333 research outputs found

    A Position-Space Renormalization-Group Approach for Driven Diffusive Systems Applied to the Asymmetric Exclusion Model

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    This paper introduces a position-space renormalization-group approach for nonequilibrium systems and applies the method to a driven stochastic one-dimensional gas with open boundaries. The dynamics are characterized by three parameters: the probability α\alpha that a particle will flow into the chain to the leftmost site, the probability β\beta that a particle will flow out from the rightmost site, and the probability pp that a particle will jump to the right if the site to the right is empty. The renormalization-group procedure is conducted within the space of these transition probabilities, which are relevant to the system's dynamics. The method yields a critical point at αc=βc=1/2\alpha_c=\beta_c=1/2,in agreement with the exact values, and the critical exponent ν=2.71\nu=2.71, as compared with the exact value ν=2.00\nu=2.00.Comment: 14 pages, 4 figure

    Breakdown of thermodynamic equilibrium for DNA hybridization in microarrays

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    Test experiments of hybridization in DNA microarrays show systematic deviations from the equilibrium isotherms. We argue that these deviations are due to the presence of a partially hybridized long-lived state, which we include in a kinetic model. Experiments confirm the model predictions for the intensity vs. free energy behavior. The existence of slow relaxation phenomena has important consequences for the specificity of microarrays as devices for the detection of a target sequence from a complex mixture of nucleic acids.Comment: 4 pages, 4 figure

    Note on the stratigraphic position of the Zonderschot sands member of the Berchem formation (Miocene, Belgium)

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    Planktonic foraminifera are recorded from three samples of the Zonderschot Sands Member of the Berchem Formation in the type locality at Zonderschot. Altogether 15 taxa are described. The association of planktonic foraminifera indicates a provincial Globigerinoides trilobus trilobus / Globigerinoides altiaperturus Biozone

    Thermodynamics of histories for the one-dimensional contact process

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    The dynamical activity K(t) of a stochastic process is the number of times it changes configuration up to time t. It was recently argued that (spin) glasses are at a first order dynamical transition where histories of low and high activity coexist. We study this transition in the one-dimensional contact process by weighting its histories by exp(sK(t)). We determine the phase diagram and the critical exponents of this model using a recently developed approach to the thermodynamics of histories that is based on the density matrix renormalisation group. We find that for every value of the infection rate, there is a phase transition at a critical value of s. Near the absorbing state phase transition of the contact process, the generating function of the activity shows a scaling behavior similar to that of the free energy in an equilibrium system near criticality.Comment: 16 pages, 7 figure

    Probing Hybridization parameters from microarray experiments: nearest neighbor model and beyond

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    In this article it is shown how optimized and dedicated microarray experiments can be used to study the thermodynamics of DNA hybridization for a large number of different conformations in a highly parallel fashion. In particular, free energy penalties for mismatches are obtained in two independent ways and are shown to be correlated with values from melting experiments in solution reported in the literature. The additivity principle, which is at the basis of the nearest-neighbor model, and according to which the penalty for two isolated mismatches is equal to the sum of the independent penalties, is thoroughly tested. Additivity is shown to break down for a mismatch distance below 5 nt. The behavior of mismatches in the vicinity of the helix edges, and the behavior of tandem mismatches are also investigated. Finally, some thermodynamic outlying sequences are observed and highlighted. These sequences contain combinations of GA mismatches. The analysis of the microarray data reported in this article provides new insights on the DNA hybridization parameters and can help to increase the accuracy of hybridization-based technologies.Comment: 13 pages, 11 figures, 1 table, Supplementary Data available in Appendi

    Heat risk assessment for the Brussels capital region under different urban planning and greenhouse gas emission scenarios

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    Urban residents are exposed to higher levels of heat stress in comparison to the rural population. As this phenomenon could be enhanced by both global greenhouse gas emissions (GHG) and urban expansion, urban planners and policymakers should integrate both in their assessment. One way to consider these two concepts is by using urban climate models at a high resolution. In this study, the influence of urban expansion and GHG emission scenarios is evaluated at 100 m spatial resolution for the city of Brussels (Belgium) in the near (2031-2050) and far (2081-2100) future. Two possible urban planning scenarios (translated into local climate zones, LCZs) in combination with two representative concentration pathways (RCPs 4.5 and 8.5) have been implemented in the urban climate model UrbClim. The projections show that the influence of GHG emissions trumps urban planning measures in each period. In the near future, no large differences are seen between the RCP scenarios; in the far future, both heat stress and risk values are twice as large for RCP 8.5 compared to RCP 4.5. Depending on the GHG scenario and the LCZ type, heat stress is projected to increase by a factor of 10 by 2090 compared to the present-day climate and urban planning conditions. The imprint of vulnerability and exposure is clearly visible in the heat risk assessment, leading to very high levels of heat risk, most notably for the North Western part of the Brussels Capital Region. The results demonstrate the need for mitigation and adaptation plans at different policy levels that strive for lower GHG emissions and the development of sustainable urban areas safeguarding livability in cities

    Real-space renormalisation group approach to driven diffusive systems

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    We introduce a real-space renormalisation group procedure for driven diffusive systems which predicts both steady state and dynamic properties. We apply the method to the boundary driven asymmetric simple exclusion process and recover exact results for the steady state phase diagram, as well as the crossovers in the relaxation dynamics for each phase.Comment: 10 pages, 5 figure
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