial FDOM also shows comparable apparent fluorescent quantum yields and undergoes similar photo-degradation behaviour when compared with deep-ocean FDOM, further strengthening the similarity between them. Ultrahigh-resolution mass spectrometry (MS) and nuclear magnetic resonance spectroscopy reveal abundant nitrogen-containing compounds in Synechococcus DOM, which may originate from degradation products of the fluorescent phycobilin pigments. Given the importance of picocyanobacteria in the global carbon cycle, our results indicate that picocyanobacteria are likely to be important sources of marine autochthonous FDOM, which may accumulate in the deep ocean

Correlated cryogenic fluorescence microscopy and electron cryo-tomography shows that exogenous TRIM5α can form hexagonal lattices or autophagy aggregates in vivo

Members of the tripartite motif (TRIM) protein family have been shown to assemble into structures in both the nucleus and cytoplasm. One TRIM protein family member, TRIM5α, has been shown to form cytoplasmic bodies involved in restricting retroviruses such as HIV-1. Here we applied cryogenic correlated light and electron microscopy, combined with electron cryo-tomography, to intact mammalian cells expressing YFP-rhTRIM5α and found the presence of hexagonal nets whose arm lengths were similar to those of the hexagonal nets formed by purified TRIM5α in vitro. We also observed YFP-rhTRIM5α within a diversity of structures with characteristics expected for organelles involved in different stages of macroautophagy, including disorganized protein aggregations (sequestosomes), sequestosomes flanked by flat double-membraned vesicles (sequestosome:phagophore complexes), sequestosomes within double-membraned vesicles (autophagosomes), and sequestosomes within multivesicular autophagic vacuoles (amphisomes or autolysosomes). Vaults were also seen in these structures, consistent with their role in autophagy. Our data 1) support recent reports that TRIM5α can form both well-organized signaling complexes and nonsignaling aggregates, 2) offer images of the macroautophagy pathway in a near-native state, and 3) reveal that vaults arrive early in macroautophagy

Visible camera cryostat design and performance for the SuMIRe Prime Focus Spectrograph (PFS)

We describe the design and performance of the SuMIRe Prime Focus Spectrograph (PFS) visible camera cryostats. SuMIRe PFS is a massively multi-plexed ground-based spectrograph consisting of four identical spectrograph modules, each receiving roughly 600 fibers from a 2394 fiber robotic positioner at the prime focus. Each spectrograph module has three channels covering wavelength ranges 380~nm -- 640~nm, 640~nm -- 955~nm, and 955~nm -- 1.26~um, with the dispersed light being imaged in each channel by a f/1.07 vacuum Schmidt camera. The cameras are very large, having a clear aperture of 300~mm at the entrance window, and a mass of $\sim$280~kg. In this paper we describe the design of the visible camera cryostats and discuss various aspects of cryostat performance

The Effect of Low Birthweight on the Health, Behavior, and School Performance of School-Aged Children

This study uses the 1988 Child Health Supplement of the National Health Interview Survey to examine the performance of school-aged children who were of low birthweight. We examine a number of indicators of school performance, health, and behavior. We examine these effects separately for children ages 6 to 10 and for children ages 11 to 15. In addition, we examine two sets of the age cohorts: one where all children are included, and one which excludes children who are attending special education. The latter category is meant to examine children who have not been identified as having problems in school which require special services. We find that low birthweight children are more likely to perform poorly in school than their normal birthweight peers, and they are more likely to experience health problems, even into their adolescence. We do not find significantly more behavior problems for low birthweight children compared to their normal birthweight peers.

The Special Education Costs of Low Birthweight

This paper investigates the relationship between low birthweight, enrollment in special education and special education costs in the united states. we use the Child Health Supplement to the 1988 National Health Interview Survey, obtaining a sample of approximately 8,000 children aged 6 to 15 who are in school. For these children, we calculate the probability of attending special education, holding constant, individual, family and regional variables. We find that children who weighed less than 2500 grams at birth are almost; fifty percent more likely to be enrolled in any type of special education than children who were of normal weight at birth. Since previous studies have found the incremental cost, of special education (1989-1990) to be $4,350 per student, this results in an incremental cost; of special education of$370.8 million (1989-1990) per year due to low birth weight, holding other characteristics constant, these costs, which were conservatively estimated, imply that previous studies, which considered only medical expenditures, substantially underestimate the full cost; of low birthweight.